| Full name: POU class 4 homeobox 3 | Alias Symbol: BRN3C | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 5459 | HGNC ID: HGNC:9220 | Ensembl Gene: ENSG00000091010 | OMIM ID: 602460 |
| Drug and gene relationship at DGIdb | |||
Expression of POU4F3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POU4F3 | 5459 | 208554_at | -0.0988 | 0.7555 | |
| GSE20347 | POU4F3 | 5459 | 208554_at | -0.0389 | 0.5828 | |
| GSE23400 | POU4F3 | 5459 | 208554_at | -0.1585 | 0.0000 | |
| GSE26886 | POU4F3 | 5459 | 208554_at | 0.1619 | 0.0874 | |
| GSE29001 | POU4F3 | 5459 | 208554_at | -0.0356 | 0.7514 | |
| GSE38129 | POU4F3 | 5459 | 208554_at | -0.0415 | 0.4503 | |
| GSE45670 | POU4F3 | 5459 | 208554_at | -0.0299 | 0.7183 | |
| GSE53622 | POU4F3 | 5459 | 73886 | 0.5967 | 0.0000 | |
| GSE53624 | POU4F3 | 5459 | 73886 | 0.7331 | 0.0000 | |
| GSE63941 | POU4F3 | 5459 | 208554_at | -0.0647 | 0.6222 | |
| GSE77861 | POU4F3 | 5459 | 208554_at | -0.0533 | 0.7203 | |
| GSE97050 | POU4F3 | 5459 | A_23_P121976 | -0.0169 | 0.9519 | |
| TCGA | POU4F3 | 5459 | RNAseq | 1.2185 | 0.0953 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POU4F3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POU4F3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POU4F3 | 5459 | 1 | 12 | 17 | |
| GSE20123 | POU4F3 | 5459 | 1 | 12 | 17 | |
| GSE43470 | POU4F3 | 5459 | 2 | 9 | 32 | |
| GSE46452 | POU4F3 | 5459 | 0 | 27 | 32 | |
| GSE47630 | POU4F3 | 5459 | 0 | 20 | 20 | |
| GSE54993 | POU4F3 | 5459 | 9 | 1 | 60 | |
| GSE54994 | POU4F3 | 5459 | 2 | 14 | 37 | |
| GSE60625 | POU4F3 | 5459 | 0 | 0 | 11 | |
| GSE74703 | POU4F3 | 5459 | 2 | 7 | 27 | |
| GSE74704 | POU4F3 | 5459 | 1 | 7 | 12 | |
| TCGA | POU4F3 | 5459 | 3 | 40 | 53 |
Total number of gains: 21; Total number of losses: 149; Total Number of normals: 318.
Somatic mutations of POU4F3:
Generating mutation plots.
Highly correlated genes for POU4F3:
Showing top 20/385 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POU4F3 | LELP1 | 0.787492 | 3 | 0 | 3 |
| POU4F3 | PRG3 | 0.758746 | 3 | 0 | 3 |
| POU4F3 | HCRT | 0.754094 | 4 | 0 | 4 |
| POU4F3 | GPD1 | 0.745934 | 3 | 0 | 3 |
| POU4F3 | TMEM37 | 0.739294 | 3 | 0 | 3 |
| POU4F3 | IQCD | 0.738082 | 3 | 0 | 3 |
| POU4F3 | ACR | 0.727923 | 3 | 0 | 3 |
| POU4F3 | SLC39A5 | 0.724495 | 3 | 0 | 3 |
| POU4F3 | DCD | 0.715436 | 3 | 0 | 3 |
| POU4F3 | AOC2 | 0.715415 | 3 | 0 | 3 |
| POU4F3 | IGSF21 | 0.708994 | 3 | 0 | 3 |
| POU4F3 | B3GALT1 | 0.704933 | 3 | 0 | 3 |
| POU4F3 | KIF17 | 0.694696 | 3 | 0 | 3 |
| POU4F3 | VCX2 | 0.693715 | 5 | 0 | 4 |
| POU4F3 | KLHL35 | 0.693052 | 4 | 0 | 4 |
| POU4F3 | FOLH1 | 0.681399 | 4 | 0 | 3 |
| POU4F3 | SRD5A2 | 0.680911 | 4 | 0 | 4 |
| POU4F3 | AQP6 | 0.679041 | 4 | 0 | 4 |
| POU4F3 | PGLYRP2 | 0.678572 | 3 | 0 | 3 |
| POU4F3 | ADAM20 | 0.677044 | 3 | 0 | 3 |
For details and further investigation, click here
