TMEM38B

 

Full name: transmembrane protein 38B Alias Symbol: FLJ10493|bA219P18.1|D4Ertd89e|TRIC-B
Type: protein-coding gene Cytoband: 9q31.2
Entrez ID: 55151 HGNC ID: HGNC:25535 Ensembl Gene: ENSG00000095209 OMIM ID: 611236
Drug and gene relationship at DGIdb

 

Expression of TMEM38B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM38B 55151 222735_at 0.4199 0.3021
GSE20347 TMEM38B 55151 218772_x_at 1.1645 0.0000
GSE23400 TMEM38B 55151 218772_x_at 0.8425 0.0000
GSE26886 TMEM38B 55151 222735_at 0.9663 0.0066
GSE29001 TMEM38B 55151 218772_x_at 1.0891 0.0099
GSE38129 TMEM38B 55151 218772_x_at 1.1148 0.0000
GSE45670 TMEM38B 55151 222735_at 0.3901 0.2526
GSE53622 TMEM38B 55151 45686 0.8972 0.0000
GSE53624 TMEM38B 55151 45686 1.1723 0.0000
GSE63941 TMEM38B 55151 222735_at -0.3622 0.6125
GSE77861 TMEM38B 55151 222736_s_at 0.4615 0.0200
GSE97050 TMEM38B 55151 A_33_P3401428 0.3583 0.3405
SRP007169 TMEM38B 55151 RNAseq 1.7614 0.0015
SRP008496 TMEM38B 55151 RNAseq 1.5768 0.0000
SRP064894 TMEM38B 55151 RNAseq 0.8402 0.0000
SRP133303 TMEM38B 55151 RNAseq 1.1694 0.0000
SRP159526 TMEM38B 55151 RNAseq 1.3212 0.0000
SRP193095 TMEM38B 55151 RNAseq 0.7000 0.0001
SRP219564 TMEM38B 55151 RNAseq 0.6504 0.0584
TCGA TMEM38B 55151 RNAseq 0.1575 0.0980

Upregulated datasets: 8; Downregulated datasets: 0.  

 

Survival by TMEM38B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM38B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM38B 55151 4 10 16
GSE20123 TMEM38B 55151 5 9 16
GSE43470 TMEM38B 55151 7 3 33
GSE46452 TMEM38B 55151 6 13 40
GSE47630 TMEM38B 55151 1 17 22
GSE54993 TMEM38B 55151 3 3 64
GSE54994 TMEM38B 55151 9 10 34
GSE60625 TMEM38B 55151 0 0 11
GSE74703 TMEM38B 55151 6 3 27
GSE74704 TMEM38B 55151 2 6 12
TCGA TMEM38B 55151 26 21 49

Total number of gains: 69; Total number of losses: 95; Total Number of normals: 324.  

 

Somatic mutations of TMEM38B:

 

Generating mutation plots.

 

Highly correlated genes for TMEM38B:

 

Showing top 20/1797 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM38BKCNE30.804311303
TMEM38BCCDC1270.779688303
TMEM38BDUS3L0.751837303
TMEM38BZNF6640.751258303
TMEM38BDHRSX0.746513404
TMEM38BEID10.741345303
TMEM38BSPPL2A0.731399303
TMEM38BMMS22L0.728891303
TMEM38BKPNA50.727898303
TMEM38BKTI120.726891303
TMEM38BDPYSL20.725677303
TMEM38BCSNK2A20.721464403
TMEM38BCCDC102B0.721127303
TMEM38BFNTA0.720915303
TMEM38BRFC20.718704808
TMEM38BMAGOH0.718687303
TMEM38BFCGR3A0.717291303
TMEM38BCHIC10.709916403
TMEM38BRRN30.709648505
TMEM38BZNF6690.708194303

For details and further investigation, click here