RFC2

 

Full name: replication factor C subunit 2 Alias Symbol: A1|RFC40
Type: protein-coding gene Cytoband: 7q11.23
Entrez ID: 5982 HGNC ID: HGNC:9970 Ensembl Gene: ENSG00000049541 OMIM ID: 600404
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RFC2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RFC2 5982 203696_s_at 0.6266 0.1406
GSE20347 RFC2 5982 203696_s_at 0.7664 0.0005
GSE23400 RFC2 5982 1053_at 0.3327 0.0000
GSE26886 RFC2 5982 203696_s_at 0.4464 0.0042
GSE29001 RFC2 5982 203696_s_at 0.2357 0.3368
GSE38129 RFC2 5982 203696_s_at 0.9284 0.0000
GSE45670 RFC2 5982 203696_s_at 0.4003 0.0199
GSE53622 RFC2 5982 117468 0.7954 0.0000
GSE53624 RFC2 5982 117468 0.8404 0.0000
GSE63941 RFC2 5982 203696_s_at 2.0116 0.0000
GSE77861 RFC2 5982 203696_s_at 0.3706 0.0345
GSE97050 RFC2 5982 A_23_P93823 0.4880 0.2295
SRP007169 RFC2 5982 RNAseq 1.0417 0.0384
SRP008496 RFC2 5982 RNAseq 0.9282 0.0082
SRP064894 RFC2 5982 RNAseq 0.8795 0.0006
SRP133303 RFC2 5982 RNAseq 0.8832 0.0000
SRP159526 RFC2 5982 RNAseq 0.9785 0.0001
SRP193095 RFC2 5982 RNAseq 0.7598 0.0000
SRP219564 RFC2 5982 RNAseq 0.7981 0.0073
TCGA RFC2 5982 RNAseq 0.3424 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by RFC2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RFC2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RFC2 5982 14 1 15
GSE20123 RFC2 5982 14 1 15
GSE43470 RFC2 5982 3 2 38
GSE46452 RFC2 5982 12 0 47
GSE47630 RFC2 5982 7 2 31
GSE54993 RFC2 5982 2 7 61
GSE54994 RFC2 5982 13 3 37
GSE60625 RFC2 5982 0 0 11
GSE74703 RFC2 5982 3 1 32
GSE74704 RFC2 5982 8 1 11
TCGA RFC2 5982 45 7 44

Total number of gains: 121; Total number of losses: 25; Total Number of normals: 342.  

 

Somatic mutations of RFC2:

 

Generating mutation plots.

 

Highly correlated genes for RFC2:

 

Showing top 20/1677 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RFC2CKAP2L0.776398707
RFC2MMS22L0.768167303
RFC2PBK0.76401811011
RFC2MAD2L10.76215610010
RFC2STARD70.760382909
RFC2ATAD20.75850211011
RFC2GMNN0.75767812012
RFC2CENPA0.75269111010
RFC2MCM60.7519412012
RFC2BORA0.751321909
RFC2RPA30.75058312012
RFC2NOL110.75047211011
RFC2NCAPG20.75017111011
RFC2EXO10.749111011
RFC2ANAPC10.748351303
RFC2WDHD10.74834412011
RFC2CDT10.74717712012
RFC2DBF40.74587612011
RFC2LSM50.74511812012
RFC2DKC10.744948303

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