| Full name: coiled-coil domain containing 127 | Alias Symbol: FLJ25701 | ||
| Type: protein-coding gene | Cytoband: 5p15.33 | ||
| Entrez ID: 133957 | HGNC ID: HGNC:30520 | Ensembl Gene: ENSG00000164366 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC127:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC127 | 133957 | 226515_at | 0.3841 | 0.2312 | |
| GSE26886 | CCDC127 | 133957 | 226515_at | -0.1207 | 0.7191 | |
| GSE45670 | CCDC127 | 133957 | 226515_at | -0.0986 | 0.6715 | |
| GSE53622 | CCDC127 | 133957 | 82823 | -0.0491 | 0.6590 | |
| GSE53624 | CCDC127 | 133957 | 82823 | 0.0839 | 0.2892 | |
| GSE63941 | CCDC127 | 133957 | 226515_at | 0.4643 | 0.3034 | |
| GSE77861 | CCDC127 | 133957 | 226515_at | 0.4358 | 0.0627 | |
| GSE97050 | CCDC127 | 133957 | A_23_P41976 | -0.4429 | 0.1163 | |
| SRP007169 | CCDC127 | 133957 | RNAseq | -1.0480 | 0.0377 | |
| SRP008496 | CCDC127 | 133957 | RNAseq | -1.0529 | 0.0020 | |
| SRP064894 | CCDC127 | 133957 | RNAseq | -0.3115 | 0.1730 | |
| SRP133303 | CCDC127 | 133957 | RNAseq | 0.0640 | 0.6612 | |
| SRP159526 | CCDC127 | 133957 | RNAseq | 0.5006 | 0.1129 | |
| SRP193095 | CCDC127 | 133957 | RNAseq | 0.0322 | 0.8233 | |
| SRP219564 | CCDC127 | 133957 | RNAseq | 0.1458 | 0.7776 | |
| TCGA | CCDC127 | 133957 | RNAseq | 0.1357 | 0.1021 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CCDC127 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC127:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC127 | 133957 | 12 | 2 | 16 | |
| GSE20123 | CCDC127 | 133957 | 12 | 1 | 17 | |
| GSE43470 | CCDC127 | 133957 | 16 | 0 | 27 | |
| GSE46452 | CCDC127 | 133957 | 6 | 22 | 31 | |
| GSE47630 | CCDC127 | 133957 | 11 | 9 | 20 | |
| GSE54993 | CCDC127 | 133957 | 5 | 6 | 59 | |
| GSE54994 | CCDC127 | 133957 | 29 | 1 | 23 | |
| GSE60625 | CCDC127 | 133957 | 0 | 0 | 11 | |
| GSE74703 | CCDC127 | 133957 | 13 | 0 | 23 | |
| GSE74704 | CCDC127 | 133957 | 11 | 0 | 9 | |
| TCGA | CCDC127 | 133957 | 60 | 4 | 32 |
Total number of gains: 175; Total number of losses: 45; Total Number of normals: 268.
Somatic mutations of CCDC127:
Generating mutation plots.
Highly correlated genes for CCDC127:
Showing top 20/279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC127 | ENY2 | 0.86328 | 3 | 0 | 3 |
| CCDC127 | TATDN1 | 0.854246 | 3 | 0 | 3 |
| CCDC127 | CCS | 0.84832 | 3 | 0 | 3 |
| CCDC127 | POLR2K | 0.834653 | 3 | 0 | 3 |
| CCDC127 | CHD1L | 0.829137 | 3 | 0 | 3 |
| CCDC127 | TCEA1 | 0.824503 | 3 | 0 | 3 |
| CCDC127 | NAPEPLD | 0.823333 | 3 | 0 | 3 |
| CCDC127 | P4HA1 | 0.807062 | 3 | 0 | 3 |
| CCDC127 | QSOX2 | 0.805334 | 3 | 0 | 3 |
| CCDC127 | ALS2 | 0.803585 | 3 | 0 | 3 |
| CCDC127 | DHRSX | 0.80356 | 3 | 0 | 3 |
| CCDC127 | WDR5 | 0.802324 | 3 | 0 | 3 |
| CCDC127 | SLC41A1 | 0.801622 | 3 | 0 | 3 |
| CCDC127 | NINJ1 | 0.801427 | 3 | 0 | 3 |
| CCDC127 | STK3 | 0.801328 | 3 | 0 | 3 |
| CCDC127 | TP53I13 | 0.799781 | 3 | 0 | 3 |
| CCDC127 | SLC25A37 | 0.798351 | 3 | 0 | 3 |
| CCDC127 | ATP6V1C1 | 0.798093 | 3 | 0 | 3 |
| CCDC127 | ORC2 | 0.797952 | 3 | 0 | 3 |
| CCDC127 | LPCAT1 | 0.7978 | 3 | 0 | 3 |
For details and further investigation, click here
