| Full name: cadherin 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 1002 | HGNC ID: HGNC:1763 | Ensembl Gene: ENSG00000179242 | OMIM ID: 603006 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH4 | 1002 | 206866_at | 0.1146 | 0.7262 | |
| GSE20347 | CDH4 | 1002 | 220227_at | 0.1878 | 0.1608 | |
| GSE23400 | CDH4 | 1002 | 220227_at | -0.0907 | 0.0348 | |
| GSE26886 | CDH4 | 1002 | 239485_at | 0.2866 | 0.0344 | |
| GSE29001 | CDH4 | 1002 | 220227_at | -0.0903 | 0.6236 | |
| GSE38129 | CDH4 | 1002 | 206866_at | 0.2635 | 0.1398 | |
| GSE45670 | CDH4 | 1002 | 239485_at | -0.0059 | 0.9614 | |
| GSE53622 | CDH4 | 1002 | 19148 | 0.0079 | 0.9409 | |
| GSE53624 | CDH4 | 1002 | 19148 | -0.0570 | 0.5943 | |
| GSE63941 | CDH4 | 1002 | 220227_at | -0.3497 | 0.6138 | |
| GSE77861 | CDH4 | 1002 | 239485_at | -0.0345 | 0.8778 | |
| GSE97050 | CDH4 | 1002 | A_23_P17593 | 0.2465 | 0.4137 | |
| SRP133303 | CDH4 | 1002 | RNAseq | 0.2580 | 0.3434 | |
| SRP159526 | CDH4 | 1002 | RNAseq | 0.6509 | 0.3460 | |
| SRP219564 | CDH4 | 1002 | RNAseq | -0.6633 | 0.2679 | |
| TCGA | CDH4 | 1002 | RNAseq | 0.0839 | 0.8829 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDH4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH4 | 1002 | 13 | 2 | 15 | |
| GSE20123 | CDH4 | 1002 | 14 | 2 | 14 | |
| GSE43470 | CDH4 | 1002 | 11 | 1 | 31 | |
| GSE46452 | CDH4 | 1002 | 35 | 0 | 24 | |
| GSE47630 | CDH4 | 1002 | 25 | 1 | 14 | |
| GSE54993 | CDH4 | 1002 | 0 | 17 | 53 | |
| GSE54994 | CDH4 | 1002 | 29 | 0 | 24 | |
| GSE60625 | CDH4 | 1002 | 0 | 0 | 11 | |
| GSE74703 | CDH4 | 1002 | 10 | 0 | 26 | |
| GSE74704 | CDH4 | 1002 | 11 | 0 | 9 | |
| TCGA | CDH4 | 1002 | 43 | 4 | 49 |
Total number of gains: 191; Total number of losses: 27; Total Number of normals: 270.
Somatic mutations of CDH4:
Generating mutation plots.
Highly correlated genes for CDH4:
Showing top 20/687 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH4 | MYO15B | 0.825929 | 3 | 0 | 3 |
| CDH4 | TBX4 | 0.805141 | 3 | 0 | 3 |
| CDH4 | DCAF15 | 0.799554 | 3 | 0 | 3 |
| CDH4 | HOTAIR | 0.775552 | 3 | 0 | 3 |
| CDH4 | SH2D5 | 0.774662 | 3 | 0 | 3 |
| CDH4 | JSRP1 | 0.764359 | 4 | 0 | 3 |
| CDH4 | NXNL1 | 0.761955 | 3 | 0 | 3 |
| CDH4 | ARHGAP30 | 0.755445 | 3 | 0 | 3 |
| CDH4 | FBLN7 | 0.754968 | 4 | 0 | 4 |
| CDH4 | CFC1 | 0.750088 | 4 | 0 | 4 |
| CDH4 | OBSL1 | 0.745948 | 4 | 0 | 4 |
| CDH4 | RPP25 | 0.74544 | 3 | 0 | 3 |
| CDH4 | LRFN1 | 0.740507 | 3 | 0 | 3 |
| CDH4 | SPRN | 0.739326 | 3 | 0 | 3 |
| CDH4 | TNXB | 0.73876 | 3 | 0 | 3 |
| CDH4 | FLCN | 0.736857 | 3 | 0 | 3 |
| CDH4 | LENG1 | 0.736571 | 3 | 0 | 3 |
| CDH4 | PRAMEF12 | 0.735055 | 3 | 0 | 3 |
| CDH4 | SLC6A3 | 0.733946 | 4 | 0 | 4 |
| CDH4 | PROC | 0.733363 | 3 | 0 | 3 |
For details and further investigation, click here
