| Full name: G protein nucleolar 1 (putative) | Alias Symbol: HSR1 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 2794 | HGNC ID: HGNC:4413 | Ensembl Gene: ENSG00000204590 | OMIM ID: 143024 |
| Drug and gene relationship at DGIdb | |||
Expression of GNL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GNL1 | 2794 | 203307_at | 0.4629 | 0.0561 | |
| GSE20347 | GNL1 | 2794 | 203307_at | 0.1394 | 0.1004 | |
| GSE23400 | GNL1 | 2794 | 203307_at | 0.0155 | 0.7614 | |
| GSE26886 | GNL1 | 2794 | 203307_at | 0.7181 | 0.0000 | |
| GSE29001 | GNL1 | 2794 | 203307_at | 0.2496 | 0.2121 | |
| GSE38129 | GNL1 | 2794 | 203307_at | 0.1802 | 0.0114 | |
| GSE45670 | GNL1 | 2794 | 203307_at | 0.2009 | 0.0159 | |
| GSE53622 | GNL1 | 2794 | 60408 | 0.2747 | 0.0000 | |
| GSE53624 | GNL1 | 2794 | 60408 | 0.4327 | 0.0000 | |
| GSE63941 | GNL1 | 2794 | 203307_at | -0.1136 | 0.7595 | |
| GSE77861 | GNL1 | 2794 | 203307_at | -0.0650 | 0.6538 | |
| GSE97050 | GNL1 | 2794 | A_23_P145289 | 0.1180 | 0.6337 | |
| SRP007169 | GNL1 | 2794 | RNAseq | 0.3065 | 0.3970 | |
| SRP008496 | GNL1 | 2794 | RNAseq | 0.3854 | 0.1347 | |
| SRP064894 | GNL1 | 2794 | RNAseq | 0.5606 | 0.0108 | |
| SRP133303 | GNL1 | 2794 | RNAseq | -0.0955 | 0.5302 | |
| SRP159526 | GNL1 | 2794 | RNAseq | 0.4583 | 0.0117 | |
| SRP193095 | GNL1 | 2794 | RNAseq | 0.3355 | 0.0001 | |
| SRP219564 | GNL1 | 2794 | RNAseq | 0.2052 | 0.2867 | |
| TCGA | GNL1 | 2794 | RNAseq | 0.0229 | 0.6457 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GNL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GNL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GNL1 | 2794 | 5 | 1 | 24 | |
| GSE20123 | GNL1 | 2794 | 5 | 1 | 24 | |
| GSE43470 | GNL1 | 2794 | 5 | 1 | 37 | |
| GSE46452 | GNL1 | 2794 | 1 | 10 | 48 | |
| GSE47630 | GNL1 | 2794 | 7 | 3 | 30 | |
| GSE54993 | GNL1 | 2794 | 2 | 1 | 67 | |
| GSE54994 | GNL1 | 2794 | 11 | 4 | 38 | |
| GSE60625 | GNL1 | 2794 | 0 | 1 | 10 | |
| GSE74703 | GNL1 | 2794 | 5 | 0 | 31 | |
| GSE74704 | GNL1 | 2794 | 2 | 0 | 18 | |
| TCGA | GNL1 | 2794 | 18 | 16 | 62 |
Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.
Somatic mutations of GNL1:
Generating mutation plots.
Highly correlated genes for GNL1:
Showing top 20/505 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GNL1 | JSRP1 | 0.808186 | 3 | 0 | 3 |
| GNL1 | TMEM102 | 0.800965 | 3 | 0 | 3 |
| GNL1 | C19orf44 | 0.800072 | 3 | 0 | 3 |
| GNL1 | C19orf81 | 0.790824 | 3 | 0 | 3 |
| GNL1 | MGAT5B | 0.786773 | 3 | 0 | 3 |
| GNL1 | LENG1 | 0.741918 | 3 | 0 | 3 |
| GNL1 | PNMA6A | 0.739236 | 3 | 0 | 3 |
| GNL1 | DUSP15 | 0.733516 | 3 | 0 | 3 |
| GNL1 | REG3A | 0.72963 | 3 | 0 | 3 |
| GNL1 | DNLZ | 0.721163 | 3 | 0 | 3 |
| GNL1 | GPR150 | 0.720064 | 3 | 0 | 3 |
| GNL1 | IQSEC3 | 0.719783 | 4 | 0 | 3 |
| GNL1 | EBF4 | 0.719773 | 4 | 0 | 3 |
| GNL1 | MATK | 0.716055 | 3 | 0 | 3 |
| GNL1 | FBRSL1 | 0.711641 | 4 | 0 | 3 |
| GNL1 | PYDC1 | 0.711484 | 3 | 0 | 3 |
| GNL1 | FOXA3 | 0.704258 | 3 | 0 | 3 |
| GNL1 | ZNF524 | 0.703325 | 4 | 0 | 3 |
| GNL1 | TNFRSF14 | 0.702863 | 3 | 0 | 3 |
| GNL1 | HDAC8 | 0.700463 | 4 | 0 | 3 |
For details and further investigation, click here
