| Full name: transition protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 7141 | HGNC ID: HGNC:11951 | Ensembl Gene: ENSG00000118245 | OMIM ID: 190231 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TNP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNP1 | 7141 | 206568_at | -0.0579 | 0.7954 | |
| GSE20347 | TNP1 | 7141 | 206568_at | -0.0877 | 0.1399 | |
| GSE23400 | TNP1 | 7141 | 206568_at | -0.0793 | 0.0030 | |
| GSE26886 | TNP1 | 7141 | 206568_at | -0.1258 | 0.2035 | |
| GSE29001 | TNP1 | 7141 | 206568_at | -0.1368 | 0.1957 | |
| GSE38129 | TNP1 | 7141 | 206568_at | -0.1108 | 0.1187 | |
| GSE45670 | TNP1 | 7141 | 206568_at | 0.0124 | 0.9148 | |
| GSE53622 | TNP1 | 7141 | 110160 | -0.2521 | 0.0058 | |
| GSE53624 | TNP1 | 7141 | 110160 | -0.3953 | 0.0000 | |
| GSE63941 | TNP1 | 7141 | 206568_at | 0.2799 | 0.0752 | |
| GSE77861 | TNP1 | 7141 | 206568_at | -0.1051 | 0.2943 | |
| GSE97050 | TNP1 | 7141 | A_23_P165504 | 0.0840 | 0.7253 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNP1 | 7141 | 1 | 13 | 16 | |
| GSE20123 | TNP1 | 7141 | 1 | 13 | 16 | |
| GSE43470 | TNP1 | 7141 | 0 | 7 | 36 | |
| GSE46452 | TNP1 | 7141 | 0 | 5 | 54 | |
| GSE47630 | TNP1 | 7141 | 4 | 5 | 31 | |
| GSE54993 | TNP1 | 7141 | 0 | 3 | 67 | |
| GSE54994 | TNP1 | 7141 | 8 | 9 | 36 | |
| GSE60625 | TNP1 | 7141 | 0 | 3 | 8 | |
| GSE74703 | TNP1 | 7141 | 0 | 6 | 30 | |
| GSE74704 | TNP1 | 7141 | 1 | 7 | 12 | |
| TCGA | TNP1 | 7141 | 11 | 27 | 58 |
Total number of gains: 26; Total number of losses: 98; Total Number of normals: 364.
Somatic mutations of TNP1:
Generating mutation plots.
Highly correlated genes for TNP1:
Showing top 20/608 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNP1 | CLEC18C | 0.776599 | 3 | 0 | 3 |
| TNP1 | CATSPER3 | 0.755647 | 3 | 0 | 3 |
| TNP1 | BARHL2 | 0.750261 | 3 | 0 | 3 |
| TNP1 | OR4D2 | 0.749912 | 4 | 0 | 3 |
| TNP1 | PPP1R3F | 0.748275 | 3 | 0 | 3 |
| TNP1 | BTBD9 | 0.730761 | 3 | 0 | 3 |
| TNP1 | RAB3IL1 | 0.724603 | 4 | 0 | 3 |
| TNP1 | CD300LG | 0.717438 | 4 | 0 | 3 |
| TNP1 | LCE1A | 0.716499 | 3 | 0 | 3 |
| TNP1 | OR13G1 | 0.71151 | 3 | 0 | 3 |
| TNP1 | CD164L2 | 0.711182 | 3 | 0 | 3 |
| TNP1 | BSND | 0.708796 | 4 | 0 | 4 |
| TNP1 | TLR8 | 0.706827 | 3 | 0 | 3 |
| TNP1 | B3GNT8 | 0.704715 | 3 | 0 | 3 |
| TNP1 | TPRX1 | 0.704185 | 3 | 0 | 3 |
| TNP1 | NHLRC4 | 0.701863 | 5 | 0 | 4 |
| TNP1 | ADAM20 | 0.700179 | 3 | 0 | 3 |
| TNP1 | THPO | 0.698415 | 5 | 0 | 4 |
| TNP1 | CRB2 | 0.697166 | 4 | 0 | 3 |
| TNP1 | NCAN | 0.696829 | 4 | 0 | 4 |
For details and further investigation, click here
