| Full name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 | Alias Symbol: BGALT15|beta3Gn-T8 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 374907 | HGNC ID: HGNC:24139 | Ensembl Gene: ENSG00000177191 | OMIM ID: 615357 |
| Drug and gene relationship at DGIdb | |||
Expression of B3GNT8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B3GNT8 | 374907 | 237338_at | -0.8767 | 0.1310 | |
| GSE26886 | B3GNT8 | 374907 | 237338_at | -0.7815 | 0.0004 | |
| GSE45670 | B3GNT8 | 374907 | 237338_at | -0.5668 | 0.0383 | |
| GSE63941 | B3GNT8 | 374907 | 237338_at | -0.0768 | 0.7460 | |
| GSE77861 | B3GNT8 | 374907 | 237338_at | -0.7876 | 0.0121 | |
| GSE97050 | B3GNT8 | 374907 | A_23_P101380 | -0.1865 | 0.4474 | |
| SRP007169 | B3GNT8 | 374907 | RNAseq | -4.7878 | 0.0000 | |
| SRP008496 | B3GNT8 | 374907 | RNAseq | -4.2450 | 0.0000 | |
| SRP064894 | B3GNT8 | 374907 | RNAseq | -2.5106 | 0.0000 | |
| SRP133303 | B3GNT8 | 374907 | RNAseq | -2.0629 | 0.0000 | |
| SRP159526 | B3GNT8 | 374907 | RNAseq | -2.6921 | 0.0000 | |
| SRP193095 | B3GNT8 | 374907 | RNAseq | -2.5474 | 0.0000 | |
| SRP219564 | B3GNT8 | 374907 | RNAseq | -2.7785 | 0.0003 | |
| TCGA | B3GNT8 | 374907 | RNAseq | 0.2225 | 0.2257 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by B3GNT8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of B3GNT8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B3GNT8 | 374907 | 4 | 4 | 22 | |
| GSE20123 | B3GNT8 | 374907 | 4 | 3 | 23 | |
| GSE43470 | B3GNT8 | 374907 | 3 | 11 | 29 | |
| GSE46452 | B3GNT8 | 374907 | 48 | 1 | 10 | |
| GSE47630 | B3GNT8 | 374907 | 9 | 5 | 26 | |
| GSE54993 | B3GNT8 | 374907 | 17 | 4 | 49 | |
| GSE54994 | B3GNT8 | 374907 | 7 | 11 | 35 | |
| GSE60625 | B3GNT8 | 374907 | 9 | 0 | 2 | |
| GSE74703 | B3GNT8 | 374907 | 3 | 7 | 26 | |
| GSE74704 | B3GNT8 | 374907 | 4 | 1 | 15 | |
| TCGA | B3GNT8 | 374907 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 63; Total Number of normals: 303.
Somatic mutations of B3GNT8:
Generating mutation plots.
Highly correlated genes for B3GNT8:
Showing top 20/576 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B3GNT8 | EPS8L2 | 0.848005 | 5 | 0 | 5 |
| B3GNT8 | MMEL1 | 0.805019 | 4 | 0 | 4 |
| B3GNT8 | C5orf66-AS1 | 0.792083 | 4 | 0 | 4 |
| B3GNT8 | ABLIM3 | 0.786901 | 5 | 0 | 5 |
| B3GNT8 | GYS2 | 0.784112 | 4 | 0 | 4 |
| B3GNT8 | PHACTR2 | 0.782605 | 3 | 0 | 3 |
| B3GNT8 | ATG9B | 0.781215 | 4 | 0 | 4 |
| B3GNT8 | FUT6 | 0.779687 | 4 | 0 | 4 |
| B3GNT8 | PADI1 | 0.779506 | 4 | 0 | 4 |
| B3GNT8 | MAPK3 | 0.777646 | 4 | 0 | 4 |
| B3GNT8 | SLC35C1 | 0.777645 | 5 | 0 | 5 |
| B3GNT8 | CD300LG | 0.775788 | 3 | 0 | 3 |
| B3GNT8 | PTK6 | 0.770719 | 6 | 0 | 5 |
| B3GNT8 | RALYL | 0.769412 | 3 | 0 | 3 |
| B3GNT8 | SFTA2 | 0.769026 | 4 | 0 | 4 |
| B3GNT8 | FBXO34 | 0.766567 | 5 | 0 | 5 |
| B3GNT8 | TNNI2 | 0.764057 | 3 | 0 | 3 |
| B3GNT8 | BCKDHA | 0.76254 | 5 | 0 | 5 |
| B3GNT8 | GAB2 | 0.760352 | 5 | 0 | 5 |
| B3GNT8 | SHOC2 | 0.76032 | 4 | 0 | 4 |
For details and further investigation, click here
