| Full name: crumbs cell polarity complex component 2 | Alias Symbol: FLJ38464|FLJ16786 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 286204 | HGNC ID: HGNC:18688 | Ensembl Gene: ENSG00000148204 | OMIM ID: 609720 |
| Drug and gene relationship at DGIdb | |||
Expression of CRB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRB2 | 286204 | 1552506_at | -0.1618 | 0.4605 | |
| GSE26886 | CRB2 | 286204 | 1552506_at | -0.1487 | 0.1685 | |
| GSE45670 | CRB2 | 286204 | 1552506_at | 0.0386 | 0.7498 | |
| GSE53622 | CRB2 | 286204 | 85627 | 0.4361 | 0.0000 | |
| GSE53624 | CRB2 | 286204 | 85627 | 0.4286 | 0.0000 | |
| GSE63941 | CRB2 | 286204 | 1552506_at | -0.0303 | 0.8215 | |
| GSE77861 | CRB2 | 286204 | 1552506_at | -0.0826 | 0.4057 | |
| GSE97050 | CRB2 | 286204 | A_24_P326398 | 0.0686 | 0.7849 | |
| SRP133303 | CRB2 | 286204 | RNAseq | -0.3872 | 0.4694 | |
| TCGA | CRB2 | 286204 | RNAseq | -0.4496 | 0.2796 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRB2 | 286204 | 3 | 8 | 19 | |
| GSE20123 | CRB2 | 286204 | 3 | 8 | 19 | |
| GSE43470 | CRB2 | 286204 | 5 | 4 | 34 | |
| GSE46452 | CRB2 | 286204 | 6 | 13 | 40 | |
| GSE47630 | CRB2 | 286204 | 3 | 16 | 21 | |
| GSE54993 | CRB2 | 286204 | 3 | 3 | 64 | |
| GSE54994 | CRB2 | 286204 | 9 | 10 | 34 | |
| GSE60625 | CRB2 | 286204 | 0 | 0 | 11 | |
| GSE74703 | CRB2 | 286204 | 5 | 3 | 28 | |
| GSE74704 | CRB2 | 286204 | 2 | 6 | 12 | |
| TCGA | CRB2 | 286204 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 95; Total Number of normals: 327.
Somatic mutations of CRB2:
Generating mutation plots.
Highly correlated genes for CRB2:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRB2 | ARHGDIG | 0.785308 | 3 | 0 | 3 |
| CRB2 | CTSE | 0.764771 | 3 | 0 | 3 |
| CRB2 | FHAD1 | 0.754689 | 3 | 0 | 3 |
| CRB2 | KIF17 | 0.751185 | 3 | 0 | 3 |
| CRB2 | HCRT | 0.750012 | 3 | 0 | 3 |
| CRB2 | ITIH3 | 0.748529 | 3 | 0 | 3 |
| CRB2 | SLC19A3 | 0.742822 | 3 | 0 | 3 |
| CRB2 | MUC2 | 0.741968 | 3 | 0 | 3 |
| CRB2 | KCNK9 | 0.731909 | 3 | 0 | 3 |
| CRB2 | IGHMBP2 | 0.73051 | 3 | 0 | 3 |
| CRB2 | CELF4 | 0.725971 | 3 | 0 | 3 |
| CRB2 | GP9 | 0.71941 | 4 | 0 | 3 |
| CRB2 | FAM71F1 | 0.718023 | 4 | 0 | 3 |
| CRB2 | CIB3 | 0.71548 | 4 | 0 | 4 |
| CRB2 | MUC8 | 0.714825 | 4 | 0 | 4 |
| CRB2 | SERTM1 | 0.711978 | 3 | 0 | 3 |
| CRB2 | GSTM5 | 0.709413 | 3 | 0 | 3 |
| CRB2 | C10orf91 | 0.70913 | 3 | 0 | 3 |
| CRB2 | MYO15B | 0.708215 | 3 | 0 | 3 |
| CRB2 | REG3A | 0.703927 | 3 | 0 | 3 |
For details and further investigation, click here
