| Full name: tRNA aspartic acid methyltransferase 1 | Alias Symbol: RNMT1 | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 1787 | HGNC ID: HGNC:2977 | Ensembl Gene: ENSG00000107614 | OMIM ID: 602478 |
| Drug and gene relationship at DGIdb | |||
Expression of TRDMT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRDMT1 | 1787 | 206308_at | -0.1359 | 0.7678 | |
| GSE20347 | TRDMT1 | 1787 | 206308_at | 0.0022 | 0.9897 | |
| GSE23400 | TRDMT1 | 1787 | 206308_at | 0.0553 | 0.0744 | |
| GSE26886 | TRDMT1 | 1787 | 206308_at | -0.2344 | 0.2976 | |
| GSE29001 | TRDMT1 | 1787 | 206308_at | 0.0879 | 0.7474 | |
| GSE38129 | TRDMT1 | 1787 | 206308_at | -0.0458 | 0.7484 | |
| GSE45670 | TRDMT1 | 1787 | 206308_at | -0.1398 | 0.4652 | |
| GSE53622 | TRDMT1 | 1787 | 906 | -0.0777 | 0.5285 | |
| GSE53624 | TRDMT1 | 1787 | 22801 | 0.1254 | 0.1068 | |
| GSE63941 | TRDMT1 | 1787 | 206308_at | -0.4628 | 0.2039 | |
| GSE77861 | TRDMT1 | 1787 | 232121_at | 0.0209 | 0.8565 | |
| GSE97050 | TRDMT1 | 1787 | A_23_P115636 | 0.1162 | 0.6594 | |
| SRP007169 | TRDMT1 | 1787 | RNAseq | 0.1438 | 0.8564 | |
| SRP008496 | TRDMT1 | 1787 | RNAseq | 0.8405 | 0.0941 | |
| SRP064894 | TRDMT1 | 1787 | RNAseq | -0.0975 | 0.5876 | |
| SRP133303 | TRDMT1 | 1787 | RNAseq | -0.2938 | 0.0663 | |
| SRP159526 | TRDMT1 | 1787 | RNAseq | 0.0781 | 0.8471 | |
| SRP193095 | TRDMT1 | 1787 | RNAseq | 0.0080 | 0.9429 | |
| SRP219564 | TRDMT1 | 1787 | RNAseq | -0.1787 | 0.6641 | |
| TCGA | TRDMT1 | 1787 | RNAseq | -0.0919 | 0.3486 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRDMT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRDMT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRDMT1 | 1787 | 3 | 8 | 19 | |
| GSE20123 | TRDMT1 | 1787 | 3 | 7 | 20 | |
| GSE43470 | TRDMT1 | 1787 | 3 | 4 | 36 | |
| GSE46452 | TRDMT1 | 1787 | 1 | 14 | 44 | |
| GSE47630 | TRDMT1 | 1787 | 5 | 15 | 20 | |
| GSE54993 | TRDMT1 | 1787 | 10 | 0 | 60 | |
| GSE54994 | TRDMT1 | 1787 | 4 | 9 | 40 | |
| GSE60625 | TRDMT1 | 1787 | 0 | 0 | 11 | |
| GSE74703 | TRDMT1 | 1787 | 2 | 3 | 31 | |
| GSE74704 | TRDMT1 | 1787 | 0 | 6 | 14 | |
| TCGA | TRDMT1 | 1787 | 19 | 26 | 51 |
Total number of gains: 50; Total number of losses: 92; Total Number of normals: 346.
Somatic mutations of TRDMT1:
Generating mutation plots.
Highly correlated genes for TRDMT1:
Showing top 20/25 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRDMT1 | ZC3H10 | 0.716855 | 3 | 0 | 3 |
| TRDMT1 | FAHD2A | 0.707364 | 3 | 0 | 3 |
| TRDMT1 | OPTC | 0.688853 | 3 | 0 | 3 |
| TRDMT1 | DCPS | 0.685172 | 3 | 0 | 3 |
| TRDMT1 | DACH1 | 0.68265 | 4 | 0 | 3 |
| TRDMT1 | ZNF235 | 0.656907 | 4 | 0 | 3 |
| TRDMT1 | TRIM2 | 0.652656 | 3 | 0 | 3 |
| TRDMT1 | ZNF326 | 0.639221 | 3 | 0 | 3 |
| TRDMT1 | ETV1 | 0.625325 | 4 | 0 | 3 |
| TRDMT1 | SYNJ2 | 0.619675 | 4 | 0 | 4 |
| TRDMT1 | RANGRF | 0.612777 | 3 | 0 | 3 |
| TRDMT1 | CUTC | 0.60873 | 4 | 0 | 3 |
| TRDMT1 | BST1 | 0.599943 | 4 | 0 | 3 |
| TRDMT1 | B3GNTL1 | 0.599839 | 3 | 0 | 3 |
| TRDMT1 | ZNF230 | 0.597215 | 5 | 0 | 4 |
| TRDMT1 | C19orf53 | 0.597187 | 4 | 0 | 3 |
| TRDMT1 | UROD | 0.597161 | 3 | 0 | 3 |
| TRDMT1 | TBX3 | 0.583284 | 6 | 0 | 4 |
| TRDMT1 | ZNF222 | 0.582653 | 4 | 0 | 3 |
| TRDMT1 | C12orf10 | 0.57472 | 4 | 0 | 3 |
For details and further investigation, click here
