| Full name: synaptojanin 2 | Alias Symbol: INPP5H | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 8871 | HGNC ID: HGNC:11504 | Ensembl Gene: ENSG00000078269 | OMIM ID: 609410 |
| Drug and gene relationship at DGIdb | |||
Expression of SYNJ2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYNJ2 | 8871 | 212828_at | -0.0790 | 0.8667 | |
| GSE20347 | SYNJ2 | 8871 | 216180_s_at | -0.0287 | 0.8222 | |
| GSE23400 | SYNJ2 | 8871 | 216181_at | -0.2259 | 0.0000 | |
| GSE26886 | SYNJ2 | 8871 | 212828_at | -0.4930 | 0.0235 | |
| GSE29001 | SYNJ2 | 8871 | 212828_at | -0.3096 | 0.1614 | |
| GSE38129 | SYNJ2 | 8871 | 212828_at | -0.1878 | 0.2426 | |
| GSE45670 | SYNJ2 | 8871 | 212828_at | -0.0849 | 0.6772 | |
| GSE53622 | SYNJ2 | 8871 | 76362 | -0.3127 | 0.0001 | |
| GSE53624 | SYNJ2 | 8871 | 76362 | -0.3123 | 0.0000 | |
| GSE63941 | SYNJ2 | 8871 | 212828_at | -1.1868 | 0.0647 | |
| GSE77861 | SYNJ2 | 8871 | 216180_s_at | -0.0249 | 0.9155 | |
| GSE97050 | SYNJ2 | 8871 | A_23_P316974 | -0.1424 | 0.5744 | |
| SRP007169 | SYNJ2 | 8871 | RNAseq | 0.4967 | 0.1517 | |
| SRP008496 | SYNJ2 | 8871 | RNAseq | 0.1893 | 0.4995 | |
| SRP064894 | SYNJ2 | 8871 | RNAseq | -0.2924 | 0.2025 | |
| SRP133303 | SYNJ2 | 8871 | RNAseq | 0.1678 | 0.3575 | |
| SRP159526 | SYNJ2 | 8871 | RNAseq | -0.2638 | 0.1825 | |
| SRP193095 | SYNJ2 | 8871 | RNAseq | 0.3441 | 0.0253 | |
| SRP219564 | SYNJ2 | 8871 | RNAseq | -0.2035 | 0.5871 | |
| TCGA | SYNJ2 | 8871 | RNAseq | -0.3280 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYNJ2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYNJ2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYNJ2 | 8871 | 2 | 5 | 23 | |
| GSE20123 | SYNJ2 | 8871 | 2 | 4 | 24 | |
| GSE43470 | SYNJ2 | 8871 | 4 | 0 | 39 | |
| GSE46452 | SYNJ2 | 8871 | 3 | 10 | 46 | |
| GSE47630 | SYNJ2 | 8871 | 9 | 4 | 27 | |
| GSE54993 | SYNJ2 | 8871 | 3 | 2 | 65 | |
| GSE54994 | SYNJ2 | 8871 | 8 | 9 | 36 | |
| GSE60625 | SYNJ2 | 8871 | 0 | 1 | 10 | |
| GSE74703 | SYNJ2 | 8871 | 4 | 0 | 32 | |
| GSE74704 | SYNJ2 | 8871 | 0 | 2 | 18 | |
| TCGA | SYNJ2 | 8871 | 14 | 22 | 60 |
Total number of gains: 49; Total number of losses: 59; Total Number of normals: 380.
Somatic mutations of SYNJ2:
Generating mutation plots.
Highly correlated genes for SYNJ2:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYNJ2 | ADM2 | 0.701657 | 3 | 0 | 3 |
| SYNJ2 | ZC3H10 | 0.652543 | 3 | 0 | 3 |
| SYNJ2 | CYP2F1 | 0.652489 | 3 | 0 | 3 |
| SYNJ2 | ACSL6 | 0.642381 | 3 | 0 | 3 |
| SYNJ2 | INPP4B | 0.638779 | 3 | 0 | 3 |
| SYNJ2 | S100A1 | 0.625423 | 3 | 0 | 3 |
| SYNJ2 | TRDMT1 | 0.619675 | 4 | 0 | 4 |
| SYNJ2 | PSPN | 0.617899 | 3 | 0 | 3 |
| SYNJ2 | TMEM63A | 0.6036 | 3 | 0 | 3 |
| SYNJ2 | ADAMTS17 | 0.597137 | 3 | 0 | 3 |
| SYNJ2 | GRIPAP1 | 0.596012 | 4 | 0 | 4 |
| SYNJ2 | PDZRN3 | 0.594003 | 4 | 0 | 4 |
| SYNJ2 | FUT7 | 0.593307 | 4 | 0 | 3 |
| SYNJ2 | MBP | 0.58928 | 4 | 0 | 3 |
| SYNJ2 | NPPC | 0.587199 | 4 | 0 | 3 |
| SYNJ2 | KRT36 | 0.577656 | 3 | 0 | 3 |
| SYNJ2 | NPPA | 0.576338 | 4 | 0 | 3 |
| SYNJ2 | SLC7A10 | 0.562779 | 3 | 0 | 3 |
| SYNJ2 | MASP2 | 0.561488 | 3 | 0 | 3 |
| SYNJ2 | TNNC2 | 0.560664 | 4 | 0 | 3 |
For details and further investigation, click here
