| Full name: bone marrow stromal cell antigen 1 | Alias Symbol: CD157 | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 683 | HGNC ID: HGNC:1118 | Ensembl Gene: ENSG00000109743 | OMIM ID: 600387 |
| Drug and gene relationship at DGIdb | |||
BST1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04970 | Salivary secretion | |
| hsa04972 | Pancreatic secretion |
Expression of BST1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BST1 | 683 | 205715_at | 0.7827 | 0.6403 | |
| GSE20347 | BST1 | 683 | 205715_at | 0.1316 | 0.3778 | |
| GSE23400 | BST1 | 683 | 205715_at | -0.0122 | 0.7839 | |
| GSE26886 | BST1 | 683 | 205715_at | 0.0678 | 0.8240 | |
| GSE29001 | BST1 | 683 | 205715_at | 0.1911 | 0.1734 | |
| GSE38129 | BST1 | 683 | 205715_at | -0.0380 | 0.8451 | |
| GSE45670 | BST1 | 683 | 205715_at | -0.8042 | 0.0029 | |
| GSE53622 | BST1 | 683 | 58953 | 0.0920 | 0.5307 | |
| GSE53624 | BST1 | 683 | 58953 | 0.2715 | 0.1105 | |
| GSE63941 | BST1 | 683 | 205715_at | -1.5796 | 0.2036 | |
| GSE77861 | BST1 | 683 | 205715_at | 0.0136 | 0.9533 | |
| GSE97050 | BST1 | 683 | A_23_P7325 | -0.0408 | 0.8657 | |
| SRP007169 | BST1 | 683 | RNAseq | 2.7092 | 0.0007 | |
| SRP064894 | BST1 | 683 | RNAseq | 0.2631 | 0.3989 | |
| SRP133303 | BST1 | 683 | RNAseq | 0.4051 | 0.2125 | |
| SRP159526 | BST1 | 683 | RNAseq | 1.9044 | 0.0290 | |
| SRP193095 | BST1 | 683 | RNAseq | 0.4593 | 0.1080 | |
| SRP219564 | BST1 | 683 | RNAseq | 0.5829 | 0.3318 | |
| TCGA | BST1 | 683 | RNAseq | -0.0039 | 0.9866 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by BST1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BST1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BST1 | 683 | 0 | 18 | 12 | |
| GSE20123 | BST1 | 683 | 0 | 18 | 12 | |
| GSE43470 | BST1 | 683 | 1 | 15 | 27 | |
| GSE46452 | BST1 | 683 | 1 | 36 | 22 | |
| GSE47630 | BST1 | 683 | 1 | 19 | 20 | |
| GSE54993 | BST1 | 683 | 10 | 0 | 60 | |
| GSE54994 | BST1 | 683 | 4 | 12 | 37 | |
| GSE60625 | BST1 | 683 | 0 | 0 | 11 | |
| GSE74703 | BST1 | 683 | 1 | 13 | 22 | |
| GSE74704 | BST1 | 683 | 0 | 11 | 9 | |
| TCGA | BST1 | 683 | 9 | 48 | 39 |
Total number of gains: 27; Total number of losses: 190; Total Number of normals: 271.
Somatic mutations of BST1:
Generating mutation plots.
Highly correlated genes for BST1:
Showing top 20/105 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BST1 | CHGB | 0.789242 | 3 | 0 | 3 |
| BST1 | ENPP2 | 0.67863 | 3 | 0 | 3 |
| BST1 | PPOX | 0.638421 | 4 | 0 | 3 |
| BST1 | FOXA1 | 0.617544 | 3 | 0 | 3 |
| BST1 | FAT4 | 0.615086 | 4 | 0 | 3 |
| BST1 | THAP3 | 0.614141 | 4 | 0 | 3 |
| BST1 | NTHL1 | 0.613424 | 3 | 0 | 3 |
| BST1 | ECM2 | 0.612714 | 6 | 0 | 6 |
| BST1 | TMEM120B | 0.608178 | 5 | 0 | 3 |
| BST1 | USP27X | 0.60809 | 4 | 0 | 4 |
| BST1 | LDB2 | 0.607914 | 4 | 0 | 3 |
| BST1 | ASMTL | 0.602605 | 4 | 0 | 3 |
| BST1 | SLC27A5 | 0.602549 | 5 | 0 | 4 |
| BST1 | KLHL26 | 0.602467 | 4 | 0 | 3 |
| BST1 | MEF2C | 0.600537 | 6 | 0 | 5 |
| BST1 | TRDMT1 | 0.599943 | 4 | 0 | 3 |
| BST1 | C15orf65 | 0.599749 | 3 | 0 | 3 |
| BST1 | TSPAN15 | 0.597357 | 4 | 0 | 3 |
| BST1 | BMPR1B | 0.597341 | 5 | 0 | 4 |
| BST1 | TNNC2 | 0.594027 | 4 | 0 | 4 |
For details and further investigation, click here
