| Full name: ETS variant transcription factor 1 | Alias Symbol: ER81 | ||
| Type: protein-coding gene | Cytoband: 7p21.2 | ||
| Entrez ID: 2115 | HGNC ID: HGNC:3490 | Ensembl Gene: ENSG00000006468 | OMIM ID: 600541 |
| Drug and gene relationship at DGIdb | |||
Expression of ETV1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETV1 | 2115 | 221911_at | -0.7160 | 0.5462 | |
| GSE20347 | ETV1 | 2115 | 221911_at | 0.6434 | 0.0504 | |
| GSE23400 | ETV1 | 2115 | 206501_x_at | -0.0627 | 0.1909 | |
| GSE26886 | ETV1 | 2115 | 206501_x_at | -0.0794 | 0.6436 | |
| GSE29001 | ETV1 | 2115 | 221911_at | -0.0240 | 0.9711 | |
| GSE38129 | ETV1 | 2115 | 221911_at | 0.4793 | 0.1514 | |
| GSE45670 | ETV1 | 2115 | 221911_at | -1.4421 | 0.0194 | |
| GSE53622 | ETV1 | 2115 | 2159 | 0.3321 | 0.0828 | |
| GSE53624 | ETV1 | 2115 | 2159 | 0.3626 | 0.0336 | |
| GSE63941 | ETV1 | 2115 | 206501_x_at | 0.3207 | 0.7604 | |
| GSE77861 | ETV1 | 2115 | 206501_x_at | -0.0264 | 0.8110 | |
| GSE97050 | ETV1 | 2115 | A_33_P3357954 | -0.1363 | 0.6568 | |
| SRP007169 | ETV1 | 2115 | RNAseq | 2.7115 | 0.0020 | |
| SRP008496 | ETV1 | 2115 | RNAseq | 2.6800 | 0.0003 | |
| SRP064894 | ETV1 | 2115 | RNAseq | -1.0459 | 0.0122 | |
| SRP133303 | ETV1 | 2115 | RNAseq | -0.5128 | 0.2750 | |
| SRP159526 | ETV1 | 2115 | RNAseq | 2.1374 | 0.0000 | |
| SRP193095 | ETV1 | 2115 | RNAseq | 0.7734 | 0.0015 | |
| SRP219564 | ETV1 | 2115 | RNAseq | 0.6278 | 0.4156 | |
| TCGA | ETV1 | 2115 | RNAseq | 0.1786 | 0.2892 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by ETV1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETV1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETV1 | 2115 | 14 | 2 | 14 | |
| GSE20123 | ETV1 | 2115 | 14 | 2 | 14 | |
| GSE43470 | ETV1 | 2115 | 5 | 0 | 38 | |
| GSE46452 | ETV1 | 2115 | 11 | 1 | 47 | |
| GSE47630 | ETV1 | 2115 | 9 | 1 | 30 | |
| GSE54993 | ETV1 | 2115 | 0 | 6 | 64 | |
| GSE54994 | ETV1 | 2115 | 21 | 1 | 31 | |
| GSE60625 | ETV1 | 2115 | 0 | 0 | 11 | |
| GSE74703 | ETV1 | 2115 | 5 | 0 | 31 | |
| GSE74704 | ETV1 | 2115 | 8 | 2 | 10 | |
| TCGA | ETV1 | 2115 | 55 | 6 | 35 |
Total number of gains: 142; Total number of losses: 21; Total Number of normals: 325.
Somatic mutations of ETV1:
Generating mutation plots.
Highly correlated genes for ETV1:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETV1 | PLCB4 | 0.705152 | 5 | 0 | 5 |
| ETV1 | ZNF575 | 0.691513 | 3 | 0 | 3 |
| ETV1 | LINC00261 | 0.675417 | 3 | 0 | 3 |
| ETV1 | ADAMTS19 | 0.660748 | 3 | 0 | 3 |
| ETV1 | SERTAD4-AS1 | 0.657315 | 4 | 0 | 4 |
| ETV1 | SLC25A4 | 0.651203 | 4 | 0 | 3 |
| ETV1 | LGALS13 | 0.640553 | 3 | 0 | 3 |
| ETV1 | NPR1 | 0.639729 | 4 | 0 | 3 |
| ETV1 | MPP2 | 0.633065 | 3 | 0 | 3 |
| ETV1 | PALLD | 0.631188 | 3 | 0 | 3 |
| ETV1 | DAPK1 | 0.627499 | 4 | 0 | 3 |
| ETV1 | TRDMT1 | 0.625325 | 4 | 0 | 3 |
| ETV1 | NPR2 | 0.624262 | 5 | 0 | 4 |
| ETV1 | GDNF | 0.623734 | 4 | 0 | 3 |
| ETV1 | AQP4 | 0.622471 | 3 | 0 | 3 |
| ETV1 | FBXL2 | 0.621664 | 4 | 0 | 3 |
| ETV1 | ADH6 | 0.613778 | 3 | 0 | 3 |
| ETV1 | SGCE | 0.608484 | 6 | 0 | 5 |
| ETV1 | PSIP1 | 0.607137 | 4 | 0 | 3 |
| ETV1 | AXIN2 | 0.606702 | 4 | 0 | 3 |
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