| Full name: fumarylacetoacetate hydrolase domain containing 2A | Alias Symbol: CGI-105 | ||
| Type: protein-coding gene | Cytoband: 2q11.1 | ||
| Entrez ID: 51011 | HGNC ID: HGNC:24252 | Ensembl Gene: ENSG00000115042 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAHD2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAHD2A | 51011 | 222056_s_at | 0.0695 | 0.8983 | |
| GSE20347 | FAHD2A | 51011 | 222056_s_at | 0.1268 | 0.5052 | |
| GSE23400 | FAHD2A | 51011 | 222056_s_at | 0.1005 | 0.1858 | |
| GSE26886 | FAHD2A | 51011 | 222056_s_at | 0.9740 | 0.0012 | |
| GSE29001 | FAHD2A | 51011 | 222056_s_at | 0.1383 | 0.6067 | |
| GSE38129 | FAHD2A | 51011 | 222056_s_at | -0.0187 | 0.9171 | |
| GSE45670 | FAHD2A | 51011 | 222056_s_at | -0.0550 | 0.7885 | |
| GSE53622 | FAHD2A | 51011 | 55799 | 0.3674 | 0.0000 | |
| GSE53624 | FAHD2A | 51011 | 55799 | 0.3655 | 0.0000 | |
| GSE63941 | FAHD2A | 51011 | 222056_s_at | 0.1100 | 0.8486 | |
| GSE77861 | FAHD2A | 51011 | 235418_at | -0.1309 | 0.3093 | |
| GSE97050 | FAHD2A | 51011 | A_23_P5731 | 0.2467 | 0.2925 | |
| SRP007169 | FAHD2A | 51011 | RNAseq | 1.1013 | 0.0675 | |
| SRP064894 | FAHD2A | 51011 | RNAseq | 0.3333 | 0.1460 | |
| SRP133303 | FAHD2A | 51011 | RNAseq | -0.1307 | 0.2027 | |
| SRP159526 | FAHD2A | 51011 | RNAseq | 1.2773 | 0.0127 | |
| SRP193095 | FAHD2A | 51011 | RNAseq | 0.1688 | 0.1557 | |
| SRP219564 | FAHD2A | 51011 | RNAseq | -0.0311 | 0.9267 | |
| TCGA | FAHD2A | 51011 | RNAseq | -0.1907 | 0.0095 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FAHD2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAHD2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAHD2A | 51011 | 6 | 2 | 22 | |
| GSE20123 | FAHD2A | 51011 | 6 | 2 | 22 | |
| GSE43470 | FAHD2A | 51011 | 3 | 2 | 38 | |
| GSE46452 | FAHD2A | 51011 | 2 | 3 | 54 | |
| GSE47630 | FAHD2A | 51011 | 7 | 0 | 33 | |
| GSE54993 | FAHD2A | 51011 | 0 | 6 | 64 | |
| GSE54994 | FAHD2A | 51011 | 11 | 0 | 42 | |
| GSE60625 | FAHD2A | 51011 | 0 | 3 | 8 | |
| GSE74703 | FAHD2A | 51011 | 3 | 1 | 32 | |
| GSE74704 | FAHD2A | 51011 | 4 | 1 | 15 | |
| TCGA | FAHD2A | 51011 | 35 | 4 | 57 |
Total number of gains: 77; Total number of losses: 24; Total Number of normals: 387.
Somatic mutations of FAHD2A:
Generating mutation plots.
Highly correlated genes for FAHD2A:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAHD2A | TRDMT1 | 0.707364 | 3 | 0 | 3 |
| FAHD2A | SLC13A3 | 0.707209 | 3 | 0 | 3 |
| FAHD2A | CCDC106 | 0.698762 | 3 | 0 | 3 |
| FAHD2A | BAALC | 0.696013 | 3 | 0 | 3 |
| FAHD2A | PTGER1 | 0.695814 | 3 | 0 | 3 |
| FAHD2A | WDR38 | 0.692751 | 3 | 0 | 3 |
| FAHD2A | DOHH | 0.691644 | 3 | 0 | 3 |
| FAHD2A | MYBPH | 0.683658 | 3 | 0 | 3 |
| FAHD2A | SCRN2 | 0.674192 | 4 | 0 | 3 |
| FAHD2A | GPR17 | 0.672172 | 3 | 0 | 3 |
| FAHD2A | GNL1 | 0.667687 | 3 | 0 | 3 |
| FAHD2A | HIRIP3 | 0.663761 | 4 | 0 | 4 |
| FAHD2A | FOXJ1 | 0.663756 | 3 | 0 | 3 |
| FAHD2A | OR2C3 | 0.657485 | 3 | 0 | 3 |
| FAHD2A | IL17B | 0.653059 | 3 | 0 | 3 |
| FAHD2A | SNHG19 | 0.6463 | 3 | 0 | 3 |
| FAHD2A | AGRP | 0.636918 | 3 | 0 | 3 |
| FAHD2A | TMEM198 | 0.631478 | 4 | 0 | 3 |
| FAHD2A | ITGA2B | 0.631237 | 4 | 0 | 3 |
| FAHD2A | CLCN6 | 0.624155 | 4 | 0 | 3 |
For details and further investigation, click here
