ZNF75A

 

Full name: zinc finger protein 75a Alias Symbol: FLJ31529
Type: protein-coding gene Cytoband: 16p13.3
Entrez ID: 7627 HGNC ID: HGNC:13146 Ensembl Gene: ENSG00000162086 OMIM ID: 601473
Drug and gene relationship at DGIdb

 

Expression of ZNF75A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF75A 7627 227670_at 0.2297 0.8114
GSE26886 ZNF75A 7627 242633_x_at 0.2317 0.2465
GSE45670 ZNF75A 7627 227670_at 0.3984 0.0317
GSE53622 ZNF75A 7627 98476 0.1600 0.0457
GSE53624 ZNF75A 7627 98476 0.2525 0.0003
GSE63941 ZNF75A 7627 242633_x_at -0.0424 0.8810
GSE77861 ZNF75A 7627 242633_x_at 0.1663 0.5111
GSE97050 ZNF75A 7627 A_33_P3285047 0.1382 0.5179
SRP007169 ZNF75A 7627 RNAseq 0.2010 0.6637
SRP008496 ZNF75A 7627 RNAseq 0.3994 0.2184
SRP064894 ZNF75A 7627 RNAseq 0.1568 0.4543
SRP133303 ZNF75A 7627 RNAseq 0.3634 0.0600
SRP159526 ZNF75A 7627 RNAseq 0.2016 0.5810
SRP193095 ZNF75A 7627 RNAseq 0.3874 0.0001
SRP219564 ZNF75A 7627 RNAseq 0.3301 0.2950
TCGA ZNF75A 7627 RNAseq 0.0665 0.4248

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ZNF75A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZNF75A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF75A 7627 5 5 20
GSE20123 ZNF75A 7627 5 4 21
GSE43470 ZNF75A 7627 4 7 32
GSE46452 ZNF75A 7627 38 1 20
GSE47630 ZNF75A 7627 13 6 21
GSE54993 ZNF75A 7627 4 5 61
GSE54994 ZNF75A 7627 5 9 39
GSE60625 ZNF75A 7627 4 0 7
GSE74703 ZNF75A 7627 4 5 27
GSE74704 ZNF75A 7627 3 2 15
TCGA ZNF75A 7627 19 13 64

Total number of gains: 104; Total number of losses: 57; Total Number of normals: 327.  

 

Somatic mutations of ZNF75A:

 

Generating mutation plots.

 

Highly correlated genes for ZNF75A:

 

Showing top 20/131 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF75AHAUS20.79263303
ZNF75AZNF1210.765373303
ZNF75APRKCI0.751442303
ZNF75AZCCHC20.746878303
ZNF75AZNF1400.743464303
ZNF75ADONSON0.73518303
ZNF75APWP10.721724303
ZNF75ADDX590.716533403
ZNF75ACDC42SE10.712827303
ZNF75AEIF2B50.709657303
ZNF75AHSD17B70.707138303
ZNF75ANAA250.706384303
ZNF75ATHAP50.703893303
ZNF75ALRRC340.696956303
ZNF75ALMLN0.695828403
ZNF75ATMEM1810.694794303
ZNF75AWDR700.692874303
ZNF75AGPATCH10.686044303
ZNF75AC6orf470.685844303
ZNF75ALTV10.678327403

For details and further investigation, click here