ZNF256

 

Full name: zinc finger protein 256 Alias Symbol: BMZF-3
Type: protein-coding gene Cytoband: 19q13
Entrez ID: 10172 HGNC ID: HGNC:13049 Ensembl Gene: ENSG00000152454 OMIM ID: 606956
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of ZNF256:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF256 10172 223714_at 0.0788 0.9628
GSE26886 ZNF256 10172 223714_at -0.6858 0.0246
GSE45670 ZNF256 10172 223714_at -0.6453 0.0421
GSE53622 ZNF256 10172 25632 -0.6329 0.0000
GSE53624 ZNF256 10172 25632 -0.2439 0.0764
GSE63941 ZNF256 10172 223714_at -0.5104 0.6207
GSE77861 ZNF256 10172 223714_at -0.0483 0.8267
GSE97050 ZNF256 10172 A_23_P16022 -0.8936 0.0894
SRP064894 ZNF256 10172 RNAseq -0.5911 0.0374
SRP133303 ZNF256 10172 RNAseq -0.3109 0.4198
SRP159526 ZNF256 10172 RNAseq -0.2407 0.7548
SRP193095 ZNF256 10172 RNAseq -0.2996 0.2355
SRP219564 ZNF256 10172 RNAseq -0.6003 0.3268
TCGA ZNF256 10172 RNAseq -0.1138 0.5892

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ZNF256 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF256:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF256 10172 2 4 24
GSE20123 ZNF256 10172 2 3 25
GSE43470 ZNF256 10172 3 9 31
GSE46452 ZNF256 10172 45 1 13
GSE47630 ZNF256 10172 8 6 26
GSE54993 ZNF256 10172 18 4 48
GSE54994 ZNF256 10172 5 12 36
GSE60625 ZNF256 10172 9 0 2
GSE74703 ZNF256 10172 3 6 27
GSE74704 ZNF256 10172 2 1 17
TCGA ZNF256 10172 20 15 61

Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.  


 

Somatic mutations of ZNF256:

 

Generating mutation plots.

 

Highly correlated genes for ZNF256:

 

Showing top 20/134 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF256ZNF320.789234303
ZNF256ZNF2340.787244303
ZNF256ZNF5650.780664303
ZNF256MRPL20.780149303
ZNF256LSM14A0.767384303
ZNF256LYRM10.735918303
ZNF256METTL140.730637303
ZNF256NDUFS30.727581303
ZNF256TBL1X0.726803303
ZNF256PPP1R110.726069303
ZNF256PEX190.723853303
ZNF256TRIM380.713039303
ZNF256TAF110.707093303
ZNF256ZNF2080.704264303
ZNF256UBP10.700137403
ZNF256ZNF5670.696962403
ZNF256AMOTL10.694886303
ZNF256PLD60.692309303
ZNF256CGGBP10.691633303
ZNF256MED230.68842303

For details and further investigation, click here