| Full name: tRNA methyltransferase 44 homolog | Alias Symbol: FLJ35725|TRM44 | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 152992 | HGNC ID: HGNC:26653 | Ensembl Gene: ENSG00000155275 | OMIM ID: 614309 |
| Drug and gene relationship at DGIdb | |||
Expression of TRMT44:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMT44 | 152992 | 1554192_s_at | -0.0308 | 0.9448 | |
| GSE20347 | TRMT44 | 152992 | 220891_at | 0.0594 | 0.3397 | |
| GSE23400 | TRMT44 | 152992 | 220891_at | -0.0010 | 0.9640 | |
| GSE26886 | TRMT44 | 152992 | 1554192_s_at | -0.0409 | 0.7492 | |
| GSE29001 | TRMT44 | 152992 | 220891_at | 0.0187 | 0.9104 | |
| GSE38129 | TRMT44 | 152992 | 220891_at | -0.0180 | 0.7584 | |
| GSE45670 | TRMT44 | 152992 | 1554192_s_at | -0.1158 | 0.2547 | |
| GSE53622 | TRMT44 | 152992 | 61585 | -0.5771 | 0.0000 | |
| GSE53624 | TRMT44 | 152992 | 61585 | -0.7663 | 0.0000 | |
| GSE63941 | TRMT44 | 152992 | 1554192_s_at | 0.5032 | 0.0107 | |
| GSE77861 | TRMT44 | 152992 | 235097_at | -0.2428 | 0.0962 | |
| SRP007169 | TRMT44 | 152992 | RNAseq | -1.4110 | 0.0005 | |
| SRP008496 | TRMT44 | 152992 | RNAseq | -1.4917 | 0.0000 | |
| SRP064894 | TRMT44 | 152992 | RNAseq | -0.8282 | 0.0000 | |
| SRP133303 | TRMT44 | 152992 | RNAseq | -0.7829 | 0.0000 | |
| SRP159526 | TRMT44 | 152992 | RNAseq | -0.4731 | 0.0643 | |
| SRP193095 | TRMT44 | 152992 | RNAseq | -0.6956 | 0.0000 | |
| SRP219564 | TRMT44 | 152992 | RNAseq | -0.8011 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TRMT44 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TRMT44:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMT44 | 152992 | 0 | 18 | 12 | |
| GSE20123 | TRMT44 | 152992 | 0 | 18 | 12 | |
| GSE43470 | TRMT44 | 152992 | 0 | 17 | 26 | |
| GSE46452 | TRMT44 | 152992 | 1 | 36 | 22 | |
| GSE47630 | TRMT44 | 152992 | 1 | 19 | 20 | |
| GSE54993 | TRMT44 | 152992 | 10 | 0 | 60 | |
| GSE54994 | TRMT44 | 152992 | 3 | 12 | 38 | |
| GSE60625 | TRMT44 | 152992 | 0 | 0 | 11 | |
| GSE74703 | TRMT44 | 152992 | 0 | 13 | 23 | |
| GSE74704 | TRMT44 | 152992 | 0 | 10 | 10 | |
| TCGA | TRMT44 | 152992 | 9 | 47 | 40 |
Total number of gains: 24; Total number of losses: 190; Total Number of normals: 274.
Somatic mutations of TRMT44:
Generating mutation plots.
Highly correlated genes for TRMT44:
Showing top 20/327 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMT44 | NR2F6 | 0.675299 | 3 | 0 | 3 |
| TRMT44 | ARSF | 0.662112 | 4 | 0 | 4 |
| TRMT44 | LNX1 | 0.660086 | 3 | 0 | 3 |
| TRMT44 | ATP13A4 | 0.647326 | 3 | 0 | 3 |
| TRMT44 | CHCHD5 | 0.640245 | 3 | 0 | 3 |
| TRMT44 | CMTM1 | 0.639672 | 3 | 0 | 3 |
| TRMT44 | CLINT1 | 0.63043 | 4 | 0 | 4 |
| TRMT44 | CAPN14 | 0.629226 | 4 | 0 | 4 |
| TRMT44 | TEKT5 | 0.626935 | 3 | 0 | 3 |
| TRMT44 | LIN54 | 0.625712 | 3 | 0 | 3 |
| TRMT44 | ACOX3 | 0.624315 | 5 | 0 | 5 |
| TRMT44 | AGFG2 | 0.623311 | 4 | 0 | 4 |
| TRMT44 | ITGAD | 0.619263 | 3 | 0 | 3 |
| TRMT44 | CEACAM7 | 0.619213 | 3 | 0 | 3 |
| TRMT44 | RAB11A | 0.618867 | 4 | 0 | 4 |
| TRMT44 | CEACAM1 | 0.613332 | 5 | 0 | 5 |
| TRMT44 | MPP7 | 0.611899 | 4 | 0 | 4 |
| TRMT44 | ANKRD18B | 0.610774 | 4 | 0 | 3 |
| TRMT44 | SCNN1B | 0.606093 | 4 | 0 | 3 |
| TRMT44 | TEX101 | 0.60604 | 4 | 0 | 3 |
For details and further investigation, click here
