| Full name: acyl-CoA oxidase 3, pristanoyl | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 8310 | HGNC ID: HGNC:121 | Ensembl Gene: ENSG00000087008 | OMIM ID: 603402 |
| Drug and gene relationship at DGIdb | |||
ACOX3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway | |
| hsa04024 | cAMP signaling pathway |
Expression of ACOX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACOX3 | 8310 | 204241_at | -0.3152 | 0.8002 | |
| GSE20347 | ACOX3 | 8310 | 204242_s_at | -1.2416 | 0.0000 | |
| GSE23400 | ACOX3 | 8310 | 204242_s_at | -0.6116 | 0.0000 | |
| GSE26886 | ACOX3 | 8310 | 204241_at | -2.2493 | 0.0000 | |
| GSE29001 | ACOX3 | 8310 | 204241_at | -1.8229 | 0.0000 | |
| GSE38129 | ACOX3 | 8310 | 204242_s_at | -1.1137 | 0.0000 | |
| GSE45670 | ACOX3 | 8310 | 204241_at | -0.7313 | 0.0323 | |
| GSE53622 | ACOX3 | 8310 | 105055 | -1.7471 | 0.0000 | |
| GSE53624 | ACOX3 | 8310 | 105055 | -1.8613 | 0.0000 | |
| GSE63941 | ACOX3 | 8310 | 204242_s_at | -0.1195 | 0.7199 | |
| GSE77861 | ACOX3 | 8310 | 204242_s_at | -0.6760 | 0.0002 | |
| GSE97050 | ACOX3 | 8310 | A_23_P316381 | -1.4255 | 0.0555 | |
| SRP007169 | ACOX3 | 8310 | RNAseq | -2.9089 | 0.0000 | |
| SRP008496 | ACOX3 | 8310 | RNAseq | -2.8741 | 0.0000 | |
| SRP064894 | ACOX3 | 8310 | RNAseq | -1.3702 | 0.0000 | |
| SRP133303 | ACOX3 | 8310 | RNAseq | -1.6715 | 0.0000 | |
| SRP159526 | ACOX3 | 8310 | RNAseq | -2.0071 | 0.0000 | |
| SRP193095 | ACOX3 | 8310 | RNAseq | -1.6245 | 0.0000 | |
| SRP219564 | ACOX3 | 8310 | RNAseq | -1.2775 | 0.0012 | |
| TCGA | ACOX3 | 8310 | RNAseq | -0.3548 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by ACOX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACOX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACOX3 | 8310 | 0 | 18 | 12 | |
| GSE20123 | ACOX3 | 8310 | 0 | 18 | 12 | |
| GSE43470 | ACOX3 | 8310 | 0 | 17 | 26 | |
| GSE46452 | ACOX3 | 8310 | 1 | 36 | 22 | |
| GSE47630 | ACOX3 | 8310 | 1 | 19 | 20 | |
| GSE54993 | ACOX3 | 8310 | 10 | 0 | 60 | |
| GSE54994 | ACOX3 | 8310 | 3 | 12 | 38 | |
| GSE60625 | ACOX3 | 8310 | 0 | 0 | 11 | |
| GSE74703 | ACOX3 | 8310 | 0 | 13 | 23 | |
| GSE74704 | ACOX3 | 8310 | 0 | 10 | 10 | |
| TCGA | ACOX3 | 8310 | 9 | 47 | 40 |
Total number of gains: 24; Total number of losses: 190; Total Number of normals: 274.
Somatic mutations of ACOX3:
Generating mutation plots.
Highly correlated genes for ACOX3:
Showing top 20/1847 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACOX3 | SORT1 | 0.860374 | 10 | 0 | 10 |
| ACOX3 | HPGD | 0.854391 | 10 | 0 | 10 |
| ACOX3 | ACAA1 | 0.850672 | 9 | 0 | 9 |
| ACOX3 | CXCR2 | 0.841778 | 10 | 0 | 10 |
| ACOX3 | GPD1L | 0.840696 | 10 | 0 | 10 |
| ACOX3 | RMND5B | 0.838537 | 11 | 0 | 11 |
| ACOX3 | RNF141 | 0.83651 | 10 | 0 | 10 |
| ACOX3 | NFIA | 0.833978 | 6 | 0 | 6 |
| ACOX3 | CYP2J2 | 0.830331 | 10 | 0 | 10 |
| ACOX3 | ENDOU | 0.825046 | 10 | 0 | 10 |
| ACOX3 | CLCA4 | 0.8243 | 9 | 0 | 9 |
| ACOX3 | C5orf66-AS1 | 0.823586 | 5 | 0 | 5 |
| ACOX3 | MGLL | 0.823581 | 10 | 0 | 10 |
| ACOX3 | MGST2 | 0.822252 | 10 | 0 | 10 |
| ACOX3 | PPP1R3C | 0.822156 | 10 | 0 | 10 |
| ACOX3 | EIF4E3 | 0.820998 | 6 | 0 | 6 |
| ACOX3 | SNORA68 | 0.820278 | 3 | 0 | 3 |
| ACOX3 | SH3BGRL2 | 0.818342 | 6 | 0 | 6 |
| ACOX3 | PCBP1-AS1 | 0.818227 | 3 | 0 | 3 |
| ACOX3 | ALDH9A1 | 0.810763 | 11 | 0 | 11 |
For details and further investigation, click here
