| Full name: coiled-coil-helix-coiled-coil-helix domain containing 5 | Alias Symbol: MGC11104|MIC14|MIX14 | ||
| Type: protein-coding gene | Cytoband: 2q14.1 | ||
| Entrez ID: 84269 | HGNC ID: HGNC:17840 | Ensembl Gene: ENSG00000125611 | OMIM ID: 616978 |
| Drug and gene relationship at DGIdb | |||
Expression of CHCHD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHCHD5 | 84269 | 223479_s_at | 0.0996 | 0.7916 | |
| GSE26886 | CHCHD5 | 84269 | 223479_s_at | 0.4339 | 0.0534 | |
| GSE45670 | CHCHD5 | 84269 | 223479_s_at | 0.1149 | 0.6494 | |
| GSE53622 | CHCHD5 | 84269 | 62734 | 0.1141 | 0.1186 | |
| GSE53624 | CHCHD5 | 84269 | 62734 | 0.1018 | 0.1545 | |
| GSE63941 | CHCHD5 | 84269 | 223479_s_at | 1.6229 | 0.0003 | |
| GSE77861 | CHCHD5 | 84269 | 237993_at | -0.1416 | 0.3077 | |
| GSE97050 | CHCHD5 | 84269 | A_24_P379727 | 0.2809 | 0.2734 | |
| SRP007169 | CHCHD5 | 84269 | RNAseq | -0.6748 | 0.2236 | |
| SRP008496 | CHCHD5 | 84269 | RNAseq | -0.4960 | 0.1518 | |
| SRP064894 | CHCHD5 | 84269 | RNAseq | 0.3207 | 0.3967 | |
| SRP133303 | CHCHD5 | 84269 | RNAseq | -0.2575 | 0.0666 | |
| SRP159526 | CHCHD5 | 84269 | RNAseq | -0.0077 | 0.9826 | |
| SRP193095 | CHCHD5 | 84269 | RNAseq | -0.3037 | 0.0349 | |
| SRP219564 | CHCHD5 | 84269 | RNAseq | -0.2764 | 0.4664 | |
| TCGA | CHCHD5 | 84269 | RNAseq | 0.0286 | 0.7505 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CHCHD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHCHD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHCHD5 | 84269 | 6 | 2 | 22 | |
| GSE20123 | CHCHD5 | 84269 | 6 | 2 | 22 | |
| GSE43470 | CHCHD5 | 84269 | 3 | 1 | 39 | |
| GSE46452 | CHCHD5 | 84269 | 1 | 4 | 54 | |
| GSE47630 | CHCHD5 | 84269 | 7 | 0 | 33 | |
| GSE54993 | CHCHD5 | 84269 | 0 | 6 | 64 | |
| GSE54994 | CHCHD5 | 84269 | 10 | 0 | 43 | |
| GSE60625 | CHCHD5 | 84269 | 0 | 3 | 8 | |
| GSE74703 | CHCHD5 | 84269 | 3 | 1 | 32 | |
| GSE74704 | CHCHD5 | 84269 | 3 | 2 | 15 | |
| TCGA | CHCHD5 | 84269 | 31 | 6 | 59 |
Total number of gains: 70; Total number of losses: 27; Total Number of normals: 391.
Somatic mutations of CHCHD5:
Generating mutation plots.
Highly correlated genes for CHCHD5:
Showing top 20/547 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHCHD5 | RPP38 | 0.86229 | 3 | 0 | 3 |
| CHCHD5 | PRPS2 | 0.776842 | 3 | 0 | 3 |
| CHCHD5 | PTPN9 | 0.768731 | 3 | 0 | 3 |
| CHCHD5 | EARS2 | 0.761745 | 3 | 0 | 3 |
| CHCHD5 | USP3 | 0.757025 | 3 | 0 | 3 |
| CHCHD5 | POLA1 | 0.752601 | 3 | 0 | 3 |
| CHCHD5 | SF3B4 | 0.741589 | 3 | 0 | 3 |
| CHCHD5 | SLC25A40 | 0.733397 | 3 | 0 | 3 |
| CHCHD5 | CTCF | 0.730832 | 4 | 0 | 3 |
| CHCHD5 | BUB3 | 0.730754 | 3 | 0 | 3 |
| CHCHD5 | INPP5B | 0.728253 | 3 | 0 | 3 |
| CHCHD5 | FBXL19 | 0.726525 | 3 | 0 | 3 |
| CHCHD5 | FAM192A | 0.719266 | 3 | 0 | 3 |
| CHCHD5 | UBR7 | 0.717965 | 3 | 0 | 3 |
| CHCHD5 | SEMA4A | 0.715328 | 3 | 0 | 3 |
| CHCHD5 | KLHL11 | 0.713689 | 3 | 0 | 3 |
| CHCHD5 | FBRS | 0.711729 | 4 | 0 | 3 |
| CHCHD5 | LGALS8 | 0.71077 | 3 | 0 | 3 |
| CHCHD5 | UBE2N | 0.710416 | 3 | 0 | 3 |
| CHCHD5 | CELSR2 | 0.709174 | 3 | 0 | 3 |
For details and further investigation, click here
