| Full name: RAB11A, member RAS oncogene family | Alias Symbol: YL8 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 8766 | HGNC ID: HGNC:9760 | Ensembl Gene: ENSG00000103769 | OMIM ID: 605570 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RAB11A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB11A | 8766 | 200863_s_at | -0.8895 | 0.2074 | |
| GSE20347 | RAB11A | 8766 | 200863_s_at | -1.4412 | 0.0000 | |
| GSE23400 | RAB11A | 8766 | 200863_s_at | -1.1975 | 0.0000 | |
| GSE26886 | RAB11A | 8766 | 200863_s_at | -1.4958 | 0.0000 | |
| GSE29001 | RAB11A | 8766 | 200863_s_at | -1.1930 | 0.0001 | |
| GSE38129 | RAB11A | 8766 | 200863_s_at | -0.9869 | 0.0000 | |
| GSE45670 | RAB11A | 8766 | 200863_s_at | -0.5674 | 0.0105 | |
| GSE53622 | RAB11A | 8766 | 35817 | -1.2471 | 0.0000 | |
| GSE53624 | RAB11A | 8766 | 35817 | -1.6119 | 0.0000 | |
| GSE63941 | RAB11A | 8766 | 200863_s_at | 0.4283 | 0.1529 | |
| GSE77861 | RAB11A | 8766 | 200863_s_at | -1.0197 | 0.0047 | |
| GSE97050 | RAB11A | 8766 | A_23_P77145 | -0.9427 | 0.1116 | |
| SRP007169 | RAB11A | 8766 | RNAseq | -2.4702 | 0.0000 | |
| SRP008496 | RAB11A | 8766 | RNAseq | -2.2609 | 0.0000 | |
| SRP064894 | RAB11A | 8766 | RNAseq | -1.7936 | 0.0000 | |
| SRP133303 | RAB11A | 8766 | RNAseq | -1.3067 | 0.0000 | |
| SRP159526 | RAB11A | 8766 | RNAseq | -1.8133 | 0.0000 | |
| SRP193095 | RAB11A | 8766 | RNAseq | -1.6510 | 0.0000 | |
| SRP219564 | RAB11A | 8766 | RNAseq | -1.6763 | 0.0001 | |
| TCGA | RAB11A | 8766 | RNAseq | -0.1152 | 0.0189 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by RAB11A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB11A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB11A | 8766 | 6 | 4 | 20 | |
| GSE20123 | RAB11A | 8766 | 6 | 4 | 20 | |
| GSE43470 | RAB11A | 8766 | 4 | 6 | 33 | |
| GSE46452 | RAB11A | 8766 | 3 | 7 | 49 | |
| GSE47630 | RAB11A | 8766 | 8 | 10 | 22 | |
| GSE54993 | RAB11A | 8766 | 5 | 6 | 59 | |
| GSE54994 | RAB11A | 8766 | 6 | 7 | 40 | |
| GSE60625 | RAB11A | 8766 | 4 | 0 | 7 | |
| GSE74703 | RAB11A | 8766 | 4 | 3 | 29 | |
| GSE74704 | RAB11A | 8766 | 3 | 3 | 14 | |
| TCGA | RAB11A | 8766 | 9 | 16 | 71 |
Total number of gains: 58; Total number of losses: 66; Total Number of normals: 364.
Somatic mutations of RAB11A:
Generating mutation plots.
Highly correlated genes for RAB11A:
Showing top 20/1965 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB11A | IL1RN | 0.867235 | 10 | 0 | 10 |
| RAB11A | ECM1 | 0.863298 | 10 | 0 | 10 |
| RAB11A | SPINK5 | 0.861698 | 10 | 0 | 10 |
| RAB11A | SCEL | 0.861551 | 11 | 0 | 11 |
| RAB11A | CLIC3 | 0.859781 | 9 | 0 | 8 |
| RAB11A | TJP1 | 0.859416 | 11 | 0 | 11 |
| RAB11A | SPINK7 | 0.858599 | 6 | 0 | 6 |
| RAB11A | TAB3 | 0.858455 | 7 | 0 | 7 |
| RAB11A | GLTP | 0.857015 | 9 | 0 | 9 |
| RAB11A | ACAA1 | 0.854487 | 8 | 0 | 8 |
| RAB11A | EMP1 | 0.853579 | 10 | 0 | 10 |
| RAB11A | C18orf25 | 0.853425 | 11 | 0 | 11 |
| RAB11A | FCHO2 | 0.850241 | 7 | 0 | 7 |
| RAB11A | MPP7 | 0.85014 | 7 | 0 | 7 |
| RAB11A | USP6NL | 0.847654 | 11 | 0 | 11 |
| RAB11A | CES2 | 0.847605 | 8 | 0 | 8 |
| RAB11A | ANXA1 | 0.84691 | 10 | 0 | 10 |
| RAB11A | GBP6 | 0.845991 | 4 | 0 | 4 |
| RAB11A | UBL3 | 0.845836 | 10 | 0 | 10 |
| RAB11A | ABLIM1 | 0.845438 | 11 | 0 | 11 |
For details and further investigation, click here
