| Full name: nuclear receptor subfamily 2 group F member 6 | Alias Symbol: EAR-2|EAR2 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 2063 | HGNC ID: HGNC:7977 | Ensembl Gene: ENSG00000160113 | OMIM ID: 132880 |
| Drug and gene relationship at DGIdb | |||
Expression of NR2F6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR2F6 | 2063 | 209262_s_at | 0.4473 | 0.5301 | |
| GSE20347 | NR2F6 | 2063 | 209262_s_at | -0.3266 | 0.0588 | |
| GSE23400 | NR2F6 | 2063 | 209262_s_at | -0.2661 | 0.0001 | |
| GSE26886 | NR2F6 | 2063 | 209262_s_at | -0.2396 | 0.1341 | |
| GSE29001 | NR2F6 | 2063 | 209262_s_at | -0.3040 | 0.1062 | |
| GSE38129 | NR2F6 | 2063 | 209262_s_at | -0.1360 | 0.3949 | |
| GSE45670 | NR2F6 | 2063 | 209262_s_at | 0.0610 | 0.7118 | |
| GSE53622 | NR2F6 | 2063 | 98515 | -0.9160 | 0.0000 | |
| GSE53624 | NR2F6 | 2063 | 98515 | -0.4103 | 0.0000 | |
| GSE63941 | NR2F6 | 2063 | 209262_s_at | 0.2732 | 0.4508 | |
| GSE77861 | NR2F6 | 2063 | 209262_s_at | -0.0870 | 0.7418 | |
| GSE97050 | NR2F6 | 2063 | A_33_P3403132 | -0.1630 | 0.5688 | |
| SRP007169 | NR2F6 | 2063 | RNAseq | -1.8041 | 0.0005 | |
| SRP008496 | NR2F6 | 2063 | RNAseq | -1.7069 | 0.0000 | |
| SRP064894 | NR2F6 | 2063 | RNAseq | 0.0562 | 0.8781 | |
| SRP133303 | NR2F6 | 2063 | RNAseq | -0.6307 | 0.0240 | |
| SRP159526 | NR2F6 | 2063 | RNAseq | -0.3981 | 0.1245 | |
| SRP193095 | NR2F6 | 2063 | RNAseq | -0.9786 | 0.0000 | |
| SRP219564 | NR2F6 | 2063 | RNAseq | -0.1983 | 0.5723 | |
| TCGA | NR2F6 | 2063 | RNAseq | -0.1804 | 0.0032 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NR2F6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR2F6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR2F6 | 2063 | 4 | 4 | 22 | |
| GSE20123 | NR2F6 | 2063 | 3 | 2 | 25 | |
| GSE43470 | NR2F6 | 2063 | 2 | 6 | 35 | |
| GSE46452 | NR2F6 | 2063 | 47 | 1 | 11 | |
| GSE47630 | NR2F6 | 2063 | 4 | 8 | 28 | |
| GSE54993 | NR2F6 | 2063 | 15 | 4 | 51 | |
| GSE54994 | NR2F6 | 2063 | 6 | 14 | 33 | |
| GSE60625 | NR2F6 | 2063 | 9 | 0 | 2 | |
| GSE74703 | NR2F6 | 2063 | 2 | 4 | 30 | |
| GSE74704 | NR2F6 | 2063 | 0 | 2 | 18 | |
| TCGA | NR2F6 | 2063 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of NR2F6:
Generating mutation plots.
Highly correlated genes for NR2F6:
Showing top 20/591 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR2F6 | PUS10 | 0.795445 | 3 | 0 | 3 |
| NR2F6 | YIPF3 | 0.773479 | 3 | 0 | 3 |
| NR2F6 | ZNF432 | 0.755363 | 3 | 0 | 3 |
| NR2F6 | GPR108 | 0.748169 | 3 | 0 | 3 |
| NR2F6 | CDC37 | 0.747243 | 3 | 0 | 3 |
| NR2F6 | C19orf18 | 0.746478 | 3 | 0 | 3 |
| NR2F6 | TBC1D22B | 0.742116 | 4 | 0 | 3 |
| NR2F6 | GPATCH1 | 0.735389 | 3 | 0 | 3 |
| NR2F6 | SLC35A2 | 0.731132 | 4 | 0 | 4 |
| NR2F6 | AARS2 | 0.730385 | 3 | 0 | 3 |
| NR2F6 | RAD18 | 0.730256 | 3 | 0 | 3 |
| NR2F6 | MTIF3 | 0.72983 | 3 | 0 | 3 |
| NR2F6 | VPS25 | 0.728909 | 3 | 0 | 3 |
| NR2F6 | TBCC | 0.724939 | 4 | 0 | 4 |
| NR2F6 | UROS | 0.716009 | 3 | 0 | 3 |
| NR2F6 | DDI2 | 0.707447 | 3 | 0 | 3 |
| NR2F6 | PRDM10 | 0.703492 | 3 | 0 | 3 |
| NR2F6 | ZNF765 | 0.699634 | 4 | 0 | 3 |
| NR2F6 | SMPD1 | 0.698571 | 3 | 0 | 3 |
| NR2F6 | PPP6R1 | 0.694972 | 3 | 0 | 3 |
For details and further investigation, click here
