CAPN14

 

Full name: calpain 14 Alias Symbol: 
Type: protein-coding gene Cytoband: 2p23.1
Entrez ID: 440854 HGNC ID: HGNC:16664 Ensembl Gene: ENSG00000214711 OMIM ID: 610229
Drug and gene relationship at DGIdb

 

Expression of CAPN14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CAPN14 440854 1557321_a_at -4.1349 0.1414
GSE26886 CAPN14 440854 1557321_a_at -7.3843 0.0000
GSE45670 CAPN14 440854 1557321_a_at -2.0910 0.0270
GSE53622 CAPN14 440854 776 -3.9305 0.0000
GSE53624 CAPN14 440854 776 -4.8455 0.0000
GSE63941 CAPN14 440854 1557321_a_at 0.2666 0.1989
GSE77861 CAPN14 440854 1557321_a_at -4.3921 0.0022
SRP007169 CAPN14 440854 RNAseq -7.9785 0.0000
SRP008496 CAPN14 440854 RNAseq -7.5397 0.0000
SRP064894 CAPN14 440854 RNAseq -6.2399 0.0000
SRP133303 CAPN14 440854 RNAseq -4.8594 0.0000
SRP159526 CAPN14 440854 RNAseq -6.6949 0.0000
SRP219564 CAPN14 440854 RNAseq -4.4752 0.0026
TCGA CAPN14 440854 RNAseq -0.1597 0.7391

Upregulated datasets: 0; Downregulated datasets: 11.  

 

Survival by CAPN14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CAPN14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CAPN14 440854 10 1 19
GSE20123 CAPN14 440854 9 1 20
GSE43470 CAPN14 440854 2 1 40
GSE46452 CAPN14 440854 2 4 53
GSE47630 CAPN14 440854 8 0 32
GSE54993 CAPN14 440854 0 5 65
GSE54994 CAPN14 440854 10 0 43
GSE60625 CAPN14 440854 0 3 8
GSE74703 CAPN14 440854 2 0 34
GSE74704 CAPN14 440854 9 1 10
TCGA CAPN14 440854 36 2 58

Total number of gains: 88; Total number of losses: 18; Total Number of normals: 382.  

 

Somatic mutations of CAPN14:

 

Generating mutation plots.

 

Highly correlated genes for CAPN14:

 

Showing top 20/1512 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CAPN14CYSRT10.927616606
CAPN14PRSS270.919518707
CAPN14TMPRSS11B0.913044707
CAPN14CLCA40.908452707
CAPN14CRNN0.904927707
CAPN14SPINK50.897461707
CAPN14SCEL0.894246707
CAPN14VSIG10L0.893659606
CAPN14MUC210.891594303
CAPN14ENDOU0.888878606
CAPN14TMOD30.882085606
CAPN14SLC16A60.880593606
CAPN14TMPRSS11E0.879235606
CAPN14CXCR20.875696606
CAPN14KRT780.874808707
CAPN14EPS8L20.868285606
CAPN14IL36A0.86667606
CAPN14RANBP90.866249606
CAPN14IKZF20.862067606
CAPN14MPP70.860385606

For details and further investigation, click here