| Full name: ArfGAP with FG repeats 2 | Alias Symbol: RABR | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 3268 | HGNC ID: HGNC:5177 | Ensembl Gene: ENSG00000106351 | OMIM ID: 604019 |
| Drug and gene relationship at DGIdb | |||
Expression of AGFG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGFG2 | 3268 | 222126_at | -0.7953 | 0.1410 | |
| GSE20347 | AGFG2 | 3268 | 222362_at | -1.6379 | 0.0000 | |
| GSE23400 | AGFG2 | 3268 | 222362_at | -1.2444 | 0.0000 | |
| GSE26886 | AGFG2 | 3268 | 222126_at | -1.7215 | 0.0000 | |
| GSE29001 | AGFG2 | 3268 | 222126_at | -1.4336 | 0.0000 | |
| GSE38129 | AGFG2 | 3268 | 222126_at | -0.9477 | 0.0000 | |
| GSE45670 | AGFG2 | 3268 | 222126_at | -0.7920 | 0.0049 | |
| GSE53622 | AGFG2 | 3268 | 54983 | -2.0189 | 0.0000 | |
| GSE53624 | AGFG2 | 3268 | 54983 | -1.8329 | 0.0000 | |
| GSE63941 | AGFG2 | 3268 | 222126_at | 0.1570 | 0.7172 | |
| GSE77861 | AGFG2 | 3268 | 222126_at | -1.1173 | 0.0000 | |
| GSE97050 | AGFG2 | 3268 | A_23_P311640 | -1.2561 | 0.0750 | |
| SRP007169 | AGFG2 | 3268 | RNAseq | -4.8829 | 0.0000 | |
| SRP008496 | AGFG2 | 3268 | RNAseq | -4.4137 | 0.0000 | |
| SRP064894 | AGFG2 | 3268 | RNAseq | -2.5987 | 0.0000 | |
| SRP133303 | AGFG2 | 3268 | RNAseq | -2.6154 | 0.0000 | |
| SRP159526 | AGFG2 | 3268 | RNAseq | -2.6469 | 0.0000 | |
| SRP193095 | AGFG2 | 3268 | RNAseq | -2.0660 | 0.0000 | |
| SRP219564 | AGFG2 | 3268 | RNAseq | -1.7584 | 0.0024 | |
| TCGA | AGFG2 | 3268 | RNAseq | -0.3267 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by AGFG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGFG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGFG2 | 3268 | 13 | 0 | 17 | |
| GSE20123 | AGFG2 | 3268 | 13 | 0 | 17 | |
| GSE43470 | AGFG2 | 3268 | 7 | 2 | 34 | |
| GSE46452 | AGFG2 | 3268 | 11 | 1 | 47 | |
| GSE47630 | AGFG2 | 3268 | 7 | 3 | 30 | |
| GSE54993 | AGFG2 | 3268 | 1 | 9 | 60 | |
| GSE54994 | AGFG2 | 3268 | 16 | 3 | 34 | |
| GSE60625 | AGFG2 | 3268 | 0 | 0 | 11 | |
| GSE74703 | AGFG2 | 3268 | 7 | 1 | 28 | |
| GSE74704 | AGFG2 | 3268 | 9 | 0 | 11 | |
| TCGA | AGFG2 | 3268 | 53 | 6 | 37 |
Total number of gains: 137; Total number of losses: 25; Total Number of normals: 326.
Somatic mutations of AGFG2:
Generating mutation plots.
Highly correlated genes for AGFG2:
Showing top 20/1828 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGFG2 | FAM3D | 0.854332 | 7 | 0 | 7 |
| AGFG2 | CRISP3 | 0.842779 | 11 | 0 | 11 |
| AGFG2 | C5orf66-AS1 | 0.840095 | 6 | 0 | 6 |
| AGFG2 | MGLL | 0.83231 | 11 | 0 | 11 |
| AGFG2 | SASH1 | 0.830466 | 11 | 0 | 11 |
| AGFG2 | SNORA68 | 0.829696 | 4 | 0 | 4 |
| AGFG2 | EHD3 | 0.826435 | 11 | 0 | 11 |
| AGFG2 | GCHFR | 0.824654 | 8 | 0 | 8 |
| AGFG2 | ENDOU | 0.821673 | 11 | 0 | 11 |
| AGFG2 | RMND5B | 0.820471 | 11 | 0 | 11 |
| AGFG2 | GYS2 | 0.819275 | 10 | 0 | 10 |
| AGFG2 | SPNS2 | 0.818726 | 5 | 0 | 5 |
| AGFG2 | TTC9 | 0.817944 | 11 | 0 | 11 |
| AGFG2 | PHACTR4 | 0.817258 | 11 | 0 | 11 |
| AGFG2 | SFTA2 | 0.817051 | 4 | 0 | 4 |
| AGFG2 | ABLIM1 | 0.816632 | 11 | 0 | 11 |
| AGFG2 | VAT1 | 0.806538 | 11 | 0 | 11 |
| AGFG2 | FAM214A | 0.806238 | 6 | 0 | 6 |
| AGFG2 | ACOX3 | 0.805474 | 10 | 0 | 10 |
| AGFG2 | SH3BGRL2 | 0.803614 | 8 | 0 | 7 |
For details and further investigation, click here
