| Full name: carcinoembryonic antigen related cell adhesion molecule 7 | Alias Symbol: CEA | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 1087 | HGNC ID: HGNC:1819 | Ensembl Gene: ENSG00000007306 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CEACAM7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEACAM7 | 1087 | 206199_at | -4.1017 | 0.0702 | |
| GSE20347 | CEACAM7 | 1087 | 206199_at | -4.1887 | 0.0000 | |
| GSE23400 | CEACAM7 | 1087 | 206199_at | -2.7338 | 0.0000 | |
| GSE26886 | CEACAM7 | 1087 | 206199_at | -8.0202 | 0.0000 | |
| GSE29001 | CEACAM7 | 1087 | 206199_at | -3.7723 | 0.0001 | |
| GSE38129 | CEACAM7 | 1087 | 206199_at | -3.4380 | 0.0000 | |
| GSE45670 | CEACAM7 | 1087 | 206199_at | -0.1915 | 0.8773 | |
| GSE53622 | CEACAM7 | 1087 | 59919 | -2.8815 | 0.0000 | |
| GSE53624 | CEACAM7 | 1087 | 59919 | -3.7732 | 0.0000 | |
| GSE63941 | CEACAM7 | 1087 | 211848_s_at | 0.0983 | 0.8055 | |
| GSE77861 | CEACAM7 | 1087 | 206199_at | -3.8247 | 0.0097 | |
| GSE97050 | CEACAM7 | 1087 | A_24_P228302 | -0.3813 | 0.6479 | |
| SRP007169 | CEACAM7 | 1087 | RNAseq | -6.0182 | 0.0305 | |
| SRP008496 | CEACAM7 | 1087 | RNAseq | -7.9114 | 0.0000 | |
| SRP064894 | CEACAM7 | 1087 | RNAseq | -4.7694 | 0.0000 | |
| SRP133303 | CEACAM7 | 1087 | RNAseq | -4.8808 | 0.0000 | |
| SRP159526 | CEACAM7 | 1087 | RNAseq | -5.0029 | 0.0000 | |
| SRP193095 | CEACAM7 | 1087 | RNAseq | -2.7416 | 0.0006 | |
| TCGA | CEACAM7 | 1087 | RNAseq | -0.1277 | 0.8568 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by CEACAM7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEACAM7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEACAM7 | 1087 | 4 | 4 | 22 | |
| GSE20123 | CEACAM7 | 1087 | 4 | 3 | 23 | |
| GSE43470 | CEACAM7 | 1087 | 3 | 11 | 29 | |
| GSE46452 | CEACAM7 | 1087 | 48 | 1 | 10 | |
| GSE47630 | CEACAM7 | 1087 | 9 | 5 | 26 | |
| GSE54993 | CEACAM7 | 1087 | 17 | 4 | 49 | |
| GSE54994 | CEACAM7 | 1087 | 7 | 12 | 34 | |
| GSE60625 | CEACAM7 | 1087 | 9 | 0 | 2 | |
| GSE74703 | CEACAM7 | 1087 | 3 | 7 | 26 | |
| GSE74704 | CEACAM7 | 1087 | 4 | 1 | 15 | |
| TCGA | CEACAM7 | 1087 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 64; Total Number of normals: 302.
Somatic mutations of CEACAM7:
Generating mutation plots.
Highly correlated genes for CEACAM7:
Showing top 20/1237 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEACAM7 | TMPRSS11E | 0.877476 | 11 | 0 | 11 |
| CEACAM7 | CYSRT1 | 0.868893 | 6 | 0 | 6 |
| CEACAM7 | CEACAM5 | 0.866159 | 13 | 0 | 13 |
| CEACAM7 | PRSS27 | 0.86597 | 8 | 0 | 8 |
| CEACAM7 | CEACAM1 | 0.860095 | 12 | 0 | 11 |
| CEACAM7 | OTOP3 | 0.858897 | 3 | 0 | 3 |
| CEACAM7 | CLCA4 | 0.855979 | 12 | 0 | 12 |
| CEACAM7 | VSIG10L | 0.851483 | 7 | 0 | 7 |
| CEACAM7 | GDPD3 | 0.846874 | 11 | 0 | 11 |
| CEACAM7 | TMPRSS11A | 0.841251 | 4 | 0 | 4 |
| CEACAM7 | TPRG1 | 0.840648 | 6 | 0 | 6 |
| CEACAM7 | IL36A | 0.84033 | 11 | 0 | 11 |
| CEACAM7 | CAPN14 | 0.838982 | 7 | 0 | 7 |
| CEACAM7 | SLURP1 | 0.838804 | 12 | 0 | 12 |
| CEACAM7 | CRNN | 0.836932 | 12 | 0 | 12 |
| CEACAM7 | SPINK5 | 0.836305 | 12 | 0 | 11 |
| CEACAM7 | CXCR2 | 0.835015 | 10 | 0 | 10 |
| CEACAM7 | KLK13 | 0.833145 | 13 | 0 | 13 |
| CEACAM7 | CEACAM6 | 0.830883 | 13 | 0 | 12 |
| CEACAM7 | SLC13A4 | 0.827786 | 11 | 0 | 11 |
For details and further investigation, click here
