| Full name: tRNA phosphotransferase 1 | Alias Symbol: MGC11134 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 83707 | HGNC ID: HGNC:20316 | Ensembl Gene: ENSG00000149743 | OMIM ID: 610470 |
| Drug and gene relationship at DGIdb | |||
Expression of TRPT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRPT1 | 83707 | 223436_s_at | -0.2148 | 0.3227 | |
| GSE26886 | TRPT1 | 83707 | 223436_s_at | 0.3696 | 0.0667 | |
| GSE45670 | TRPT1 | 83707 | 223436_s_at | -0.0897 | 0.5458 | |
| GSE53622 | TRPT1 | 83707 | 88666 | -0.0904 | 0.2235 | |
| GSE53624 | TRPT1 | 83707 | 88666 | -0.0805 | 0.2219 | |
| GSE63941 | TRPT1 | 83707 | 223436_s_at | 0.7391 | 0.1296 | |
| GSE77861 | TRPT1 | 83707 | 223436_s_at | -0.2399 | 0.2439 | |
| GSE97050 | TRPT1 | A_21_P0000027 | -0.0463 | 0.8352 | ||
| SRP007169 | TRPT1 | 83707 | RNAseq | -1.2834 | 0.0017 | |
| SRP008496 | TRPT1 | 83707 | RNAseq | -0.8465 | 0.0013 | |
| SRP064894 | TRPT1 | 83707 | RNAseq | 0.0070 | 0.9770 | |
| SRP133303 | TRPT1 | 83707 | RNAseq | -0.3921 | 0.0622 | |
| SRP159526 | TRPT1 | 83707 | RNAseq | -0.1173 | 0.6566 | |
| SRP193095 | TRPT1 | 83707 | RNAseq | -0.4414 | 0.0000 | |
| SRP219564 | TRPT1 | 83707 | RNAseq | -0.2809 | 0.2293 | |
| TCGA | TRPT1 | 83707 | RNAseq | -0.1300 | 0.0478 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRPT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRPT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRPT1 | 83707 | 6 | 5 | 19 | |
| GSE20123 | TRPT1 | 83707 | 6 | 5 | 19 | |
| GSE43470 | TRPT1 | 83707 | 1 | 3 | 39 | |
| GSE46452 | TRPT1 | 83707 | 8 | 4 | 47 | |
| GSE47630 | TRPT1 | 83707 | 3 | 7 | 30 | |
| GSE54993 | TRPT1 | 83707 | 3 | 0 | 67 | |
| GSE54994 | TRPT1 | 83707 | 5 | 5 | 43 | |
| GSE60625 | TRPT1 | 83707 | 0 | 4 | 7 | |
| GSE74703 | TRPT1 | 83707 | 1 | 1 | 34 | |
| GSE74704 | TRPT1 | 83707 | 4 | 3 | 13 | |
| TCGA | TRPT1 | 83707 | 19 | 10 | 67 |
Total number of gains: 56; Total number of losses: 47; Total Number of normals: 385.
Somatic mutations of TRPT1:
Generating mutation plots.
Highly correlated genes for TRPT1:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRPT1 | PPP2R5A | 0.694494 | 3 | 0 | 3 |
| TRPT1 | LMNTD2 | 0.686464 | 3 | 0 | 3 |
| TRPT1 | RNF208 | 0.67997 | 3 | 0 | 3 |
| TRPT1 | IQCH | 0.649841 | 3 | 0 | 3 |
| TRPT1 | TALDO1 | 0.646062 | 3 | 0 | 3 |
| TRPT1 | FBF1 | 0.63337 | 3 | 0 | 3 |
| TRPT1 | PRDX5 | 0.63116 | 6 | 0 | 5 |
| TRPT1 | YPEL3 | 0.62856 | 3 | 0 | 3 |
| TRPT1 | TOM1L1 | 0.615546 | 3 | 0 | 3 |
| TRPT1 | NDUFAF3 | 0.611067 | 4 | 0 | 4 |
| TRPT1 | NANOS2 | 0.607446 | 4 | 0 | 3 |
| TRPT1 | NDOR1 | 0.603191 | 4 | 0 | 3 |
| TRPT1 | B3GALT4 | 0.60194 | 3 | 0 | 3 |
| TRPT1 | MAGIX | 0.595393 | 4 | 0 | 3 |
| TRPT1 | NUDT22 | 0.590336 | 9 | 0 | 7 |
| TRPT1 | RMND5B | 0.580183 | 3 | 0 | 3 |
| TRPT1 | ZNHIT2 | 0.573346 | 4 | 0 | 3 |
| TRPT1 | GPR137 | 0.573109 | 5 | 0 | 4 |
| TRPT1 | SLC37A1 | 0.572609 | 3 | 0 | 3 |
| TRPT1 | COX8A | 0.567298 | 7 | 0 | 6 |
For details and further investigation, click here
