| Full name: G protein-coupled receptor 137 | Alias Symbol: C11orf4|GPR137A|TM7SF1L1 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 56834 | HGNC ID: HGNC:24300 | Ensembl Gene: ENSG00000173264 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GPR137:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR137 | 56834 | 221966_at | -0.0728 | 0.8569 | |
| GSE20347 | GPR137 | 56834 | 221966_at | -0.1477 | 0.0973 | |
| GSE23400 | GPR137 | 56834 | 221966_at | -0.1011 | 0.0139 | |
| GSE26886 | GPR137 | 56834 | 43934_at | -0.4043 | 0.0003 | |
| GSE29001 | GPR137 | 56834 | 221966_at | -0.2428 | 0.0778 | |
| GSE38129 | GPR137 | 56834 | 221966_at | -0.1555 | 0.0409 | |
| GSE45670 | GPR137 | 56834 | 43934_at | -0.0466 | 0.6433 | |
| GSE53622 | GPR137 | 56834 | 2817 | -0.2235 | 0.0050 | |
| GSE53624 | GPR137 | 56834 | 2817 | 0.1570 | 0.0139 | |
| GSE63941 | GPR137 | 56834 | 221966_at | 0.3949 | 0.1173 | |
| GSE77861 | GPR137 | 56834 | 221966_at | -0.1100 | 0.6093 | |
| GSE97050 | GPR137 | 56834 | A_23_P416686 | 0.3033 | 0.3554 | |
| SRP007169 | GPR137 | 56834 | RNAseq | -1.7943 | 0.0000 | |
| SRP008496 | GPR137 | 56834 | RNAseq | -1.3029 | 0.0000 | |
| SRP064894 | GPR137 | 56834 | RNAseq | 0.1853 | 0.5023 | |
| SRP133303 | GPR137 | 56834 | RNAseq | -0.1110 | 0.6163 | |
| SRP159526 | GPR137 | 56834 | RNAseq | 0.2462 | 0.3531 | |
| SRP193095 | GPR137 | 56834 | RNAseq | -0.1347 | 0.2259 | |
| SRP219564 | GPR137 | 56834 | RNAseq | 0.1178 | 0.6549 | |
| TCGA | GPR137 | 56834 | RNAseq | -0.0801 | 0.1615 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GPR137 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR137:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR137 | 56834 | 6 | 5 | 19 | |
| GSE20123 | GPR137 | 56834 | 6 | 5 | 19 | |
| GSE43470 | GPR137 | 56834 | 1 | 3 | 39 | |
| GSE46452 | GPR137 | 56834 | 8 | 4 | 47 | |
| GSE47630 | GPR137 | 56834 | 4 | 6 | 30 | |
| GSE54993 | GPR137 | 56834 | 3 | 0 | 67 | |
| GSE54994 | GPR137 | 56834 | 5 | 5 | 43 | |
| GSE60625 | GPR137 | 56834 | 0 | 4 | 7 | |
| GSE74703 | GPR137 | 56834 | 1 | 1 | 34 | |
| GSE74704 | GPR137 | 56834 | 4 | 3 | 13 | |
| TCGA | GPR137 | 56834 | 20 | 9 | 67 |
Total number of gains: 58; Total number of losses: 45; Total Number of normals: 385.
Somatic mutations of GPR137:
Generating mutation plots.
Highly correlated genes for GPR137:
Showing top 20/453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR137 | TBC1D21 | 0.696911 | 3 | 0 | 3 |
| GPR137 | CYP2S1 | 0.678911 | 3 | 0 | 3 |
| GPR137 | HAVCR1 | 0.67006 | 3 | 0 | 3 |
| GPR137 | CAPN1 | 0.666387 | 8 | 0 | 6 |
| GPR137 | ST3GAL3 | 0.663122 | 3 | 0 | 3 |
| GPR137 | PCSK7 | 0.655243 | 5 | 0 | 4 |
| GPR137 | STARD5 | 0.651805 | 5 | 0 | 4 |
| GPR137 | MCC | 0.646911 | 3 | 0 | 3 |
| GPR137 | RAB4B | 0.646684 | 6 | 0 | 5 |
| GPR137 | EPHB1 | 0.645618 | 3 | 0 | 3 |
| GPR137 | ZSCAN20 | 0.643749 | 3 | 0 | 3 |
| GPR137 | MUC5AC | 0.643088 | 5 | 0 | 4 |
| GPR137 | JUP | 0.639211 | 6 | 0 | 5 |
| GPR137 | TUFM | 0.638239 | 3 | 0 | 3 |
| GPR137 | ATP12A | 0.638083 | 3 | 0 | 3 |
| GPR137 | SLC27A4 | 0.637604 | 5 | 0 | 5 |
| GPR137 | SLC35A4 | 0.632351 | 4 | 0 | 3 |
| GPR137 | ENPP3 | 0.627387 | 3 | 0 | 3 |
| GPR137 | BMP15 | 0.625831 | 6 | 0 | 5 |
| GPR137 | MLST8 | 0.625479 | 4 | 0 | 3 |
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