| Full name: NADH:ubiquinone oxidoreductase complex assembly factor 3 | Alias Symbol: MGC10527|DKFZP564J0123|E3-3|2P1 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 25915 | HGNC ID: HGNC:29918 | Ensembl Gene: ENSG00000178057 | OMIM ID: 612911 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFAF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFAF3 | 25915 | 209177_at | -0.0725 | 0.7660 | |
| GSE20347 | NDUFAF3 | 25915 | 209177_at | -0.4365 | 0.0008 | |
| GSE23400 | NDUFAF3 | 25915 | 209177_at | -0.0676 | 0.3106 | |
| GSE26886 | NDUFAF3 | 25915 | 209177_at | 0.2986 | 0.0676 | |
| GSE29001 | NDUFAF3 | 25915 | 209177_at | -0.3498 | 0.1096 | |
| GSE38129 | NDUFAF3 | 25915 | 209177_at | -0.4266 | 0.0002 | |
| GSE45670 | NDUFAF3 | 25915 | 209177_at | -0.3376 | 0.0209 | |
| GSE53622 | NDUFAF3 | 25915 | 50419 | -0.1931 | 0.0001 | |
| GSE53624 | NDUFAF3 | 25915 | 50419 | -0.1249 | 0.0218 | |
| GSE63941 | NDUFAF3 | 25915 | 209177_at | -0.5251 | 0.2052 | |
| GSE77861 | NDUFAF3 | 25915 | 209177_at | -0.2147 | 0.2943 | |
| GSE97050 | NDUFAF3 | 25915 | A_23_P256172 | -0.1370 | 0.5634 | |
| SRP007169 | NDUFAF3 | 25915 | RNAseq | -0.6754 | 0.0360 | |
| SRP008496 | NDUFAF3 | 25915 | RNAseq | -0.6697 | 0.0083 | |
| SRP064894 | NDUFAF3 | 25915 | RNAseq | -0.1104 | 0.7093 | |
| SRP133303 | NDUFAF3 | 25915 | RNAseq | -0.4238 | 0.0032 | |
| SRP159526 | NDUFAF3 | 25915 | RNAseq | -0.2827 | 0.1311 | |
| SRP193095 | NDUFAF3 | 25915 | RNAseq | -0.4572 | 0.0014 | |
| SRP219564 | NDUFAF3 | 25915 | RNAseq | -0.4589 | 0.1558 | |
| TCGA | NDUFAF3 | 25915 | RNAseq | -0.0815 | 0.1895 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFAF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFAF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFAF3 | 25915 | 0 | 18 | 12 | |
| GSE20123 | NDUFAF3 | 25915 | 0 | 19 | 11 | |
| GSE43470 | NDUFAF3 | 25915 | 0 | 18 | 25 | |
| GSE46452 | NDUFAF3 | 25915 | 2 | 16 | 41 | |
| GSE47630 | NDUFAF3 | 25915 | 1 | 24 | 15 | |
| GSE54993 | NDUFAF3 | 25915 | 6 | 2 | 62 | |
| GSE54994 | NDUFAF3 | 25915 | 0 | 36 | 17 | |
| GSE60625 | NDUFAF3 | 25915 | 5 | 0 | 6 | |
| GSE74703 | NDUFAF3 | 25915 | 0 | 14 | 22 | |
| GSE74704 | NDUFAF3 | 25915 | 0 | 12 | 8 | |
| TCGA | NDUFAF3 | 25915 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of NDUFAF3:
Generating mutation plots.
Highly correlated genes for NDUFAF3:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFAF3 | GH2 | 0.800152 | 3 | 0 | 3 |
| NDUFAF3 | POU6F1 | 0.766254 | 3 | 0 | 3 |
| NDUFAF3 | TUBB4B | 0.752528 | 3 | 0 | 3 |
| NDUFAF3 | LRTOMT | 0.735438 | 3 | 0 | 3 |
| NDUFAF3 | GBA2 | 0.727933 | 3 | 0 | 3 |
| NDUFAF3 | TBC1D17 | 0.726905 | 3 | 0 | 3 |
| NDUFAF3 | CACHD1 | 0.694475 | 3 | 0 | 3 |
| NDUFAF3 | TBC1D20 | 0.689349 | 3 | 0 | 3 |
| NDUFAF3 | LCN10 | 0.684121 | 3 | 0 | 3 |
| NDUFAF3 | PGAP2 | 0.669779 | 3 | 0 | 3 |
| NDUFAF3 | KLHL9 | 0.667763 | 3 | 0 | 3 |
| NDUFAF3 | USP19 | 0.665332 | 6 | 0 | 5 |
| NDUFAF3 | MAP2K2 | 0.663491 | 4 | 0 | 3 |
| NDUFAF3 | TMEM18 | 0.661296 | 3 | 0 | 3 |
| NDUFAF3 | F8 | 0.655618 | 3 | 0 | 3 |
| NDUFAF3 | DENND5B | 0.651715 | 4 | 0 | 3 |
| NDUFAF3 | SNAP29 | 0.651434 | 4 | 0 | 3 |
| NDUFAF3 | YIPF3 | 0.649779 | 4 | 0 | 3 |
| NDUFAF3 | PRKACA | 0.649382 | 4 | 0 | 3 |
| NDUFAF3 | FAM120AOS | 0.648585 | 4 | 0 | 3 |
For details and further investigation, click here
