| Full name: IQ motif containing H | Alias Symbol: FLJ12476 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 64799 | HGNC ID: HGNC:25721 | Ensembl Gene: ENSG00000103599 | OMIM ID: 612523 |
| Drug and gene relationship at DGIdb | |||
Expression of IQCH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IQCH | 64799 | 239812_s_at | 0.0452 | 0.8796 | |
| GSE20347 | IQCH | 64799 | 220361_at | 0.1508 | 0.1016 | |
| GSE23400 | IQCH | 64799 | 220361_at | 0.0209 | 0.3641 | |
| GSE26886 | IQCH | 64799 | 224165_s_at | 0.7366 | 0.0004 | |
| GSE29001 | IQCH | 64799 | 220361_at | 0.2041 | 0.2732 | |
| GSE38129 | IQCH | 64799 | 220361_at | 0.2055 | 0.0062 | |
| GSE45670 | IQCH | 64799 | 220361_at | 0.2850 | 0.0159 | |
| GSE53622 | IQCH | 64799 | 50392 | 0.6795 | 0.0000 | |
| GSE53624 | IQCH | 64799 | 50392 | 0.7676 | 0.0000 | |
| GSE63941 | IQCH | 64799 | 239812_s_at | 1.0748 | 0.0477 | |
| GSE77861 | IQCH | 64799 | 239813_at | -0.0583 | 0.6022 | |
| GSE97050 | IQCH | 64799 | A_33_P3227631 | 0.0782 | 0.6849 | |
| SRP007169 | IQCH | 64799 | RNAseq | 0.6054 | 0.4687 | |
| SRP133303 | IQCH | 64799 | RNAseq | 0.5582 | 0.0170 | |
| SRP159526 | IQCH | 64799 | RNAseq | 0.9890 | 0.0295 | |
| SRP193095 | IQCH | 64799 | RNAseq | 0.2045 | 0.1461 | |
| SRP219564 | IQCH | 64799 | RNAseq | -0.3683 | 0.3941 | |
| TCGA | IQCH | 64799 | RNAseq | 0.2865 | 0.0766 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IQCH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IQCH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IQCH | 64799 | 8 | 1 | 21 | |
| GSE20123 | IQCH | 64799 | 8 | 1 | 21 | |
| GSE43470 | IQCH | 64799 | 4 | 6 | 33 | |
| GSE46452 | IQCH | 64799 | 3 | 7 | 49 | |
| GSE47630 | IQCH | 64799 | 8 | 10 | 22 | |
| GSE54993 | IQCH | 64799 | 5 | 6 | 59 | |
| GSE54994 | IQCH | 64799 | 6 | 7 | 40 | |
| GSE60625 | IQCH | 64799 | 4 | 0 | 7 | |
| GSE74703 | IQCH | 64799 | 4 | 3 | 29 | |
| GSE74704 | IQCH | 64799 | 3 | 1 | 16 | |
| TCGA | IQCH | 64799 | 10 | 15 | 71 |
Total number of gains: 63; Total number of losses: 57; Total Number of normals: 368.
Somatic mutations of IQCH:
Generating mutation plots.
Highly correlated genes for IQCH:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IQCH | PEX11G | 0.824261 | 3 | 0 | 3 |
| IQCH | OLIG3 | 0.763685 | 3 | 0 | 3 |
| IQCH | ZNF620 | 0.740629 | 3 | 0 | 3 |
| IQCH | FAM181A | 0.738512 | 3 | 0 | 3 |
| IQCH | CALML6 | 0.72862 | 3 | 0 | 3 |
| IQCH | NXF3 | 0.713653 | 3 | 0 | 3 |
| IQCH | NAT14 | 0.710929 | 4 | 0 | 4 |
| IQCH | SLC5A10 | 0.692275 | 3 | 0 | 3 |
| IQCH | ABCC6 | 0.690618 | 3 | 0 | 3 |
| IQCH | DRD4 | 0.682884 | 4 | 0 | 4 |
| IQCH | FOXL2 | 0.679707 | 4 | 0 | 3 |
| IQCH | FGG | 0.676342 | 3 | 0 | 3 |
| IQCH | LRFN3 | 0.673702 | 4 | 0 | 3 |
| IQCH | TFF1 | 0.673612 | 3 | 0 | 3 |
| IQCH | MEP1B | 0.67129 | 3 | 0 | 3 |
| IQCH | CAPN13 | 0.667731 | 3 | 0 | 3 |
| IQCH | PLA2G4F | 0.666908 | 4 | 0 | 3 |
| IQCH | RCOR2 | 0.666895 | 5 | 0 | 3 |
| IQCH | RASL10B | 0.665103 | 4 | 0 | 3 |
| IQCH | CHGB | 0.663728 | 3 | 0 | 3 |
For details and further investigation, click here
