| Full name: nanos C2HC-type zinc finger 2 | Alias Symbol: NOS2|ZC2HC12B | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 339345 | HGNC ID: HGNC:23292 | Ensembl Gene: | OMIM ID: 608228 |
| Drug and gene relationship at DGIdb | |||
Expression of NANOS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NANOS2 | 339345 | 1557767_at | -0.1105 | 0.6252 | |
| GSE26886 | NANOS2 | 339345 | 1557767_at | -0.0088 | 0.9529 | |
| GSE45670 | NANOS2 | 339345 | 1557767_at | 0.0111 | 0.9266 | |
| GSE53622 | NANOS2 | 339345 | 15906 | -2.2890 | 0.0000 | |
| GSE53624 | NANOS2 | 339345 | 15906 | -2.0904 | 0.0000 | |
| GSE63941 | NANOS2 | 339345 | 1557767_at | 0.2206 | 0.0366 | |
| GSE77861 | NANOS2 | 339345 | 1557767_at | -0.0801 | 0.5400 | |
| GSE97050 | NANOS2 | 339345 | A_33_P3388453 | -0.7788 | 0.1159 | |
| TCGA | NANOS2 | 339345 | RNAseq | 1.0949 | 0.5169 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NANOS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NANOS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NANOS2 | 339345 | 4 | 5 | 21 | |
| GSE20123 | NANOS2 | 339345 | 4 | 4 | 22 | |
| GSE43470 | NANOS2 | 339345 | 3 | 11 | 29 | |
| GSE46452 | NANOS2 | 339345 | 45 | 1 | 13 | |
| GSE47630 | NANOS2 | 339345 | 8 | 7 | 25 | |
| GSE54993 | NANOS2 | 339345 | 17 | 4 | 49 | |
| GSE54994 | NANOS2 | 339345 | 5 | 13 | 35 | |
| GSE60625 | NANOS2 | 339345 | 9 | 0 | 2 | |
| GSE74703 | NANOS2 | 339345 | 3 | 7 | 26 | |
| GSE74704 | NANOS2 | 339345 | 4 | 2 | 14 | |
| TCGA | NANOS2 | 339345 | 16 | 15 | 65 |
Total number of gains: 118; Total number of losses: 69; Total Number of normals: 301.
Somatic mutations of NANOS2:
Generating mutation plots.
Highly correlated genes for NANOS2:
Showing top 20/733 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NANOS2 | KRTAP20-1 | 0.914917 | 3 | 0 | 3 |
| NANOS2 | OR2Z1 | 0.875419 | 3 | 0 | 3 |
| NANOS2 | FAM163B | 0.86296 | 3 | 0 | 3 |
| NANOS2 | NCCRP1 | 0.850842 | 3 | 0 | 3 |
| NANOS2 | ARID5A | 0.826216 | 3 | 0 | 3 |
| NANOS2 | TECPR1 | 0.813198 | 3 | 0 | 3 |
| NANOS2 | OTOP3 | 0.808706 | 3 | 0 | 3 |
| NANOS2 | MUC22 | 0.807839 | 3 | 0 | 3 |
| NANOS2 | CD164L2 | 0.788455 | 3 | 0 | 3 |
| NANOS2 | RAET1E | 0.788124 | 4 | 0 | 4 |
| NANOS2 | TEN1 | 0.787898 | 3 | 0 | 3 |
| NANOS2 | GPX6 | 0.785551 | 3 | 0 | 3 |
| NANOS2 | CYP3A7 | 0.778611 | 3 | 0 | 3 |
| NANOS2 | PLEKHN1 | 0.777992 | 4 | 0 | 4 |
| NANOS2 | KPRP | 0.777878 | 3 | 0 | 3 |
| NANOS2 | DUSP5 | 0.775281 | 3 | 0 | 3 |
| NANOS2 | ALOX12 | 0.767232 | 3 | 0 | 3 |
| NANOS2 | CRB1 | 0.766989 | 3 | 0 | 3 |
| NANOS2 | TMOD3 | 0.764152 | 3 | 0 | 3 |
| NANOS2 | ATG9B | 0.763639 | 3 | 0 | 3 |
For details and further investigation, click here
