ZNHIT2

 

Full name: zinc finger HIT-type containing 2 Alias Symbol: FON
Type: protein-coding gene Cytoband: 11q13.1
Entrez ID: 741 HGNC ID: HGNC:1177 Ensembl Gene: ENSG00000174276 OMIM ID: 604575
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ZNHIT2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNHIT2 741 219050_s_at 0.5717 0.0967
GSE20347 ZNHIT2 741 219050_s_at 0.0775 0.5994
GSE23400 ZNHIT2 741 219050_s_at -0.0104 0.8039
GSE26886 ZNHIT2 741 219050_s_at 0.9105 0.0000
GSE29001 ZNHIT2 741 219050_s_at 0.1342 0.4775
GSE38129 ZNHIT2 741 219050_s_at 0.1854 0.1124
GSE45670 ZNHIT2 741 219050_s_at 0.3754 0.0093
GSE53622 ZNHIT2 741 20849 0.1456 0.1881
GSE53624 ZNHIT2 741 20849 0.4638 0.0000
GSE63941 ZNHIT2 741 219050_s_at 0.8578 0.1025
GSE77861 ZNHIT2 741 219050_s_at 0.0709 0.6203
GSE97050 ZNHIT2 741 A_33_P3213747 -0.1544 0.7273
SRP007169 ZNHIT2 741 RNAseq -0.3984 0.3582
SRP008496 ZNHIT2 741 RNAseq -0.1391 0.6732
SRP064894 ZNHIT2 741 RNAseq 0.6070 0.0880
SRP133303 ZNHIT2 741 RNAseq 0.3060 0.2108
SRP159526 ZNHIT2 741 RNAseq 0.4187 0.1012
SRP193095 ZNHIT2 741 RNAseq 0.3279 0.0134
SRP219564 ZNHIT2 741 RNAseq 0.2272 0.5000
TCGA ZNHIT2 741 RNAseq 0.0143 0.9758

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ZNHIT2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZNHIT2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNHIT2 741 7 6 17
GSE20123 ZNHIT2 741 7 6 17
GSE43470 ZNHIT2 741 2 3 38
GSE46452 ZNHIT2 741 11 3 45
GSE47630 ZNHIT2 741 5 6 29
GSE54993 ZNHIT2 741 3 0 67
GSE54994 ZNHIT2 741 6 5 42
GSE60625 ZNHIT2 741 0 3 8
GSE74703 ZNHIT2 741 2 1 33
GSE74704 ZNHIT2 741 5 4 11
TCGA ZNHIT2 741 23 7 66

Total number of gains: 71; Total number of losses: 44; Total Number of normals: 373.  

 

Somatic mutations of ZNHIT2:

 

Generating mutation plots.

 

Highly correlated genes for ZNHIT2:

 

Showing top 20/1097 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNHIT2C3orf330.730311303
ZNHIT2ARHGEF190.72941404
ZNHIT2AGMAT0.719263404
ZNHIT2MRPL470.714101505
ZNHIT2E4F10.712875505
ZNHIT2NIPA20.704849303
ZNHIT2C12orf570.701398303
ZNHIT2ACBD60.697533403
ZNHIT2NFKB20.695443303
ZNHIT2LTBR0.691051504
ZNHIT2SAAL10.689434404
ZNHIT2DDX550.688667404
ZNHIT2EAF20.68838303
ZNHIT2ALG100.68741303
ZNHIT2CHAMP10.686083403
ZNHIT2ATRIP0.6844303
ZNHIT2TBRG40.684075505
ZNHIT2ZNF4880.682796403
ZNHIT2KNTC10.681806403
ZNHIT2PPP1R9B0.680291403

For details and further investigation, click here