| Full name: protein phosphatase 2 regulatory subunit B'alpha | Alias Symbol: PR61A|B56A|B56alpha | ||
| Type: protein-coding gene | Cytoband: 1q32.3 | ||
| Entrez ID: 5525 | HGNC ID: HGNC:9309 | Ensembl Gene: ENSG00000066027 | OMIM ID: 601643 |
| Drug and gene relationship at DGIdb | |||
PPP2R5A involved pathways:
Expression of PPP2R5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2R5A | 5525 | 202187_s_at | -0.5783 | 0.1198 | |
| GSE20347 | PPP2R5A | 5525 | 202187_s_at | -0.6668 | 0.0001 | |
| GSE23400 | PPP2R5A | 5525 | 202187_s_at | -0.4944 | 0.0000 | |
| GSE26886 | PPP2R5A | 5525 | 202187_s_at | -0.8252 | 0.0011 | |
| GSE29001 | PPP2R5A | 5525 | 202187_s_at | -0.7880 | 0.0065 | |
| GSE38129 | PPP2R5A | 5525 | 202187_s_at | -0.6070 | 0.0000 | |
| GSE45670 | PPP2R5A | 5525 | 202187_s_at | -0.3960 | 0.0141 | |
| GSE53622 | PPP2R5A | 5525 | 77295 | -0.7422 | 0.0000 | |
| GSE53624 | PPP2R5A | 5525 | 77295 | -0.9052 | 0.0000 | |
| GSE63941 | PPP2R5A | 5525 | 202187_s_at | 0.4651 | 0.4419 | |
| GSE77861 | PPP2R5A | 5525 | 202187_s_at | -0.3924 | 0.1041 | |
| GSE97050 | PPP2R5A | 5525 | A_24_P251221 | -0.5915 | 0.1156 | |
| SRP007169 | PPP2R5A | 5525 | RNAseq | -0.7755 | 0.0220 | |
| SRP008496 | PPP2R5A | 5525 | RNAseq | -0.7645 | 0.0055 | |
| SRP064894 | PPP2R5A | 5525 | RNAseq | -0.9623 | 0.0000 | |
| SRP133303 | PPP2R5A | 5525 | RNAseq | -0.6176 | 0.0007 | |
| SRP159526 | PPP2R5A | 5525 | RNAseq | -0.3724 | 0.4648 | |
| SRP193095 | PPP2R5A | 5525 | RNAseq | -0.8179 | 0.0000 | |
| SRP219564 | PPP2R5A | 5525 | RNAseq | -1.0022 | 0.0011 | |
| TCGA | PPP2R5A | 5525 | RNAseq | -0.1759 | 0.0022 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PPP2R5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP2R5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2R5A | 5525 | 10 | 0 | 20 | |
| GSE20123 | PPP2R5A | 5525 | 10 | 0 | 20 | |
| GSE43470 | PPP2R5A | 5525 | 7 | 1 | 35 | |
| GSE46452 | PPP2R5A | 5525 | 3 | 1 | 55 | |
| GSE47630 | PPP2R5A | 5525 | 15 | 0 | 25 | |
| GSE54993 | PPP2R5A | 5525 | 0 | 6 | 64 | |
| GSE54994 | PPP2R5A | 5525 | 13 | 0 | 40 | |
| GSE60625 | PPP2R5A | 5525 | 0 | 0 | 11 | |
| GSE74703 | PPP2R5A | 5525 | 7 | 1 | 28 | |
| GSE74704 | PPP2R5A | 5525 | 4 | 0 | 16 | |
| TCGA | PPP2R5A | 5525 | 45 | 3 | 48 |
Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.
Somatic mutations of PPP2R5A:
Generating mutation plots.
Highly correlated genes for PPP2R5A:
Showing top 20/1084 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2R5A | CCNYL1 | 0.717689 | 4 | 0 | 4 |
| PPP2R5A | MEGF9 | 0.695452 | 11 | 0 | 10 |
| PPP2R5A | TRPT1 | 0.694494 | 3 | 0 | 3 |
| PPP2R5A | SAMD5 | 0.693392 | 7 | 0 | 6 |
| PPP2R5A | ALDH3A2 | 0.689405 | 12 | 0 | 11 |
| PPP2R5A | VDAC2 | 0.689292 | 8 | 0 | 8 |
| PPP2R5A | TBC1D20 | 0.685895 | 3 | 0 | 3 |
| PPP2R5A | CHP1 | 0.684345 | 9 | 0 | 9 |
| PPP2R5A | ZNF185 | 0.680422 | 11 | 0 | 11 |
| PPP2R5A | ZNF823 | 0.674281 | 6 | 0 | 5 |
| PPP2R5A | TMEM246 | 0.673175 | 9 | 0 | 8 |
| PPP2R5A | EPB41L4A | 0.673157 | 9 | 0 | 9 |
| PPP2R5A | MMEL1 | 0.671642 | 3 | 0 | 3 |
| PPP2R5A | DUOXA1 | 0.66976 | 4 | 0 | 3 |
| PPP2R5A | SLC25A51 | 0.667543 | 4 | 0 | 4 |
| PPP2R5A | ACPP | 0.667515 | 11 | 0 | 10 |
| PPP2R5A | ZDHHC3 | 0.667162 | 10 | 0 | 10 |
| PPP2R5A | CSTB | 0.664685 | 11 | 0 | 10 |
| PPP2R5A | LIPH | 0.663329 | 5 | 0 | 5 |
| PPP2R5A | SLC22A15 | 0.662634 | 4 | 0 | 3 |
For details and further investigation, click here
