| Full name: Fas binding factor 1 | Alias Symbol: FLJ00103|FBF-1|KIAA1863|ALB | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 85302 | HGNC ID: HGNC:24674 | Ensembl Gene: ENSG00000188878 | OMIM ID: 616807 |
| Drug and gene relationship at DGIdb | |||
Expression of FBF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBF1 | 85302 | 1555288_s_at | -0.2634 | 0.2941 | |
| GSE26886 | FBF1 | 85302 | 1555288_s_at | -0.2018 | 0.1751 | |
| GSE45670 | FBF1 | 85302 | 1555288_s_at | 0.0396 | 0.8224 | |
| GSE53622 | FBF1 | 85302 | 103636 | 0.0544 | 0.6103 | |
| GSE53624 | FBF1 | 85302 | 103636 | 0.4086 | 0.0000 | |
| GSE63941 | FBF1 | 85302 | 1555288_s_at | 0.4047 | 0.1166 | |
| GSE77861 | FBF1 | 85302 | 1555288_s_at | -0.3418 | 0.0111 | |
| GSE97050 | FBF1 | 85302 | A_24_P87458 | 0.1185 | 0.5753 | |
| SRP007169 | FBF1 | 85302 | RNAseq | 0.1709 | 0.7469 | |
| SRP008496 | FBF1 | 85302 | RNAseq | 0.0701 | 0.8394 | |
| SRP064894 | FBF1 | 85302 | RNAseq | 0.4975 | 0.0246 | |
| SRP133303 | FBF1 | 85302 | RNAseq | 0.1597 | 0.6102 | |
| SRP159526 | FBF1 | 85302 | RNAseq | 0.1542 | 0.6890 | |
| SRP193095 | FBF1 | 85302 | RNAseq | 0.1873 | 0.3552 | |
| SRP219564 | FBF1 | 85302 | RNAseq | -0.3605 | 0.2513 | |
| TCGA | FBF1 | 85302 | RNAseq | 0.2751 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBF1 | 85302 | 7 | 2 | 21 | |
| GSE20123 | FBF1 | 85302 | 7 | 2 | 21 | |
| GSE43470 | FBF1 | 85302 | 5 | 3 | 35 | |
| GSE46452 | FBF1 | 85302 | 34 | 0 | 25 | |
| GSE47630 | FBF1 | 85302 | 8 | 1 | 31 | |
| GSE54993 | FBF1 | 85302 | 2 | 5 | 63 | |
| GSE54994 | FBF1 | 85302 | 10 | 4 | 39 | |
| GSE60625 | FBF1 | 85302 | 6 | 0 | 5 | |
| GSE74703 | FBF1 | 85302 | 5 | 1 | 30 | |
| GSE74704 | FBF1 | 85302 | 5 | 1 | 14 | |
| TCGA | FBF1 | 85302 | 31 | 10 | 55 |
Total number of gains: 120; Total number of losses: 29; Total Number of normals: 339.
Somatic mutations of FBF1:
Generating mutation plots.
Highly correlated genes for FBF1:
Showing top 20/123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBF1 | SLC35C1 | 0.808451 | 3 | 0 | 3 |
| FBF1 | FAAH2 | 0.788934 | 3 | 0 | 3 |
| FBF1 | PTPRN | 0.738803 | 3 | 0 | 3 |
| FBF1 | PHLDB3 | 0.733028 | 3 | 0 | 3 |
| FBF1 | TBKBP1 | 0.729851 | 4 | 0 | 3 |
| FBF1 | IQCD | 0.72714 | 3 | 0 | 3 |
| FBF1 | AGPAT2 | 0.722984 | 3 | 0 | 3 |
| FBF1 | A1CF | 0.708496 | 3 | 0 | 3 |
| FBF1 | SLC37A1 | 0.702267 | 4 | 0 | 3 |
| FBF1 | TLCD2 | 0.696057 | 3 | 0 | 3 |
| FBF1 | NRG2 | 0.68987 | 3 | 0 | 3 |
| FBF1 | JMJD8 | 0.689482 | 3 | 0 | 3 |
| FBF1 | OVGP1 | 0.678791 | 3 | 0 | 3 |
| FBF1 | BCKDHA | 0.675618 | 3 | 0 | 3 |
| FBF1 | CRTAC1 | 0.673969 | 4 | 0 | 4 |
| FBF1 | SFTA2 | 0.673067 | 3 | 0 | 3 |
| FBF1 | MC5R | 0.668498 | 3 | 0 | 3 |
| FBF1 | TREH | 0.667355 | 3 | 0 | 3 |
| FBF1 | ABAT | 0.665649 | 4 | 0 | 3 |
| FBF1 | ITGA10 | 0.663535 | 3 | 0 | 3 |
For details and further investigation, click here
