| Full name: tetratricopeptide repeat domain 32 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p24.1 | ||
| Entrez ID: 130502 | HGNC ID: HGNC:32954 | Ensembl Gene: ENSG00000183891 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC32:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC32 | 130502 | 226838_at | 0.1376 | 0.7751 | |
| GSE26886 | TTC32 | 130502 | 226838_at | 1.6432 | 0.0000 | |
| GSE45670 | TTC32 | 130502 | 226838_at | -0.4197 | 0.1979 | |
| GSE53622 | TTC32 | 130502 | 92726 | 0.2999 | 0.0143 | |
| GSE53624 | TTC32 | 130502 | 92726 | 0.3453 | 0.0001 | |
| GSE63941 | TTC32 | 130502 | 226838_at | 1.3024 | 0.0254 | |
| GSE77861 | TTC32 | 130502 | 226838_at | 0.7238 | 0.0556 | |
| GSE97050 | TTC32 | 130502 | A_23_P119857 | 0.0576 | 0.8604 | |
| SRP064894 | TTC32 | 130502 | RNAseq | 0.0750 | 0.7339 | |
| SRP133303 | TTC32 | 130502 | RNAseq | 0.3192 | 0.1614 | |
| SRP159526 | TTC32 | 130502 | RNAseq | 0.6860 | 0.1698 | |
| SRP193095 | TTC32 | 130502 | RNAseq | 0.1299 | 0.4555 | |
| SRP219564 | TTC32 | 130502 | RNAseq | 0.0662 | 0.8606 | |
| TCGA | TTC32 | 130502 | RNAseq | 0.4558 | 0.0003 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TTC32 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC32:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC32 | 130502 | 9 | 2 | 19 | |
| GSE20123 | TTC32 | 130502 | 9 | 2 | 19 | |
| GSE43470 | TTC32 | 130502 | 2 | 0 | 41 | |
| GSE46452 | TTC32 | 130502 | 3 | 4 | 52 | |
| GSE47630 | TTC32 | 130502 | 7 | 0 | 33 | |
| GSE54993 | TTC32 | 130502 | 0 | 7 | 63 | |
| GSE54994 | TTC32 | 130502 | 11 | 0 | 42 | |
| GSE60625 | TTC32 | 130502 | 0 | 3 | 8 | |
| GSE74703 | TTC32 | 130502 | 2 | 0 | 34 | |
| GSE74704 | TTC32 | 130502 | 8 | 2 | 10 | |
| TCGA | TTC32 | 130502 | 36 | 3 | 57 |
Total number of gains: 87; Total number of losses: 23; Total Number of normals: 378.
Somatic mutations of TTC32:
Generating mutation plots.
Highly correlated genes for TTC32:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC32 | EPB41L4B | 0.751734 | 4 | 0 | 4 |
| TTC32 | RAB40B | 0.750361 | 3 | 0 | 3 |
| TTC32 | CHP2 | 0.747402 | 4 | 0 | 4 |
| TTC32 | NPW | 0.740829 | 3 | 0 | 3 |
| TTC32 | PRMT3 | 0.728674 | 3 | 0 | 3 |
| TTC32 | ODC1 | 0.719188 | 3 | 0 | 3 |
| TTC32 | USP27X | 0.713985 | 3 | 0 | 3 |
| TTC32 | MISP | 0.706053 | 3 | 0 | 3 |
| TTC32 | HAUS8 | 0.689429 | 4 | 0 | 3 |
| TTC32 | TIGD7 | 0.686235 | 4 | 0 | 4 |
| TTC32 | ATG4D | 0.674969 | 3 | 0 | 3 |
| TTC32 | FAM189B | 0.672758 | 3 | 0 | 3 |
| TTC32 | ZBTB24 | 0.671364 | 4 | 0 | 3 |
| TTC32 | ZNF526 | 0.670247 | 3 | 0 | 3 |
| TTC32 | ASTN2 | 0.667393 | 3 | 0 | 3 |
| TTC32 | SCLY | 0.666198 | 3 | 0 | 3 |
| TTC32 | RWDD3 | 0.664535 | 3 | 0 | 3 |
| TTC32 | SEC62 | 0.661823 | 4 | 0 | 3 |
| TTC32 | TAS2R14 | 0.656224 | 3 | 0 | 3 |
| TTC32 | ZNF511 | 0.653 | 4 | 0 | 3 |
For details and further investigation, click here
