| Full name: astrotactin 2 | Alias Symbol: KIAA0634 | ||
| Type: protein-coding gene | Cytoband: 9q33.1 | ||
| Entrez ID: 23245 | HGNC ID: HGNC:17021 | Ensembl Gene: ENSG00000148219 | OMIM ID: 612856 |
| Drug and gene relationship at DGIdb | |||
Expression of ASTN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASTN2 | 23245 | 215407_s_at | 0.5373 | 0.5327 | |
| GSE20347 | ASTN2 | 23245 | 209693_at | 0.7644 | 0.0048 | |
| GSE23400 | ASTN2 | 23245 | 215407_s_at | 0.2349 | 0.0043 | |
| GSE26886 | ASTN2 | 23245 | 209693_at | 2.3157 | 0.0002 | |
| GSE29001 | ASTN2 | 23245 | 215407_s_at | 0.9225 | 0.0091 | |
| GSE38129 | ASTN2 | 23245 | 209693_at | 0.7341 | 0.0250 | |
| GSE45670 | ASTN2 | 23245 | 209693_at | 0.7651 | 0.1429 | |
| GSE53622 | ASTN2 | 23245 | 118896 | 0.3316 | 0.0024 | |
| GSE53624 | ASTN2 | 23245 | 118896 | 0.2269 | 0.0188 | |
| GSE63941 | ASTN2 | 23245 | 209693_at | -1.3125 | 0.1546 | |
| GSE77861 | ASTN2 | 23245 | 215407_s_at | 0.5533 | 0.1632 | |
| GSE97050 | ASTN2 | 23245 | A_24_P83738 | 0.1555 | 0.7311 | |
| SRP007169 | ASTN2 | 23245 | RNAseq | 1.6107 | 0.0004 | |
| SRP008496 | ASTN2 | 23245 | RNAseq | 1.6864 | 0.0000 | |
| SRP064894 | ASTN2 | 23245 | RNAseq | 0.8056 | 0.0238 | |
| SRP133303 | ASTN2 | 23245 | RNAseq | 0.5556 | 0.0023 | |
| SRP159526 | ASTN2 | 23245 | RNAseq | 1.7910 | 0.0000 | |
| SRP193095 | ASTN2 | 23245 | RNAseq | 0.5308 | 0.0003 | |
| SRP219564 | ASTN2 | 23245 | RNAseq | -0.2562 | 0.7734 | |
| TCGA | ASTN2 | 23245 | RNAseq | -0.5101 | 0.0648 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ASTN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASTN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASTN2 | 23245 | 4 | 10 | 16 | |
| GSE20123 | ASTN2 | 23245 | 4 | 10 | 16 | |
| GSE43470 | ASTN2 | 23245 | 4 | 3 | 36 | |
| GSE46452 | ASTN2 | 23245 | 6 | 13 | 40 | |
| GSE47630 | ASTN2 | 23245 | 3 | 16 | 21 | |
| GSE54993 | ASTN2 | 23245 | 3 | 3 | 64 | |
| GSE54994 | ASTN2 | 23245 | 9 | 11 | 33 | |
| GSE60625 | ASTN2 | 23245 | 0 | 0 | 11 | |
| GSE74703 | ASTN2 | 23245 | 4 | 3 | 29 | |
| GSE74704 | ASTN2 | 23245 | 2 | 7 | 11 | |
| TCGA | ASTN2 | 23245 | 26 | 24 | 46 |
Total number of gains: 65; Total number of losses: 100; Total Number of normals: 323.
Somatic mutations of ASTN2:
Generating mutation plots.
Highly correlated genes for ASTN2:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASTN2 | NPW | 0.807256 | 3 | 0 | 3 |
| ASTN2 | C10orf91 | 0.738827 | 3 | 0 | 3 |
| ASTN2 | TLR9 | 0.732843 | 3 | 0 | 3 |
| ASTN2 | PLA2G2D | 0.731897 | 3 | 0 | 3 |
| ASTN2 | UFSP1 | 0.718943 | 3 | 0 | 3 |
| ASTN2 | LAYN | 0.709587 | 3 | 0 | 3 |
| ASTN2 | CYP11B1 | 0.709571 | 3 | 0 | 3 |
| ASTN2 | CALML6 | 0.697889 | 4 | 0 | 3 |
| ASTN2 | BSND | 0.693384 | 3 | 0 | 3 |
| ASTN2 | C19orf44 | 0.692977 | 3 | 0 | 3 |
| ASTN2 | LINC01139 | 0.688286 | 3 | 0 | 3 |
| ASTN2 | GNB1L | 0.684028 | 4 | 0 | 4 |
| ASTN2 | FAM181A | 0.683347 | 3 | 0 | 3 |
| ASTN2 | AGPAT1 | 0.671974 | 4 | 0 | 3 |
| ASTN2 | LRRC72 | 0.66824 | 4 | 0 | 4 |
| ASTN2 | TTC32 | 0.667393 | 3 | 0 | 3 |
| ASTN2 | ZDHHC8 | 0.665725 | 3 | 0 | 3 |
| ASTN2 | FBRSL1 | 0.664697 | 4 | 0 | 3 |
| ASTN2 | LOXL3 | 0.662674 | 3 | 0 | 3 |
| ASTN2 | C19orf81 | 0.661984 | 3 | 0 | 3 |
For details and further investigation, click here
