| Full name: HAUS augmin like complex subunit 8 | Alias Symbol: MGC20533|NY-SAR-48 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 93323 | HGNC ID: HGNC:30532 | Ensembl Gene: ENSG00000131351 | OMIM ID: 613434 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HAUS8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAUS8 | 93323 | 226308_at | 0.8208 | 0.0343 | |
| GSE26886 | HAUS8 | 93323 | 226308_at | 0.6879 | 0.0010 | |
| GSE45670 | HAUS8 | 93323 | 226308_at | 0.6556 | 0.0003 | |
| GSE53622 | HAUS8 | 93323 | 68412 | 0.7820 | 0.0000 | |
| GSE53624 | HAUS8 | 93323 | 68412 | 1.0287 | 0.0000 | |
| GSE63941 | HAUS8 | 93323 | 226308_at | 1.2233 | 0.0057 | |
| GSE77861 | HAUS8 | 93323 | 226308_at | 0.7265 | 0.0011 | |
| GSE97050 | HAUS8 | 93323 | A_33_P3242124 | 0.6028 | 0.1897 | |
| SRP007169 | HAUS8 | 93323 | RNAseq | 1.5925 | 0.0202 | |
| SRP064894 | HAUS8 | 93323 | RNAseq | 1.4375 | 0.0000 | |
| SRP133303 | HAUS8 | 93323 | RNAseq | 1.1102 | 0.0001 | |
| SRP159526 | HAUS8 | 93323 | RNAseq | 1.0050 | 0.0077 | |
| SRP193095 | HAUS8 | 93323 | RNAseq | 0.9079 | 0.0000 | |
| SRP219564 | HAUS8 | 93323 | RNAseq | 1.3853 | 0.0000 | |
| TCGA | HAUS8 | 93323 | RNAseq | 0.6092 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by HAUS8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAUS8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAUS8 | 93323 | 4 | 4 | 22 | |
| GSE20123 | HAUS8 | 93323 | 3 | 2 | 25 | |
| GSE43470 | HAUS8 | 93323 | 2 | 6 | 35 | |
| GSE46452 | HAUS8 | 93323 | 47 | 1 | 11 | |
| GSE47630 | HAUS8 | 93323 | 4 | 8 | 28 | |
| GSE54993 | HAUS8 | 93323 | 15 | 4 | 51 | |
| GSE54994 | HAUS8 | 93323 | 6 | 14 | 33 | |
| GSE60625 | HAUS8 | 93323 | 9 | 0 | 2 | |
| GSE74703 | HAUS8 | 93323 | 2 | 4 | 30 | |
| GSE74704 | HAUS8 | 93323 | 0 | 2 | 18 | |
| TCGA | HAUS8 | 93323 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of HAUS8:
Generating mutation plots.
Highly correlated genes for HAUS8:
Showing top 20/773 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAUS8 | NCAPH | 0.809408 | 5 | 0 | 5 |
| HAUS8 | CDC6 | 0.790631 | 6 | 0 | 6 |
| HAUS8 | BUB1B | 0.789902 | 6 | 0 | 6 |
| HAUS8 | NR2E1 | 0.782785 | 3 | 0 | 3 |
| HAUS8 | RAD51 | 0.78001 | 8 | 0 | 8 |
| HAUS8 | PNPT1 | 0.769532 | 5 | 0 | 5 |
| HAUS8 | FAM24B | 0.768476 | 3 | 0 | 3 |
| HAUS8 | UBE2T | 0.767432 | 7 | 0 | 7 |
| HAUS8 | TNFAIP8L1 | 0.765556 | 6 | 0 | 6 |
| HAUS8 | CENPN | 0.761941 | 7 | 0 | 7 |
| HAUS8 | COLGALT1 | 0.761839 | 6 | 0 | 6 |
| HAUS8 | UBE2S | 0.758224 | 6 | 0 | 6 |
| HAUS8 | KNSTRN | 0.75773 | 7 | 0 | 7 |
| HAUS8 | CKS1B | 0.756954 | 7 | 0 | 6 |
| HAUS8 | PSMB3 | 0.756041 | 6 | 0 | 6 |
| HAUS8 | RFC4 | 0.755072 | 7 | 0 | 6 |
| HAUS8 | CBX3 | 0.750751 | 7 | 0 | 7 |
| HAUS8 | CEP55 | 0.750056 | 7 | 0 | 7 |
| HAUS8 | MTFR2 | 0.747224 | 7 | 0 | 7 |
| HAUS8 | LRWD1 | 0.74648 | 3 | 0 | 3 |
For details and further investigation, click here
