| Full name: taste 2 receptor member 14 | Alias Symbol: T2R14|TRB1 | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 50840 | HGNC ID: HGNC:14920 | Ensembl Gene: ENSG00000212127 | OMIM ID: 604790 |
| Drug and gene relationship at DGIdb | |||
Expression of TAS2R14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAS2R14 | 50840 | 235762_at | 0.0932 | 0.8321 | |
| GSE20347 | TAS2R14 | 50840 | 221391_at | -0.0161 | 0.8781 | |
| GSE23400 | TAS2R14 | 50840 | 221391_at | -0.1765 | 0.0000 | |
| GSE26886 | TAS2R14 | 50840 | 235762_at | 1.2602 | 0.0031 | |
| GSE29001 | TAS2R14 | 50840 | 221391_at | -0.3083 | 0.0334 | |
| GSE38129 | TAS2R14 | 50840 | 221391_at | -0.0754 | 0.2878 | |
| GSE45670 | TAS2R14 | 50840 | 235762_at | 0.4630 | 0.2174 | |
| GSE53622 | TAS2R14 | 50840 | 67226 | -1.0316 | 0.0000 | |
| GSE53624 | TAS2R14 | 50840 | 67226 | -1.2571 | 0.0000 | |
| GSE63941 | TAS2R14 | 50840 | 235762_at | -0.8490 | 0.3111 | |
| GSE77861 | TAS2R14 | 50840 | 235762_at | 0.6267 | 0.0829 | |
| GSE97050 | TAS2R14 | 50840 | A_23_P105495 | -0.2710 | 0.3977 | |
| SRP133303 | TAS2R14 | 50840 | RNAseq | 0.3753 | 0.1419 | |
| SRP219564 | TAS2R14 | 50840 | RNAseq | -0.0070 | 0.9889 | |
| TCGA | TAS2R14 | 50840 | RNAseq | -0.3164 | 0.2875 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by TAS2R14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAS2R14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAS2R14 | 50840 | 6 | 2 | 22 | |
| GSE20123 | TAS2R14 | 50840 | 6 | 2 | 22 | |
| GSE43470 | TAS2R14 | 50840 | 9 | 3 | 31 | |
| GSE46452 | TAS2R14 | 50840 | 10 | 1 | 48 | |
| GSE47630 | TAS2R14 | 50840 | 14 | 2 | 24 | |
| GSE54993 | TAS2R14 | 50840 | 1 | 10 | 59 | |
| GSE54994 | TAS2R14 | 50840 | 9 | 2 | 42 | |
| GSE60625 | TAS2R14 | 50840 | 0 | 1 | 10 | |
| GSE74703 | TAS2R14 | 50840 | 9 | 2 | 25 | |
| GSE74704 | TAS2R14 | 50840 | 4 | 1 | 15 | |
| TCGA | TAS2R14 | 50840 | 38 | 8 | 50 |
Total number of gains: 106; Total number of losses: 34; Total Number of normals: 348.
Somatic mutations of TAS2R14:
Generating mutation plots.
Highly correlated genes for TAS2R14:
Showing top 20/198 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAS2R14 | C16orf89 | 0.763674 | 3 | 0 | 3 |
| TAS2R14 | OR2Z1 | 0.753676 | 3 | 0 | 3 |
| TAS2R14 | FAM163B | 0.741222 | 3 | 0 | 3 |
| TAS2R14 | BARHL2 | 0.735023 | 3 | 0 | 3 |
| TAS2R14 | RNF222 | 0.734689 | 3 | 0 | 3 |
| TAS2R14 | KPRP | 0.726534 | 3 | 0 | 3 |
| TAS2R14 | DCD | 0.719902 | 3 | 0 | 3 |
| TAS2R14 | RRP1 | 0.718774 | 3 | 0 | 3 |
| TAS2R14 | NOTO | 0.717177 | 3 | 0 | 3 |
| TAS2R14 | KRTAP20-1 | 0.712922 | 3 | 0 | 3 |
| TAS2R14 | OR10G3 | 0.70838 | 3 | 0 | 3 |
| TAS2R14 | PCSK1N | 0.697672 | 3 | 0 | 3 |
| TAS2R14 | SERGEF | 0.681222 | 3 | 0 | 3 |
| TAS2R14 | OR5AS1 | 0.675899 | 3 | 0 | 3 |
| TAS2R14 | SLC5A7 | 0.662508 | 5 | 0 | 5 |
| TAS2R14 | OVGP1 | 0.66093 | 4 | 0 | 4 |
| TAS2R14 | PTPRR | 0.657895 | 3 | 0 | 3 |
| TAS2R14 | TTC32 | 0.656224 | 3 | 0 | 3 |
| TAS2R14 | KRTAP5-4 | 0.654629 | 3 | 0 | 3 |
| TAS2R14 | RUFY4 | 0.649583 | 3 | 0 | 3 |
For details and further investigation, click here
