| Full name: mitotic spindle positioning | Alias Symbol: DKFZp686H18209|Caprice|MISP1 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126353 | HGNC ID: HGNC:27000 | Ensembl Gene: ENSG00000099812 | OMIM ID: 615289 |
Expression of MISP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MISP | 126353 | 212925_at | 0.8016 | 0.0803 | |
| GSE20347 | MISP | 126353 | 212925_at | 0.5109 | 0.0000 | |
| GSE23400 | MISP | 126353 | 212925_at | 0.0739 | 0.2207 | |
| GSE26886 | MISP | 126353 | 212925_at | 0.9453 | 0.0000 | |
| GSE29001 | MISP | 126353 | 212925_at | 0.3048 | 0.1725 | |
| GSE38129 | MISP | 126353 | 212925_at | 0.5262 | 0.0013 | |
| GSE45670 | MISP | 126353 | 212925_at | 0.5852 | 0.0008 | |
| GSE53622 | MISP | 126353 | 73483 | 2.5778 | 0.0000 | |
| GSE53624 | MISP | 126353 | 73483 | 2.8443 | 0.0000 | |
| GSE63941 | MISP | 126353 | 212925_at | 1.5027 | 0.0053 | |
| GSE77861 | MISP | 126353 | 212925_at | 0.3113 | 0.1223 | |
| SRP007169 | MISP | 126353 | RNAseq | 2.7632 | 0.0022 | |
| SRP133303 | MISP | 126353 | RNAseq | 3.1989 | 0.0000 | |
| SRP159526 | MISP | 126353 | RNAseq | 3.5267 | 0.0000 | |
| SRP193095 | MISP | 126353 | RNAseq | 1.1728 | 0.0707 | |
| SRP219564 | MISP | 126353 | RNAseq | 5.8674 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by MISP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MISP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MISP | 126353 | 4 | 6 | 20 | |
| GSE20123 | MISP | 126353 | 4 | 5 | 21 | |
| GSE43470 | MISP | 126353 | 1 | 10 | 32 | |
| GSE46452 | MISP | 126353 | 47 | 1 | 11 | |
| GSE47630 | MISP | 126353 | 5 | 7 | 28 | |
| GSE54993 | MISP | 126353 | 13 | 4 | 53 | |
| GSE54994 | MISP | 126353 | 8 | 15 | 30 | |
| GSE60625 | MISP | 126353 | 9 | 0 | 2 | |
| GSE74703 | MISP | 126353 | 1 | 7 | 28 | |
| GSE74704 | MISP | 126353 | 3 | 3 | 14 | |
| TCGA | MISP | 126353 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 83; Total Number of normals: 302.
Somatic mutations of MISP:
Generating mutation plots.
Highly correlated genes for MISP:
Showing top 20/1121 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MISP | DTX3 | 0.780898 | 3 | 0 | 3 |
| MISP | SIX4 | 0.750753 | 5 | 0 | 5 |
| MISP | PRR12 | 0.73798 | 3 | 0 | 3 |
| MISP | SCYL1 | 0.731484 | 3 | 0 | 3 |
| MISP | TMEM223 | 0.726941 | 3 | 0 | 3 |
| MISP | LRP5 | 0.72068 | 4 | 0 | 4 |
| MISP | TTC32 | 0.706053 | 3 | 0 | 3 |
| MISP | FAM161A | 0.703853 | 4 | 0 | 3 |
| MISP | PRR15 | 0.701501 | 4 | 0 | 3 |
| MISP | TNFAIP8L1 | 0.699447 | 4 | 0 | 3 |
| MISP | TMEM184B | 0.687007 | 8 | 0 | 8 |
| MISP | ZNF593 | 0.686014 | 4 | 0 | 4 |
| MISP | CDCA2 | 0.684792 | 4 | 0 | 4 |
| MISP | NOSIP | 0.680799 | 3 | 0 | 3 |
| MISP | CD276 | 0.68076 | 4 | 0 | 4 |
| MISP | LAMA5 | 0.676754 | 8 | 0 | 6 |
| MISP | CDC42EP2 | 0.675585 | 3 | 0 | 3 |
| MISP | CAPN12 | 0.674594 | 3 | 0 | 3 |
| MISP | CITED1 | 0.671789 | 4 | 0 | 3 |
| MISP | CMSS1 | 0.667051 | 5 | 0 | 4 |
For details and further investigation, click here
