PRMT3

 

Full name: protein arginine methyltransferase 3 Alias Symbol: 
Type: protein-coding gene Cytoband: 11p15.1
Entrez ID: 10196 HGNC ID: HGNC:30163 Ensembl Gene: ENSG00000185238 OMIM ID: 603190
Drug and gene relationship at DGIdb

 

Expression of PRMT3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRMT3 10196 213320_at 0.4295 0.4724
GSE20347 PRMT3 10196 213320_at 0.4003 0.1240
GSE23400 PRMT3 10196 213320_at 0.5282 0.0000
GSE26886 PRMT3 10196 213320_at 0.9757 0.0000
GSE29001 PRMT3 10196 213320_at 0.6729 0.0881
GSE38129 PRMT3 10196 213320_at 0.6380 0.0003
GSE45670 PRMT3 10196 213320_at 0.4727 0.0262
GSE53622 PRMT3 10196 121109 0.5073 0.0000
GSE53624 PRMT3 10196 121109 0.4341 0.0000
GSE63941 PRMT3 10196 213320_at 0.5061 0.4238
GSE77861 PRMT3 10196 213320_at 0.8417 0.1945
GSE97050 PRMT3 10196 A_23_P9894 0.2870 0.4110
SRP007169 PRMT3 10196 RNAseq 1.2858 0.0020
SRP008496 PRMT3 10196 RNAseq 1.3183 0.0000
SRP064894 PRMT3 10196 RNAseq 0.2595 0.3481
SRP133303 PRMT3 10196 RNAseq 0.9892 0.0000
SRP159526 PRMT3 10196 RNAseq 0.0245 0.9478
SRP193095 PRMT3 10196 RNAseq 0.1153 0.2861
SRP219564 PRMT3 10196 RNAseq 0.6989 0.1172
TCGA PRMT3 10196 RNAseq 0.2659 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by PRMT3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PRMT3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRMT3 10196 0 9 21
GSE20123 PRMT3 10196 0 10 20
GSE43470 PRMT3 10196 1 5 37
GSE46452 PRMT3 10196 7 5 47
GSE47630 PRMT3 10196 3 10 27
GSE54993 PRMT3 10196 3 0 67
GSE54994 PRMT3 10196 3 12 38
GSE60625 PRMT3 10196 0 0 11
GSE74703 PRMT3 10196 1 3 32
GSE74704 PRMT3 10196 0 8 12
TCGA PRMT3 10196 13 26 57

Total number of gains: 31; Total number of losses: 88; Total Number of normals: 369.  

 

Somatic mutations of PRMT3:

 

Generating mutation plots.

 

Highly correlated genes for PRMT3:

 

Showing top 20/317 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRMT3ZNF6970.751646303
PRMT3ARHGAP210.741861303
PRMT3APBA20.735427303
PRMT3TTC320.728674303
PRMT3C14orf1190.716791303
PRMT3RFT10.688149403
PRMT3KAT2A0.679221403
PRMT3DNLZ0.67614303
PRMT3LRR10.67591707
PRMT3NUP1600.67388311010
PRMT3ERI10.66303403
PRMT3BOP10.662893303
PRMT3C19orf530.660543403
PRMT3ZNF5590.658635403
PRMT3NUP370.64238812010
PRMT3NPW0.641593403
PRMT3PRDM130.641085403
PRMT3CCL260.634095403
PRMT3CDCA50.629844706
PRMT3POC1A0.627524503

For details and further investigation, click here