| Full name: tetratricopeptide repeat domain 39A | Alias Symbol: KIAA0452|DEME-6 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 22996 | HGNC ID: HGNC:18657 | Ensembl Gene: ENSG00000085831 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC39A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC39A | 22996 | 210652_s_at | -0.6168 | 0.6929 | |
| GSE20347 | TTC39A | 22996 | 210652_s_at | -2.2936 | 0.0000 | |
| GSE23400 | TTC39A | 22996 | 215562_at | -0.1632 | 0.0000 | |
| GSE26886 | TTC39A | 22996 | 210652_s_at | -1.5685 | 0.0000 | |
| GSE29001 | TTC39A | 22996 | 210652_s_at | -1.7015 | 0.0002 | |
| GSE38129 | TTC39A | 22996 | 210652_s_at | -1.5244 | 0.0000 | |
| GSE45670 | TTC39A | 22996 | 210652_s_at | -0.5972 | 0.0460 | |
| GSE53622 | TTC39A | 22996 | 100111 | -1.8450 | 0.0000 | |
| GSE53624 | TTC39A | 22996 | 100111 | -2.1991 | 0.0000 | |
| GSE63941 | TTC39A | 22996 | 210652_s_at | 1.7576 | 0.0252 | |
| GSE77861 | TTC39A | 22996 | 210652_s_at | -1.4998 | 0.0007 | |
| GSE97050 | TTC39A | 22996 | A_24_P299210 | -0.0536 | 0.8232 | |
| SRP007169 | TTC39A | 22996 | RNAseq | -3.6731 | 0.0000 | |
| SRP008496 | TTC39A | 22996 | RNAseq | -3.3361 | 0.0000 | |
| SRP064894 | TTC39A | 22996 | RNAseq | -2.0263 | 0.0000 | |
| SRP133303 | TTC39A | 22996 | RNAseq | -1.7795 | 0.0000 | |
| SRP159526 | TTC39A | 22996 | RNAseq | -2.2268 | 0.0000 | |
| SRP193095 | TTC39A | 22996 | RNAseq | -1.8863 | 0.0000 | |
| SRP219564 | TTC39A | 22996 | RNAseq | -2.0925 | 0.0236 | |
| TCGA | TTC39A | 22996 | RNAseq | -0.6856 | 0.0006 |
Upregulated datasets: 1; Downregulated datasets: 14.
Survival by TTC39A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC39A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC39A | 22996 | 3 | 4 | 23 | |
| GSE20123 | TTC39A | 22996 | 3 | 3 | 24 | |
| GSE43470 | TTC39A | 22996 | 5 | 4 | 34 | |
| GSE46452 | TTC39A | 22996 | 2 | 1 | 56 | |
| GSE47630 | TTC39A | 22996 | 8 | 4 | 28 | |
| GSE54993 | TTC39A | 22996 | 0 | 1 | 69 | |
| GSE54994 | TTC39A | 22996 | 11 | 2 | 40 | |
| GSE60625 | TTC39A | 22996 | 0 | 0 | 11 | |
| GSE74703 | TTC39A | 22996 | 4 | 2 | 30 | |
| GSE74704 | TTC39A | 22996 | 2 | 0 | 18 | |
| TCGA | TTC39A | 22996 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 39; Total Number of normals: 401.
Somatic mutations of TTC39A:
Generating mutation plots.
Highly correlated genes for TTC39A:
Showing top 20/760 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC39A | SNORA68 | 0.846357 | 3 | 0 | 3 |
| TTC39A | GRHL1 | 0.793708 | 7 | 0 | 7 |
| TTC39A | DENND2D | 0.792904 | 9 | 0 | 9 |
| TTC39A | C15orf48 | 0.790855 | 6 | 0 | 6 |
| TTC39A | CYSRT1 | 0.790546 | 6 | 0 | 6 |
| TTC39A | GRHL3 | 0.788671 | 6 | 0 | 6 |
| TTC39A | RASAL1 | 0.787784 | 10 | 0 | 10 |
| TTC39A | MAL2 | 0.768674 | 7 | 0 | 7 |
| TTC39A | KRT78 | 0.767696 | 6 | 0 | 6 |
| TTC39A | FAM3D | 0.767255 | 6 | 0 | 6 |
| TTC39A | GP9 | 0.763309 | 3 | 0 | 3 |
| TTC39A | GPT2 | 0.763219 | 7 | 0 | 7 |
| TTC39A | ATP13A4 | 0.760065 | 6 | 0 | 6 |
| TTC39A | TMEM79 | 0.759948 | 7 | 0 | 7 |
| TTC39A | CLIC3 | 0.759615 | 8 | 0 | 7 |
| TTC39A | BTBD19 | 0.758375 | 3 | 0 | 3 |
| TTC39A | FAM171A2 | 0.757996 | 3 | 0 | 3 |
| TTC39A | ZNRF1 | 0.757297 | 4 | 0 | 4 |
| TTC39A | BSPRY | 0.756832 | 11 | 0 | 10 |
| TTC39A | FAM214A | 0.756571 | 5 | 0 | 5 |
For details and further investigation, click here
