| Full name: family with sequence similarity 3 member D | Alias Symbol: EF7|OIT1 | ||
| Type: protein-coding gene | Cytoband: 3p14.2 | ||
| Entrez ID: 131177 | HGNC ID: HGNC:18665 | Ensembl Gene: ENSG00000198643 | OMIM ID: 608619 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM3D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM3D | 131177 | 227676_at | -2.6717 | 0.0399 | |
| GSE26886 | FAM3D | 131177 | 227676_at | -4.1570 | 0.0000 | |
| GSE45670 | FAM3D | 131177 | 227676_at | -1.9049 | 0.0054 | |
| GSE53622 | FAM3D | 131177 | 48864 | -3.9937 | 0.0000 | |
| GSE53624 | FAM3D | 131177 | 48864 | -4.7700 | 0.0000 | |
| GSE63941 | FAM3D | 131177 | 227676_at | 0.3132 | 0.2880 | |
| GSE77861 | FAM3D | 131177 | 227676_at | -2.5338 | 0.0003 | |
| GSE97050 | FAM3D | 131177 | A_23_P41145 | -0.8599 | 0.1726 | |
| SRP007169 | FAM3D | 131177 | RNAseq | -6.3306 | 0.0000 | |
| SRP008496 | FAM3D | 131177 | RNAseq | -5.8374 | 0.0000 | |
| SRP064894 | FAM3D | 131177 | RNAseq | -5.0704 | 0.0000 | |
| SRP133303 | FAM3D | 131177 | RNAseq | -4.2455 | 0.0000 | |
| SRP159526 | FAM3D | 131177 | RNAseq | -4.2749 | 0.0000 | |
| SRP193095 | FAM3D | 131177 | RNAseq | -3.4846 | 0.0000 | |
| SRP219564 | FAM3D | 131177 | RNAseq | -4.6583 | 0.0004 | |
| TCGA | FAM3D | 131177 | RNAseq | -1.4160 | 0.0131 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by FAM3D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM3D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM3D | 131177 | 0 | 17 | 13 | |
| GSE20123 | FAM3D | 131177 | 0 | 18 | 12 | |
| GSE43470 | FAM3D | 131177 | 0 | 17 | 26 | |
| GSE46452 | FAM3D | 131177 | 2 | 17 | 40 | |
| GSE47630 | FAM3D | 131177 | 1 | 24 | 15 | |
| GSE54993 | FAM3D | 131177 | 6 | 2 | 62 | |
| GSE54994 | FAM3D | 131177 | 0 | 32 | 21 | |
| GSE60625 | FAM3D | 131177 | 5 | 0 | 6 | |
| GSE74703 | FAM3D | 131177 | 0 | 14 | 22 | |
| GSE74704 | FAM3D | 131177 | 0 | 11 | 9 | |
| TCGA | FAM3D | 131177 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of FAM3D:
Generating mutation plots.
Highly correlated genes for FAM3D:
Showing top 20/1750 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM3D | SMIM5 | 0.904739 | 6 | 0 | 6 |
| FAM3D | C5orf66-AS1 | 0.904054 | 6 | 0 | 6 |
| FAM3D | CRISP3 | 0.902181 | 7 | 0 | 7 |
| FAM3D | PADI1 | 0.900093 | 4 | 0 | 4 |
| FAM3D | ATP13A4 | 0.881993 | 8 | 0 | 8 |
| FAM3D | KRT78 | 0.881239 | 8 | 0 | 8 |
| FAM3D | LMO7 | 0.878337 | 7 | 0 | 7 |
| FAM3D | KLB | 0.878206 | 6 | 0 | 6 |
| FAM3D | SLC13A4 | 0.871605 | 6 | 0 | 6 |
| FAM3D | GYS2 | 0.87135 | 6 | 0 | 6 |
| FAM3D | SNORA68 | 0.870486 | 4 | 0 | 4 |
| FAM3D | ACPP | 0.867314 | 8 | 0 | 8 |
| FAM3D | UPK1A | 0.866927 | 7 | 0 | 7 |
| FAM3D | TMPRSS11B | 0.864938 | 8 | 0 | 8 |
| FAM3D | VSIG10L | 0.862373 | 7 | 0 | 7 |
| FAM3D | SCNN1B | 0.861099 | 8 | 0 | 8 |
| FAM3D | SLC35C1 | 0.858307 | 6 | 0 | 6 |
| FAM3D | MAPK3 | 0.858305 | 7 | 0 | 7 |
| FAM3D | AGFG2 | 0.854332 | 7 | 0 | 7 |
| FAM3D | SLC16A6 | 0.850812 | 7 | 0 | 7 |
For details and further investigation, click here
