| Full name: chromosome 15 open reading frame 48 | Alias Symbol: NMES1|MIR147BHG | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 84419 | HGNC ID: HGNC:29898 | Ensembl Gene: ENSG00000166920 | OMIM ID: 608409 |
| Drug and gene relationship at DGIdb | |||
Expression of C15orf48:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C15orf48 | 84419 | 223484_at | -1.5037 | 0.4702 | |
| GSE26886 | C15orf48 | 84419 | 223484_at | -5.8902 | 0.0000 | |
| GSE45670 | C15orf48 | 84419 | 223484_at | -0.4362 | 0.4253 | |
| GSE53622 | C15orf48 | 84419 | 57008 | -2.3798 | 0.0000 | |
| GSE53624 | C15orf48 | 84419 | 57008 | -3.2056 | 0.0000 | |
| GSE63941 | C15orf48 | 84419 | 223484_at | 1.5357 | 0.4595 | |
| GSE77861 | C15orf48 | 84419 | 223484_at | -2.3954 | 0.0011 | |
| GSE97050 | C15orf48 | 84419 | A_23_P26024 | -0.2608 | 0.7764 | |
| SRP007169 | C15orf48 | 84419 | RNAseq | -4.9208 | 0.0000 | |
| SRP008496 | C15orf48 | 84419 | RNAseq | -5.2804 | 0.0000 | |
| SRP064894 | C15orf48 | 84419 | RNAseq | -3.4430 | 0.0000 | |
| SRP133303 | C15orf48 | 84419 | RNAseq | -2.1103 | 0.0000 | |
| SRP159526 | C15orf48 | 84419 | RNAseq | -3.8079 | 0.0000 | |
| SRP193095 | C15orf48 | 84419 | RNAseq | -3.0501 | 0.0000 | |
| SRP219564 | C15orf48 | 84419 | RNAseq | -3.8987 | 0.0007 | |
| TCGA | C15orf48 | 84419 | RNAseq | -0.1728 | 0.3973 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by C15orf48 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C15orf48:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C15orf48 | 84419 | 4 | 5 | 21 | |
| GSE20123 | C15orf48 | 84419 | 4 | 5 | 21 | |
| GSE43470 | C15orf48 | 84419 | 4 | 4 | 35 | |
| GSE46452 | C15orf48 | 84419 | 3 | 7 | 49 | |
| GSE47630 | C15orf48 | 84419 | 8 | 10 | 22 | |
| GSE54993 | C15orf48 | 84419 | 4 | 5 | 61 | |
| GSE54994 | C15orf48 | 84419 | 5 | 7 | 41 | |
| GSE60625 | C15orf48 | 84419 | 4 | 0 | 7 | |
| GSE74703 | C15orf48 | 84419 | 4 | 3 | 29 | |
| GSE74704 | C15orf48 | 84419 | 2 | 3 | 15 | |
| TCGA | C15orf48 | 84419 | 11 | 16 | 69 |
Total number of gains: 53; Total number of losses: 65; Total Number of normals: 370.
Somatic mutations of C15orf48:
Generating mutation plots.
Highly correlated genes for C15orf48:
Showing top 20/1420 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C15orf48 | KRT83 | 0.847896 | 3 | 0 | 3 |
| C15orf48 | TMOD3 | 0.843661 | 7 | 0 | 7 |
| C15orf48 | TMPRSS11E | 0.838338 | 7 | 0 | 7 |
| C15orf48 | TMEM154 | 0.838058 | 7 | 0 | 7 |
| C15orf48 | CYSRT1 | 0.833516 | 6 | 0 | 6 |
| C15orf48 | UPK3B | 0.827853 | 3 | 0 | 3 |
| C15orf48 | ESPL1 | 0.822936 | 7 | 0 | 7 |
| C15orf48 | TTC22 | 0.815873 | 7 | 0 | 7 |
| C15orf48 | FUT3 | 0.815692 | 8 | 0 | 8 |
| C15orf48 | CAPN14 | 0.813337 | 7 | 0 | 7 |
| C15orf48 | CAPN5 | 0.812324 | 6 | 0 | 6 |
| C15orf48 | RAB11A | 0.811515 | 6 | 0 | 6 |
| C15orf48 | PADI1 | 0.810593 | 4 | 0 | 4 |
| C15orf48 | FLG | 0.810233 | 7 | 0 | 7 |
| C15orf48 | FCHO2 | 0.80912 | 6 | 0 | 6 |
| C15orf48 | FAM214A | 0.804786 | 6 | 0 | 6 |
| C15orf48 | SH3PXD2A-AS1 | 0.804438 | 4 | 0 | 4 |
| C15orf48 | RAET1E | 0.80427 | 7 | 0 | 7 |
| C15orf48 | TMPRSS11B | 0.804168 | 8 | 0 | 8 |
| C15orf48 | NCCRP1 | 0.803057 | 4 | 0 | 4 |
For details and further investigation, click here
