| Full name: chloride intracellular channel 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 9022 | HGNC ID: HGNC:2064 | Ensembl Gene: ENSG00000169583 | OMIM ID: 606533 |
| Drug and gene relationship at DGIdb | |||
Expression of CLIC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLIC3 | 9022 | 219529_at | -2.9025 | 0.0942 | |
| GSE20347 | CLIC3 | 9022 | 219529_at | -5.1724 | 0.0000 | |
| GSE23400 | CLIC3 | 9022 | 219529_at | -3.6849 | 0.0000 | |
| GSE26886 | CLIC3 | 9022 | 219529_at | -4.5783 | 0.0000 | |
| GSE29001 | CLIC3 | 9022 | 219529_at | -4.4041 | 0.0000 | |
| GSE38129 | CLIC3 | 9022 | 219529_at | -3.6824 | 0.0000 | |
| GSE45670 | CLIC3 | 9022 | 219529_at | -1.3852 | 0.0183 | |
| GSE63941 | CLIC3 | 9022 | 219529_at | 0.5702 | 0.7595 | |
| GSE77861 | CLIC3 | 9022 | 219529_at | -3.3339 | 0.0044 | |
| GSE97050 | CLIC3 | 9022 | A_33_P3336686 | -0.6369 | 0.3082 | |
| SRP007169 | CLIC3 | 9022 | RNAseq | -5.7934 | 0.0000 | |
| SRP008496 | CLIC3 | 9022 | RNAseq | -5.2796 | 0.0000 | |
| SRP064894 | CLIC3 | 9022 | RNAseq | -3.5890 | 0.0000 | |
| SRP133303 | CLIC3 | 9022 | RNAseq | -4.6633 | 0.0000 | |
| SRP159526 | CLIC3 | 9022 | RNAseq | -5.1223 | 0.0000 | |
| SRP193095 | CLIC3 | 9022 | RNAseq | -4.3377 | 0.0000 | |
| SRP219564 | CLIC3 | 9022 | RNAseq | -3.9877 | 0.0001 | |
| TCGA | CLIC3 | 9022 | RNAseq | 0.0493 | 0.8576 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by CLIC3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CLIC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLIC3 | 9022 | 5 | 7 | 18 | |
| GSE20123 | CLIC3 | 9022 | 5 | 7 | 18 | |
| GSE43470 | CLIC3 | 9022 | 3 | 7 | 33 | |
| GSE46452 | CLIC3 | 9022 | 6 | 13 | 40 | |
| GSE47630 | CLIC3 | 9022 | 6 | 15 | 19 | |
| GSE54993 | CLIC3 | 9022 | 3 | 3 | 64 | |
| GSE54994 | CLIC3 | 9022 | 12 | 8 | 33 | |
| GSE60625 | CLIC3 | 9022 | 0 | 0 | 11 | |
| GSE74703 | CLIC3 | 9022 | 3 | 5 | 28 | |
| GSE74704 | CLIC3 | 9022 | 3 | 5 | 12 | |
| TCGA | CLIC3 | 9022 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of CLIC3:
Generating mutation plots.
Highly correlated genes for CLIC3:
Showing top 20/1722 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLIC3 | CYSRT1 | 0.956895 | 4 | 0 | 4 |
| CLIC3 | ENDOU | 0.916924 | 9 | 0 | 9 |
| CLIC3 | KALRN | 0.904899 | 4 | 0 | 4 |
| CLIC3 | CRISP3 | 0.904743 | 9 | 0 | 9 |
| CLIC3 | TGM1 | 0.904107 | 10 | 0 | 10 |
| CLIC3 | SPINK5 | 0.900561 | 10 | 0 | 10 |
| CLIC3 | SCEL | 0.898406 | 10 | 0 | 10 |
| CLIC3 | SLURP1 | 0.897757 | 10 | 0 | 10 |
| CLIC3 | FUT6 | 0.895827 | 8 | 0 | 8 |
| CLIC3 | CWH43 | 0.893888 | 8 | 0 | 8 |
| CLIC3 | CNFN | 0.892735 | 6 | 0 | 6 |
| CLIC3 | PPL | 0.891488 | 10 | 0 | 10 |
| CLIC3 | TMPRSS11E | 0.891165 | 9 | 0 | 9 |
| CLIC3 | ECM1 | 0.883986 | 10 | 0 | 10 |
| CLIC3 | A2ML1 | 0.88255 | 6 | 0 | 6 |
| CLIC3 | TTC9 | 0.882481 | 9 | 0 | 9 |
| CLIC3 | GDPD3 | 0.881852 | 10 | 0 | 10 |
| CLIC3 | EVPL | 0.881368 | 10 | 0 | 10 |
| CLIC3 | VSIG10L | 0.88052 | 5 | 0 | 5 |
| CLIC3 | CSTB | 0.880038 | 10 | 0 | 10 |
For details and further investigation, click here
