| Full name: mal, T cell differentiation protein 2 (gene/pseudogene) | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.12 | ||
| Entrez ID: 114569 | HGNC ID: HGNC:13634 | Ensembl Gene: ENSG00000147676 | OMIM ID: 609684 |
| Drug and gene relationship at DGIdb | |||
Expression of MAL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAL2 | 114569 | 224650_at | 0.0774 | 0.9613 | |
| GSE26886 | MAL2 | 114569 | 224650_at | -2.0345 | 0.0000 | |
| GSE45670 | MAL2 | 114569 | 224650_at | -0.3358 | 0.0364 | |
| GSE53622 | MAL2 | 114569 | 37020 | -0.7710 | 0.0041 | |
| GSE53624 | MAL2 | 114569 | 37020 | -1.5697 | 0.0000 | |
| GSE63941 | MAL2 | 114569 | 224650_at | 7.8788 | 0.0000 | |
| GSE77861 | MAL2 | 114569 | 224650_at | -1.0953 | 0.0034 | |
| GSE97050 | MAL2 | 114569 | A_23_P60130 | 0.5332 | 0.5900 | |
| SRP007169 | MAL2 | 114569 | RNAseq | -1.9661 | 0.0000 | |
| SRP008496 | MAL2 | 114569 | RNAseq | -1.9995 | 0.0000 | |
| SRP064894 | MAL2 | 114569 | RNAseq | -1.4281 | 0.0011 | |
| SRP133303 | MAL2 | 114569 | RNAseq | -1.2596 | 0.0002 | |
| SRP159526 | MAL2 | 114569 | RNAseq | -2.1933 | 0.0000 | |
| SRP193095 | MAL2 | 114569 | RNAseq | -1.8186 | 0.0000 | |
| SRP219564 | MAL2 | 114569 | RNAseq | -2.0633 | 0.1043 | |
| TCGA | MAL2 | 114569 | RNAseq | 0.1330 | 0.2949 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by MAL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAL2 | 114569 | 19 | 1 | 10 | |
| GSE20123 | MAL2 | 114569 | 20 | 1 | 9 | |
| GSE43470 | MAL2 | 114569 | 23 | 0 | 20 | |
| GSE46452 | MAL2 | 114569 | 26 | 0 | 33 | |
| GSE47630 | MAL2 | 114569 | 24 | 0 | 16 | |
| GSE54993 | MAL2 | 114569 | 0 | 20 | 50 | |
| GSE54994 | MAL2 | 114569 | 37 | 1 | 15 | |
| GSE60625 | MAL2 | 114569 | 0 | 4 | 7 | |
| GSE74703 | MAL2 | 114569 | 19 | 0 | 17 | |
| GSE74704 | MAL2 | 114569 | 13 | 1 | 6 | |
| TCGA | MAL2 | 114569 | 67 | 2 | 27 |
Total number of gains: 248; Total number of losses: 30; Total Number of normals: 210.
Somatic mutations of MAL2:
Generating mutation plots.
Highly correlated genes for MAL2:
Showing top 20/1129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAL2 | GPD1L | 0.812902 | 4 | 0 | 4 |
| MAL2 | CDS1 | 0.809482 | 8 | 0 | 8 |
| MAL2 | C15orf48 | 0.790636 | 7 | 0 | 7 |
| MAL2 | EPHA1 | 0.785962 | 8 | 0 | 8 |
| MAL2 | SPAG17 | 0.782463 | 4 | 0 | 4 |
| MAL2 | OCLN | 0.780475 | 8 | 0 | 8 |
| MAL2 | TTC22 | 0.779892 | 8 | 0 | 8 |
| MAL2 | RBM47 | 0.776633 | 9 | 0 | 9 |
| MAL2 | VAMP8 | 0.774843 | 8 | 0 | 7 |
| MAL2 | C1orf116 | 0.7744 | 8 | 0 | 8 |
| MAL2 | TTC39A | 0.768674 | 7 | 0 | 7 |
| MAL2 | ARHGAP32 | 0.76494 | 7 | 0 | 7 |
| MAL2 | SPINT2 | 0.763822 | 5 | 0 | 5 |
| MAL2 | TGM1 | 0.763783 | 6 | 0 | 6 |
| MAL2 | PGLYRP3 | 0.763224 | 3 | 0 | 3 |
| MAL2 | RAB25 | 0.763146 | 9 | 0 | 8 |
| MAL2 | DENND2D | 0.762832 | 7 | 0 | 7 |
| MAL2 | MAPK13 | 0.762792 | 8 | 0 | 8 |
| MAL2 | MPZL2 | 0.76098 | 8 | 0 | 8 |
| MAL2 | MACC1 | 0.760072 | 8 | 0 | 8 |
For details and further investigation, click here
