| Full name: zinc and ring finger 1 | Alias Symbol: nin283|FLJ14846|DKFZp434E229 | ||
| Type: protein-coding gene | Cytoband: 16q23.1 | ||
| Entrez ID: 84937 | HGNC ID: HGNC:18452 | Ensembl Gene: ENSG00000186187 | OMIM ID: 612060 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNRF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNRF1 | 84937 | 223382_s_at | -0.3419 | 0.6244 | |
| GSE26886 | ZNRF1 | 84937 | 223382_s_at | -1.4224 | 0.0000 | |
| GSE45670 | ZNRF1 | 84937 | 223382_s_at | -0.6051 | 0.0196 | |
| GSE63941 | ZNRF1 | 84937 | 223382_s_at | -0.2653 | 0.6718 | |
| GSE77861 | ZNRF1 | 84937 | 223382_s_at | -0.8782 | 0.0085 | |
| GSE97050 | ZNRF1 | 84937 | A_24_P16610 | -0.0342 | 0.8933 | |
| SRP007169 | ZNRF1 | 84937 | RNAseq | -3.5962 | 0.0000 | |
| SRP008496 | ZNRF1 | 84937 | RNAseq | -3.2676 | 0.0000 | |
| SRP064894 | ZNRF1 | 84937 | RNAseq | -1.7240 | 0.0000 | |
| SRP133303 | ZNRF1 | 84937 | RNAseq | -0.8921 | 0.0001 | |
| SRP159526 | ZNRF1 | 84937 | RNAseq | -1.0403 | 0.0000 | |
| SRP193095 | ZNRF1 | 84937 | RNAseq | -1.4222 | 0.0000 | |
| SRP219564 | ZNRF1 | 84937 | RNAseq | -1.7432 | 0.0022 | |
| TCGA | ZNRF1 | 84937 | RNAseq | 0.0444 | 0.4634 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by ZNRF1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNRF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNRF1 | 84937 | 6 | 1 | 23 | |
| GSE20123 | ZNRF1 | 84937 | 6 | 1 | 23 | |
| GSE43470 | ZNRF1 | 84937 | 2 | 8 | 33 | |
| GSE46452 | ZNRF1 | 84937 | 37 | 2 | 20 | |
| GSE47630 | ZNRF1 | 84937 | 11 | 8 | 21 | |
| GSE54993 | ZNRF1 | 84937 | 2 | 4 | 64 | |
| GSE54994 | ZNRF1 | 84937 | 8 | 10 | 35 | |
| GSE60625 | ZNRF1 | 84937 | 4 | 0 | 7 | |
| GSE74703 | ZNRF1 | 84937 | 2 | 5 | 29 | |
| GSE74704 | ZNRF1 | 84937 | 3 | 0 | 17 | |
| TCGA | ZNRF1 | 84937 | 25 | 15 | 56 |
Total number of gains: 106; Total number of losses: 54; Total Number of normals: 328.
Somatic mutations of ZNRF1:
Generating mutation plots.
Highly correlated genes for ZNRF1:
Showing top 20/1117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNRF1 | SFTA2 | 0.857964 | 4 | 0 | 4 |
| ZNRF1 | PHACTR4 | 0.842399 | 4 | 0 | 4 |
| ZNRF1 | RNF10 | 0.830315 | 3 | 0 | 3 |
| ZNRF1 | SMIM5 | 0.828985 | 4 | 0 | 4 |
| ZNRF1 | TP53INP2 | 0.828248 | 3 | 0 | 3 |
| ZNRF1 | PSCA | 0.819772 | 4 | 0 | 4 |
| ZNRF1 | TTC9 | 0.819659 | 5 | 0 | 5 |
| ZNRF1 | RBM47 | 0.816861 | 4 | 0 | 4 |
| ZNRF1 | GYS2 | 0.815604 | 4 | 0 | 4 |
| ZNRF1 | ARHGAP27 | 0.814417 | 5 | 0 | 5 |
| ZNRF1 | FUT3 | 0.810951 | 5 | 0 | 5 |
| ZNRF1 | SLC46A2 | 0.809038 | 4 | 0 | 4 |
| ZNRF1 | RMND5B | 0.803141 | 4 | 0 | 4 |
| ZNRF1 | EPS8L1 | 0.80174 | 5 | 0 | 5 |
| ZNRF1 | C5orf66-AS1 | 0.799024 | 4 | 0 | 4 |
| ZNRF1 | ELMO2 | 0.798769 | 4 | 0 | 4 |
| ZNRF1 | ECM1 | 0.797728 | 4 | 0 | 4 |
| ZNRF1 | SORT1 | 0.79433 | 3 | 0 | 3 |
| ZNRF1 | HCG22 | 0.792726 | 4 | 0 | 4 |
| ZNRF1 | KLB | 0.79261 | 4 | 0 | 4 |
For details and further investigation, click here
