RHOBTB1

 

Full name: Rho related BTB domain containing 1 Alias Symbol: KIAA0740
Type: protein-coding gene Cytoband: 10q21.2
Entrez ID: 9886 HGNC ID: HGNC:18738 Ensembl Gene: ENSG00000072422 OMIM ID: 607351
Drug and gene relationship at DGIdb

 

Expression of RHOBTB1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RHOBTB1 9886 212651_at 0.7703 0.2319
GSE20347 RHOBTB1 9886 212651_at 0.9466 0.0000
GSE23400 RHOBTB1 9886 212651_at 0.2997 0.0004
GSE26886 RHOBTB1 9886 212651_at 1.9750 0.0000
GSE29001 RHOBTB1 9886 212651_at 0.8452 0.0107
GSE38129 RHOBTB1 9886 212651_at 0.6488 0.0646
GSE45670 RHOBTB1 9886 212651_at -0.0989 0.8450
GSE53622 RHOBTB1 9886 30936 0.4601 0.0010
GSE53624 RHOBTB1 9886 30936 1.2474 0.0000
GSE63941 RHOBTB1 9886 212651_at -4.3479 0.0015
GSE77861 RHOBTB1 9886 212651_at 0.6061 0.0199
GSE97050 RHOBTB1 9886 A_33_P3348288 -0.3120 0.4259
SRP007169 RHOBTB1 9886 RNAseq 2.4287 0.0003
SRP008496 RHOBTB1 9886 RNAseq 2.6582 0.0000
SRP064894 RHOBTB1 9886 RNAseq 1.2490 0.0000
SRP133303 RHOBTB1 9886 RNAseq 1.1635 0.0001
SRP159526 RHOBTB1 9886 RNAseq 1.1119 0.0068
SRP193095 RHOBTB1 9886 RNAseq 0.1701 0.6982
SRP219564 RHOBTB1 9886 RNAseq 0.5803 0.4518
TCGA RHOBTB1 9886 RNAseq -0.5047 0.0003

Upregulated datasets: 7; Downregulated datasets: 1.  

 

Survival by RHOBTB1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RHOBTB1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RHOBTB1 9886 2 7 21
GSE20123 RHOBTB1 9886 2 7 21
GSE43470 RHOBTB1 9886 2 5 36
GSE46452 RHOBTB1 9886 0 11 48
GSE47630 RHOBTB1 9886 4 12 24
GSE54993 RHOBTB1 9886 9 0 61
GSE54994 RHOBTB1 9886 2 10 41
GSE60625 RHOBTB1 9886 0 0 11
GSE74703 RHOBTB1 9886 2 3 31
GSE74704 RHOBTB1 9886 1 5 14
TCGA RHOBTB1 9886 11 23 62

Total number of gains: 35; Total number of losses: 83; Total Number of normals: 370.  

 

Somatic mutations of RHOBTB1:

 

Generating mutation plots.

 

Highly correlated genes for RHOBTB1:

 

Showing top 20/1443 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RHOBTB1FBN10.80477210010
RHOBTB1TMEM2630.785328707
RHOBTB1TTC7B0.757135707
RHOBTB1C11orf960.754764404
RHOBTB1FSTL10.75319913013
RHOBTB1LAMC10.74956613013
RHOBTB1VCAN0.73901412012
RHOBTB1FAM229B0.737683303
RHOBTB1DACT10.73669813013
RHOBTB1MICAL20.735256909
RHOBTB1GALNT100.73263711011
RHOBTB1COL4A20.73010512012
RHOBTB1LNP10.727485303
RHOBTB1FAP0.72673510010
RHOBTB1ISLR0.72246112012
RHOBTB1ITGB10.72179813013
RHOBTB1RGS30.71743910010
RHOBTB1BICC10.714989908
RHOBTB1DNM1L0.714505303
RHOBTB1POSTN0.71302312011

For details and further investigation, click here