| Full name: caudal type homeobox 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 1044 | HGNC ID: HGNC:1805 | Ensembl Gene: ENSG00000113722 | OMIM ID: 600746 |
| Drug and gene relationship at DGIdb | |||
Expression of CDX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDX1 | 1044 | 206430_at | 0.0864 | 0.6388 | |
| GSE20347 | CDX1 | 1044 | 206430_at | -0.0702 | 0.5293 | |
| GSE23400 | CDX1 | 1044 | 206430_at | -0.0180 | 0.5570 | |
| GSE26886 | CDX1 | 1044 | 206430_at | 0.0844 | 0.6147 | |
| GSE29001 | CDX1 | 1044 | 206430_at | -0.2114 | 0.0702 | |
| GSE38129 | CDX1 | 1044 | 206430_at | -0.1598 | 0.0842 | |
| GSE45670 | CDX1 | 1044 | 206430_at | 0.1624 | 0.0763 | |
| GSE53622 | CDX1 | 1044 | 13587 | -2.2987 | 0.0000 | |
| GSE53624 | CDX1 | 1044 | 13587 | -2.2463 | 0.0000 | |
| GSE63941 | CDX1 | 1044 | 206430_at | 0.4495 | 0.0467 | |
| GSE77861 | CDX1 | 1044 | 206430_at | -0.0435 | 0.8175 | |
| GSE97050 | CDX1 | 1044 | A_33_P3289848 | -1.0748 | 0.1247 | |
| TCGA | CDX1 | 1044 | RNAseq | 2.6218 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by CDX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDX1 | 1044 | 1 | 12 | 17 | |
| GSE20123 | CDX1 | 1044 | 1 | 12 | 17 | |
| GSE43470 | CDX1 | 1044 | 1 | 10 | 32 | |
| GSE46452 | CDX1 | 1044 | 0 | 27 | 32 | |
| GSE47630 | CDX1 | 1044 | 0 | 20 | 20 | |
| GSE54993 | CDX1 | 1044 | 9 | 1 | 60 | |
| GSE54994 | CDX1 | 1044 | 2 | 15 | 36 | |
| GSE60625 | CDX1 | 1044 | 0 | 0 | 11 | |
| GSE74703 | CDX1 | 1044 | 1 | 7 | 28 | |
| GSE74704 | CDX1 | 1044 | 1 | 7 | 12 | |
| TCGA | CDX1 | 1044 | 5 | 38 | 53 |
Total number of gains: 21; Total number of losses: 149; Total Number of normals: 318.
Somatic mutations of CDX1:
Generating mutation plots.
Highly correlated genes for CDX1:
Showing top 20/737 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDX1 | CASC3 | 0.860405 | 3 | 0 | 3 |
| CDX1 | GPD1L | 0.812504 | 3 | 0 | 3 |
| CDX1 | CA13 | 0.796093 | 3 | 0 | 3 |
| CDX1 | SLC10A5 | 0.775909 | 3 | 0 | 3 |
| CDX1 | MYZAP | 0.767935 | 3 | 0 | 3 |
| CDX1 | ACADM | 0.758799 | 3 | 0 | 3 |
| CDX1 | GPX3 | 0.753857 | 4 | 0 | 4 |
| CDX1 | PALMD | 0.751406 | 3 | 0 | 3 |
| CDX1 | BRK1 | 0.748372 | 3 | 0 | 3 |
| CDX1 | ACOT8 | 0.73897 | 3 | 0 | 3 |
| CDX1 | VPS4B | 0.732801 | 4 | 0 | 4 |
| CDX1 | PLXNB1 | 0.716687 | 4 | 0 | 4 |
| CDX1 | ITPKC | 0.708936 | 4 | 0 | 4 |
| CDX1 | TRIM39 | 0.704902 | 3 | 0 | 3 |
| CDX1 | EPGN | 0.704531 | 3 | 0 | 3 |
| CDX1 | CIITA | 0.702884 | 5 | 0 | 5 |
| CDX1 | DENND4C | 0.695252 | 3 | 0 | 3 |
| CDX1 | FSTL4 | 0.692481 | 4 | 0 | 3 |
| CDX1 | CNN3 | 0.691118 | 3 | 0 | 3 |
| CDX1 | ANKRD12 | 0.690491 | 3 | 0 | 3 |
For details and further investigation, click here
