| Full name: tubulin alpha 3c | Alias Symbol: bA408E5.3 | ||
| Type: protein-coding gene | Cytoband: 13q12.11 | ||
| Entrez ID: 7278 | HGNC ID: HGNC:12408 | Ensembl Gene: ENSG00000198033 | OMIM ID: 602528 |
| Drug and gene relationship at DGIdb | |||
TUBA3C involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04210 | Apoptosis | |
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBA3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TUBA3C | 7278 | 4211 | 0.1253 | 0.2891 | |
| GSE53624 | TUBA3C | 7278 | 4211 | 0.1130 | 0.1504 | |
| GSE97050 | TUBA3C | 7278 | A_23_P128598 | 0.3784 | 0.1655 | |
| TCGA | TUBA3C | 7278 | RNAseq | -3.8995 | 0.0031 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TUBA3C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUBA3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBA3C | 7278 | 1 | 15 | 14 | |
| GSE20123 | TUBA3C | 7278 | 1 | 14 | 15 | |
| GSE43470 | TUBA3C | 7278 | 1 | 13 | 29 | |
| GSE46452 | TUBA3C | 7278 | 0 | 33 | 26 | |
| GSE47630 | TUBA3C | 7278 | 3 | 26 | 11 | |
| GSE54993 | TUBA3C | 7278 | 11 | 2 | 57 | |
| GSE54994 | TUBA3C | 7278 | 3 | 12 | 38 | |
| GSE60625 | TUBA3C | 7278 | 0 | 3 | 8 | |
| GSE74703 | TUBA3C | 7278 | 1 | 10 | 25 | |
| GSE74704 | TUBA3C | 7278 | 0 | 12 | 8 | |
| TCGA | TUBA3C | 7278 | 7 | 42 | 47 |
Total number of gains: 28; Total number of losses: 182; Total Number of normals: 278.
Somatic mutations of TUBA3C:
Generating mutation plots.
Highly correlated genes for TUBA3C:
Showing all 13 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBA3C | DUSP9 | 0.746566 | 3 | 0 | 3 |
| TUBA3C | LTB4R2 | 0.701195 | 3 | 0 | 3 |
| TUBA3C | ELMO3 | 0.669534 | 3 | 0 | 3 |
| TUBA3C | KRT16 | 0.658983 | 3 | 0 | 3 |
| TUBA3C | UPP1 | 0.625104 | 3 | 0 | 3 |
| TUBA3C | UCN2 | 0.620661 | 3 | 0 | 3 |
| TUBA3C | MICALL1 | 0.620464 | 3 | 0 | 3 |
| TUBA3C | KRT6C | 0.603849 | 3 | 0 | 3 |
| TUBA3C | KRT6B | 0.593244 | 3 | 0 | 3 |
| TUBA3C | FABP5 | 0.569758 | 3 | 0 | 3 |
| TUBA3C | KRT5 | 0.56357 | 3 | 0 | 3 |
| TUBA3C | KRT6A | 0.555624 | 3 | 0 | 3 |
| TUBA3C | GPR87 | 0.536972 | 3 | 0 | 3 |
For details and further investigation, click here
