| Full name: G protein-coupled receptor 87 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q25.1 | ||
| Entrez ID: 53836 | HGNC ID: HGNC:4538 | Ensembl Gene: ENSG00000138271 | OMIM ID: 606379 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR87:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR87 | 53836 | 219936_s_at | 0.0981 | 0.9278 | |
| GSE20347 | GPR87 | 53836 | 219936_s_at | -0.1776 | 0.3641 | |
| GSE23400 | GPR87 | 53836 | 219936_s_at | 0.3230 | 0.1000 | |
| GSE26886 | GPR87 | 53836 | 219936_s_at | -0.5102 | 0.2084 | |
| GSE29001 | GPR87 | 53836 | 219936_s_at | -0.1781 | 0.6800 | |
| GSE38129 | GPR87 | 53836 | 219936_s_at | 0.7964 | 0.2043 | |
| GSE45670 | GPR87 | 53836 | 219936_s_at | 0.2535 | 0.2127 | |
| GSE53622 | GPR87 | 53836 | 85573 | 0.2360 | 0.3815 | |
| GSE53624 | GPR87 | 53836 | 85573 | -0.3641 | 0.0131 | |
| GSE63941 | GPR87 | 53836 | 219936_s_at | 5.5026 | 0.0002 | |
| GSE77861 | GPR87 | 53836 | 219936_s_at | -0.2702 | 0.4708 | |
| GSE97050 | GPR87 | 53836 | A_23_P121120 | 0.7723 | 0.2307 | |
| SRP007169 | GPR87 | 53836 | RNAseq | -0.5746 | 0.2308 | |
| SRP008496 | GPR87 | 53836 | RNAseq | -0.2235 | 0.4537 | |
| SRP064894 | GPR87 | 53836 | RNAseq | 0.1060 | 0.8218 | |
| SRP133303 | GPR87 | 53836 | RNAseq | 0.3309 | 0.3061 | |
| SRP159526 | GPR87 | 53836 | RNAseq | -0.4482 | 0.5086 | |
| SRP219564 | GPR87 | 53836 | RNAseq | -0.6159 | 0.6135 | |
| TCGA | GPR87 | 53836 | RNAseq | 1.8739 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by GPR87 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR87:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR87 | 53836 | 20 | 0 | 10 | |
| GSE20123 | GPR87 | 53836 | 20 | 0 | 10 | |
| GSE43470 | GPR87 | 53836 | 23 | 0 | 20 | |
| GSE46452 | GPR87 | 53836 | 18 | 2 | 39 | |
| GSE47630 | GPR87 | 53836 | 19 | 3 | 18 | |
| GSE54993 | GPR87 | 53836 | 1 | 10 | 59 | |
| GSE54994 | GPR87 | 53836 | 37 | 1 | 15 | |
| GSE60625 | GPR87 | 53836 | 0 | 6 | 5 | |
| GSE74703 | GPR87 | 53836 | 20 | 0 | 16 | |
| GSE74704 | GPR87 | 53836 | 13 | 0 | 7 | |
| TCGA | GPR87 | 53836 | 72 | 1 | 23 |
Total number of gains: 243; Total number of losses: 23; Total Number of normals: 222.
Somatic mutations of GPR87:
Generating mutation plots.
Highly correlated genes for GPR87:
Showing top 20/405 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR87 | PKP1 | 0.734914 | 8 | 0 | 8 |
| GPR87 | MTFP1 | 0.722146 | 3 | 0 | 3 |
| GPR87 | S100A11 | 0.699644 | 8 | 0 | 6 |
| GPR87 | GJB5 | 0.692036 | 10 | 0 | 8 |
| GPR87 | PLCB3 | 0.690769 | 4 | 0 | 4 |
| GPR87 | SERPINB5 | 0.684095 | 9 | 0 | 8 |
| GPR87 | LAD1 | 0.67621 | 8 | 0 | 5 |
| GPR87 | KRT6A | 0.672196 | 8 | 0 | 5 |
| GPR87 | DSC3 | 0.6658 | 9 | 0 | 7 |
| GPR87 | SLC37A2 | 0.66276 | 5 | 0 | 4 |
| GPR87 | FXYD3 | 0.662363 | 7 | 0 | 6 |
| GPR87 | GINS3 | 0.662044 | 4 | 0 | 4 |
| GPR87 | S100A2 | 0.661717 | 10 | 0 | 7 |
| GPR87 | PTPN3 | 0.656328 | 4 | 0 | 4 |
| GPR87 | AP1S3 | 0.654862 | 5 | 0 | 3 |
| GPR87 | HMGCS1 | 0.653747 | 4 | 0 | 3 |
| GPR87 | DMKN | 0.652746 | 6 | 0 | 5 |
| GPR87 | KRT6C | 0.650641 | 4 | 0 | 3 |
| GPR87 | TRIM29 | 0.648804 | 9 | 0 | 7 |
| GPR87 | IRF6 | 0.648338 | 8 | 0 | 5 |
For details and further investigation, click here
