| Full name: fatty acid binding protein 5 | Alias Symbol: E-FABP|PA-FABP|KFABP | ||
| Type: protein-coding gene | Cytoband: 8q21.13 | ||
| Entrez ID: 2171 | HGNC ID: HGNC:3560 | Ensembl Gene: ENSG00000164687 | OMIM ID: 605168 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FABP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FABP5 | 2171 | 202345_s_at | -0.5529 | 0.6257 | |
| GSE20347 | FABP5 | 2171 | 202345_s_at | -0.5411 | 0.1441 | |
| GSE23400 | FABP5 | 2171 | 202345_s_at | -0.1702 | 0.4088 | |
| GSE26886 | FABP5 | 2171 | 202345_s_at | -1.4799 | 0.0014 | |
| GSE29001 | FABP5 | 2171 | 202345_s_at | -0.4874 | 0.3087 | |
| GSE38129 | FABP5 | 2171 | 202345_s_at | -0.0273 | 0.9566 | |
| GSE45670 | FABP5 | 2171 | 202345_s_at | 0.2280 | 0.0328 | |
| GSE53622 | FABP5 | 2171 | 68260 | -0.1913 | 0.5256 | |
| GSE53624 | FABP5 | 2171 | 68260 | -0.3223 | 0.0187 | |
| GSE63941 | FABP5 | 2171 | 202345_s_at | 1.9030 | 0.3932 | |
| GSE77861 | FABP5 | 2171 | 202345_s_at | -0.0674 | 0.6868 | |
| GSE97050 | FABP5 | 2171 | A_32_P204676 | 1.4361 | 0.1678 | |
| SRP007169 | FABP5 | 2171 | RNAseq | -2.8370 | 0.0000 | |
| SRP008496 | FABP5 | 2171 | RNAseq | -1.6501 | 0.0031 | |
| SRP064894 | FABP5 | 2171 | RNAseq | -0.5663 | 0.1612 | |
| SRP133303 | FABP5 | 2171 | RNAseq | -0.0344 | 0.9438 | |
| SRP159526 | FABP5 | 2171 | RNAseq | -1.6047 | 0.0579 | |
| SRP193095 | FABP5 | 2171 | RNAseq | -0.8991 | 0.0210 | |
| SRP219564 | FABP5 | 2171 | RNAseq | -1.3027 | 0.1612 | |
| TCGA | FABP5 | 2171 | RNAseq | 0.8703 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by FABP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FABP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FABP5 | 2171 | 16 | 1 | 13 | |
| GSE20123 | FABP5 | 2171 | 18 | 1 | 11 | |
| GSE43470 | FABP5 | 2171 | 18 | 1 | 24 | |
| GSE46452 | FABP5 | 2171 | 21 | 0 | 38 | |
| GSE47630 | FABP5 | 2171 | 23 | 0 | 17 | |
| GSE54993 | FABP5 | 2171 | 0 | 19 | 51 | |
| GSE54994 | FABP5 | 2171 | 30 | 0 | 23 | |
| GSE60625 | FABP5 | 2171 | 0 | 4 | 7 | |
| GSE74703 | FABP5 | 2171 | 15 | 1 | 20 | |
| GSE74704 | FABP5 | 2171 | 12 | 0 | 8 | |
| TCGA | FABP5 | 2171 | 50 | 3 | 43 |
Total number of gains: 203; Total number of losses: 30; Total Number of normals: 255.
Somatic mutations of FABP5:
Generating mutation plots.
Highly correlated genes for FABP5:
Showing top 20/254 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FABP5 | KRT16 | 0.713279 | 11 | 0 | 11 |
| FABP5 | KRT6C | 0.710933 | 4 | 0 | 4 |
| FABP5 | S100A8 | 0.691867 | 11 | 0 | 9 |
| FABP5 | S100A9 | 0.674881 | 11 | 0 | 9 |
| FABP5 | SBSN | 0.673562 | 6 | 0 | 5 |
| FABP5 | CLCA2 | 0.670063 | 11 | 0 | 9 |
| FABP5 | S100A2 | 0.665987 | 11 | 0 | 10 |
| FABP5 | DSG3 | 0.66583 | 10 | 0 | 9 |
| FABP5 | KRT6A | 0.655814 | 13 | 0 | 11 |
| FABP5 | MAP4 | 0.654827 | 3 | 0 | 3 |
| FABP5 | KRT6B | 0.65422 | 12 | 0 | 9 |
| FABP5 | SFN | 0.652752 | 12 | 0 | 10 |
| FABP5 | SPRR1B | 0.649814 | 11 | 0 | 8 |
| FABP5 | DSP | 0.647464 | 10 | 0 | 9 |
| FABP5 | TUBA4A | 0.637744 | 12 | 0 | 10 |
| FABP5 | ETF1 | 0.637201 | 4 | 0 | 4 |
| FABP5 | RNF128 | 0.629945 | 4 | 0 | 3 |
| FABP5 | SLC27A4 | 0.62934 | 5 | 0 | 4 |
| FABP5 | BTBD11 | 0.625647 | 4 | 0 | 3 |
| FABP5 | SERPINB5 | 0.62298 | 11 | 0 | 7 |
For details and further investigation, click here
