| Full name: urocortin 2 | Alias Symbol: UCNI|SRP|URP|UCN-II | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 90226 | HGNC ID: HGNC:18414 | Ensembl Gene: ENSG00000145040 | OMIM ID: 605902 |
| Drug and gene relationship at DGIdb | |||
Expression of UCN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UCN2 | 90226 | 232674_at | 0.8272 | 0.1258 | |
| GSE26886 | UCN2 | 90226 | 232674_at | 0.8829 | 0.0001 | |
| GSE45670 | UCN2 | 90226 | 232674_at | 0.3479 | 0.0490 | |
| GSE53622 | UCN2 | 90226 | 155511 | 0.1499 | 0.4082 | |
| GSE53624 | UCN2 | 90226 | 155511 | 0.4353 | 0.0005 | |
| GSE63941 | UCN2 | 90226 | 232674_at | -0.1485 | 0.5423 | |
| GSE77861 | UCN2 | 90226 | 232674_at | -0.0118 | 0.9676 | |
| GSE97050 | UCN2 | 90226 | A_33_P3279629 | 0.4421 | 0.3168 | |
| SRP133303 | UCN2 | 90226 | RNAseq | 2.4606 | 0.0000 | |
| SRP159526 | UCN2 | 90226 | RNAseq | 2.9064 | 0.0001 | |
| SRP219564 | UCN2 | 90226 | RNAseq | 1.3599 | 0.0598 | |
| TCGA | UCN2 | 90226 | RNAseq | 2.3231 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by UCN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UCN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UCN2 | 90226 | 0 | 18 | 12 | |
| GSE20123 | UCN2 | 90226 | 0 | 19 | 11 | |
| GSE43470 | UCN2 | 90226 | 0 | 19 | 24 | |
| GSE46452 | UCN2 | 90226 | 3 | 16 | 40 | |
| GSE47630 | UCN2 | 90226 | 1 | 24 | 15 | |
| GSE54993 | UCN2 | 90226 | 6 | 2 | 62 | |
| GSE54994 | UCN2 | 90226 | 0 | 36 | 17 | |
| GSE60625 | UCN2 | 90226 | 5 | 0 | 6 | |
| GSE74703 | UCN2 | 90226 | 0 | 15 | 21 | |
| GSE74704 | UCN2 | 90226 | 0 | 12 | 8 | |
| TCGA | UCN2 | 90226 | 0 | 78 | 18 |
Total number of gains: 15; Total number of losses: 239; Total Number of normals: 234.
Somatic mutations of UCN2:
Generating mutation plots.
Highly correlated genes for UCN2:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UCN2 | RUNX1-IT1 | 0.759416 | 3 | 0 | 3 |
| UCN2 | GALNT6 | 0.729166 | 3 | 0 | 3 |
| UCN2 | TNFRSF12A | 0.716413 | 3 | 0 | 3 |
| UCN2 | CACTIN | 0.713475 | 3 | 0 | 3 |
| UCN2 | TOMM40 | 0.707334 | 4 | 0 | 3 |
| UCN2 | APCDD1L | 0.707205 | 3 | 0 | 3 |
| UCN2 | COL7A1 | 0.697622 | 8 | 0 | 8 |
| UCN2 | KPTN | 0.69228 | 3 | 0 | 3 |
| UCN2 | CHAF1A | 0.688929 | 3 | 0 | 3 |
| UCN2 | LIG1 | 0.688708 | 3 | 0 | 3 |
| UCN2 | ZNF593 | 0.680018 | 4 | 0 | 3 |
| UCN2 | GPR153 | 0.677603 | 4 | 0 | 3 |
| UCN2 | COL10A1 | 0.675803 | 3 | 0 | 3 |
| UCN2 | SPATS2 | 0.673317 | 4 | 0 | 3 |
| UCN2 | ATG2A | 0.672163 | 4 | 0 | 4 |
| UCN2 | TMEM132A | 0.671526 | 4 | 0 | 3 |
| UCN2 | ORC6 | 0.668575 | 4 | 0 | 3 |
| UCN2 | MCM4 | 0.668027 | 4 | 0 | 3 |
| UCN2 | APOC1 | 0.666153 | 3 | 0 | 3 |
| UCN2 | GTSE1 | 0.666039 | 4 | 0 | 3 |
For details and further investigation, click here
